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    CMK2 calmodulin-dependent protein kinase CMK2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 854144, updated on 17-May-2024

    Summary

    Gene symbol
    CMK2
    Gene description
    calmodulin-dependent protein kinase CMK2
    Primary source
    FungiDB:YOL016C
    Locus tag
    YOL016C
    See related
    SGD:S000005376; AllianceGenome:SGD:S000005376; VEuPathDB:YOL016C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables calmodulin-dependent protein kinase activity. Involved in protein phosphorylation. Located in cytoplasm. Orthologous to several human genes including CAMK1G (calcium/calmodulin dependent protein kinase IG) and PNCK (pregnancy up-regulated nonubiquitous CaM kinase). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See CMK2 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (294777..296120, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Tlg2p Neighboring gene Esc8p Neighboring gene Irc10p Neighboring gene uncharacterized protein

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    calmodulin-dependent protein kinase CMK2
    NP_014626.1
    • Calmodulin-dependent protein kinase; negative feedback controller of calcium/calcineurin signalling pathway, also has additional Crz1-independent role in promoting calcium tolerance; amino acid sequence similar to mammalian Cam Kinase II; CMK2 has a paralog, CMK1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      294777..296120 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183270.1NP_014626.1  TPA: calmodulin-dependent protein kinase CMK2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014626.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W250, P22517
      UniProtKB/TrEMBL
      A0A6A5Q3H7, A6ZNJ1, B3LJ41, B5VRN9, C7GQW6, C8ZHU8, N1NWD9
      Conserved Domains (2) summary
      smart00220
      Location:47309
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd05117
      Location:46308
      STKc_CAMK; The catalytic domain of CAMK family Serine/Threonine Kinases