U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    VHS1 putative serine/threonine protein kinase VHS1 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 851834, updated on 17-May-2024

    Summary

    Gene symbol
    VHS1
    Gene description
    putative serine/threonine protein kinase VHS1
    Primary source
    FungiDB:YDR247W
    Locus tag
    YDR247W
    See related
    SGD:S000002655; AllianceGenome:SGD:S000002655; VEuPathDB:YDR247W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Enables protein serine/threonine kinase activity. Involved in G1/S transition of mitotic cell cycle; peptidyl-serine phosphorylation; and regulation of protein localization. Located in cytoplasm. [provided by Alliance of Genome Resources, Apr 2022]
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See VHS1 in Genome Data Viewer
    Location:
    chromosome: IV
    Exon count:
    1
    Sequence:
    Chromosome: IV; NC_001136.10 (956013..957398)

    Chromosome IV - NC_001136.10Genomic Context describing neighboring genes Neighboring gene TRAPP subunit TRS23 Neighboring gene uncharacterized protein Neighboring gene gluconokinase Neighboring gene uncharacterized protein

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity HDA PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in G1/S transition of mitotic cell cycle IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in protein phosphorylation IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of protein localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
     

    General protein information

    Preferred Names
    putative serine/threonine protein kinase VHS1
    NP_010533.1
    • Cytoplasmic serine/threonine protein kinase; identified as a high-copy suppressor of the synthetic lethality of a sis2 sit4 double mutant, suggesting a role in G1/S phase progression; VHS1 has a paralog, SKS1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001136.10 Reference assembly

      Range
      956013..957398
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001180555.1NP_010533.1  TPA: putative serine/threonine protein kinase VHS1 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_010533.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q03785
      UniProtKB/TrEMBL
      A0A8H8UNF2, B3LG41, B5VGD3, C7GTI3, C8Z5F9, N1P6N9
      Conserved Domains (1) summary
      cd13993
      Location:11330
      STKc_Pat1_like; Catalytic domain of Fungal Pat1-like Serine/Threonine kinases