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    NET1 Net1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853369, updated on 9-Jun-2024

    Summary

    Gene symbol
    NET1
    Gene description
    Net1p
    Primary source
    FungiDB:YJL076W
    Locus tag
    YJL076W
    See related
    SGD:S000003612; AllianceGenome:SGD:S000003612; VEuPathDB:YJL076W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CFI1; ESC5; SRM8
    Summary
    Enables protein phosphatase inhibitor activity and rDNA binding activity. Involved in negative regulation of exit from mitosis; positive regulation of protein localization to nucleolus; and rDNA heterochromatin assembly. Located in nucleolus. Part of RENT complex. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See NET1 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (295245..298814)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene Ics3p Neighboring gene Apq13p Neighboring gene cohesin subunit SMC3 Neighboring gene Jem1p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables phosphatase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein phosphatase inhibitor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables rDNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables rDNA binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of RENT complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleolus IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Net1p
    NP_012459.1
    • Core subunit of the RENT complex; involved in nucleolar silencing and telophase exit; stimulates transcription by RNA polymerase I and regulates nucleolar structure; NET1 has a paralog, TOF2, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      295245..298814
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181509.1NP_012459.1  TPA: Net1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012459.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VWA8, P47035
      UniProtKB/TrEMBL
      A0A8H4FAJ3, N1P8G4
      Conserved Domains (2) summary
      pfam09528
      Location:472963
      Ehrlichia_rpt; Ehrlichia tandem repeat (Ehrlichia_rpt)
      pfam10407
      Location:71142
      Cytokin_check_N; Cdc14 phosphatase binding protein N-terminus