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    RCK2 serine/threonine protein kinase RCK2 [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850950, updated on 17-May-2024

    Summary

    Gene symbol
    RCK2
    Gene description
    serine/threonine protein kinase RCK2
    Primary source
    FungiDB:YLR248W
    Locus tag
    YLR248W
    See related
    SGD:S000004238; AllianceGenome:SGD:S000004238; VEuPathDB:YLR248W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    CLK1; CMK3
    Summary
    Enables protein serine/threonine kinase activity. Involved in several processes, including cellular response to oxidative stress; osmosensory signaling pathway; and regulation of meiotic nuclear division. Located in cytoplasm. Orthologous to human CAMKV (CaM kinase like vesicle associated); PSKH1 (protein serine kinase H1); and PSKH2 (protein serine kinase H2). [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See RCK2 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (634252..636084)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene tRNA-Leu Neighboring gene E3 ubiquitin-protein ligase IRC20 Neighboring gene translation elongation factor EF-3 Neighboring gene Ssp120p

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables calmodulin binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein kinase activity HDA PubMed 
    enables protein kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein serine/threonine kinase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein serine/threonine kinase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm HDA PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    serine/threonine protein kinase RCK2
    NP_013349.1
    • Protein kinase involved in response to oxidative and osmotic stress; identified as suppressor of S. pombe cell cycle checkpoint mutations; similar to CaM (calmodulin) kinases; RCK2 has a paralog, RCK1, that arose from the whole genome duplication

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      634252..636084
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001182135.1NP_013349.1  TPA: serine/threonine protein kinase RCK2 [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013349.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VYP6, P38623, Q02532, Q06557
      UniProtKB/TrEMBL
      A0A6A5PSW9, A7A1D1, C7GQY8, G2WJ74, N1NZG9
      Conserved Domains (1) summary
      cd14096
      Location:161478
      STKc_RCK1-like; Catalytic domain of RCK1-like Serine/Threonine Kinases