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    SFI1 Sfi1p [ Saccharomyces cerevisiae S288C ]

    Gene ID: 850657, updated on 17-May-2024

    Summary

    Gene symbol
    SFI1
    Gene description
    Sfi1p
    Primary source
    FungiDB:YLL003W
    Locus tag
    YLL003W
    See related
    SGD:S000003926; AllianceGenome:SGD:S000003926; VEuPathDB:YLL003W
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Summary
    Involved in G2/M transition of mitotic cell cycle; spindle assembly; and spindle pole body duplication. Located in half bridge of spindle pole body. [provided by Alliance of Genome Resources, Apr 2022]
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    Genomic context

    See SFI1 in Genome Data Viewer
    Location:
    chromosome: XII
    Exon count:
    1
    Sequence:
    Chromosome: XII; NC_001144.5 (143201..146041)

    Chromosome XII - NC_001144.5Genomic Context describing neighboring genes Neighboring gene Spo75p Neighboring gene origin recognition complex subunit 3 Neighboring gene H3 histone acetyltransferase RTT109 Neighboring gene dynamin-related GTPase DNM1

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Gene Ontology Provided by SGD

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in G2/M transition of mitotic cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in cell division IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spindle pole body duplication IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in half bridge of spindle pole body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in spindle pole IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    Sfi1p
    NP_013098.1
    • Centrin (Cdc31p)-binding protein required for SPB duplication; localizes to the half-bridge of the spindle pole body (SPB); required for progression through G(2)-M transition; phosphorylated by Cdc28p-Clb2p and by Cdc5p; dephosphorylated by Cdc14p; has similarity to Xenopus laevis XCAP-C

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001144.5 Reference assembly

      Range
      143201..146041
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181823.1NP_013098.1  TPA: Sfi1p [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_013098.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      D6VY00, Q12369
      UniProtKB/TrEMBL
      A0A8H4BZ45, B3LTG3, C7GPG0
      Conserved Domains (2) summary
      pfam08457
      Location:259794
      Sfi1; Sfi1 spindle body protein
      pfam10638
      Location:812913
      Sfi1_C; Spindle body associated protein C-terminus