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    YGK3 serine/threonine protein kinase YGK3 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853992, updated on 17-May-2024

    Summary

    Gene symbol
    YGK3
    Gene description
    serine/threonine protein kinase YGK3
    Primary source
    FungiDB:YOL128C
    Locus tag
    YOL128C
    See related
    SGD:S000005488; AllianceGenome:SGD:S000005488; VEuPathDB:YOL128C
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein serine/threonine kinase activity. Involved in several processes, including cellular response to heat; cellular response to salt stress; and protein phosphorylation. Predicted to be part of mediator complex. Predicted to be active in nucleus. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See YGK3 in Genome Data Viewer
    Location:
    chromosome: XV
    Exon count:
    1
    Sequence:
    Chromosome: XV; NC_001147.6 (78352..79479, complement)

    Chromosome XV - NC_001147.6Genomic Context describing neighboring genes Neighboring gene Mg(2+) transporter ALR1 Neighboring gene Vps68p Neighboring gene ribosomal 60S subunit protein L25 Neighboring gene malate dehydrogenase MDH2

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity HDA PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in proteolysis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in cellular_component ND
    No biological Data available
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    serine/threonine protein kinase YGK3
    NP_014513.1
    • Protein kinase related to mammalian GSK-3 glycogen synthase kinases; GSK-3 homologs (Mck1p, Rim11p, Mrk1p, Ygk3p) are involved in control of Msn2p-dependent transcription of stress responsive genes and in protein degradation; YGK3 has a paralog, MCK1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001147.6 Reference assembly

      Range
      78352..79479 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001183382.1NP_014513.1  TPA: serine/threonine protein kinase YGK3 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_014513.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6W1U0, Q12222
      UniProtKB/TrEMBL
      A0A8H4BVN6, A6ZN83, C7GV04, N1NVV3
      Conserved Domains (2) summary
      smart00220
      Location:44329
      S_TKc; Serine/Threonine protein kinases, catalytic domain
      cd14137
      Location:35332
      STKc_GSK3; The catalytic domain of the Serine/Threonine Kinase, Glycogen Synthase Kinase 3