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    PIP5K1B phosphatidylinositol-4-phosphate 5-kinase type 1 beta [ Homo sapiens (human) ]

    Gene ID: 8395, updated on 9-Dec-2018

    Summary

    Official Symbol
    PIP5K1Bprovided by HGNC
    Official Full Name
    phosphatidylinositol-4-phosphate 5-kinase type 1 betaprovided by HGNC
    Primary source
    HGNC:HGNC:8995
    See related
    Ensembl:ENSG00000107242 MIM:602745
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MSS4; STM7
    Expression
    Broad expression in colon (RPKM 8.2), duodenum (RPKM 7.6) and 20 other tissues See more
    Orthologs

    Genomic context

    See PIP5K1B in Genome Data Viewer
    Location:
    9q21.11
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 9 NC_000009.12 (68705217..69009176)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (71320188..71624092)

    Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105376072 Neighboring gene uncharacterized LOC105376071 Neighboring gene dermatan sulfate epimerase pseudogene Neighboring gene adaptor related protein complex 3 mu 2 subunit pseudogene Neighboring gene family with sequence similarity 122A Neighboring gene uncharacterized LOC101927069 Neighboring gene RNA, U6 small nuclear 820, pseudogene Neighboring gene Friedreich ataxia repeat instability region Neighboring gene protein kinase cAMP-activated catalytic subunit gamma Neighboring gene frataxin

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Jun 15 11:32:44 2016

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Phenotypes

    NHGRI GWAS Catalog

    Description
    Gene-environment interactions and obesity traits among postmenopausal African-American and Hispanic women in the Women's Health Initiative SHARe Study.
    NHGRI GWA Catalog
    Genome-wide association studies of pit-and-fissure- and smooth-surface caries in permanent dentition.
    NHGRI GWA Catalog
    New loci associated with kidney function and chronic kidney disease.
    NHGRI GWA Catalog

    Pathways from BioSystems

    • 3-phosphoinositide biosynthesis, organism-specific biosystem (from BIOCYC)
      3-phosphoinositide biosynthesis, organism-specific biosystem: Phosphoinositides "Phosphoinositides" play a key role in signal transduction, transmitting signals from the cell surface to modulate intracellular processes. One well known phosphoinositide pathway...
    • 3-phosphoinositide biosynthesis, conserved biosystem (from BIOCYC)
      3-phosphoinositide biosynthesis, conserved biosystem|FRAME: Phosphoinositides "Phosphoinositides"| play a key role in signal transduction in the eukaryotic cell, transmitting signals from the cell surface to modulate intracellular processes. One well ...
    • Adaptive Immune System, organism-specific biosystem (from REACTOME)
      Adaptive Immune System, organism-specific biosystemAdaptive immunity refers to antigen-specific immune response efficiently involved in clearing the pathogens. The adaptive immune system is comprised of B and T lymphocytes that express receptors with...
    • B Cell Receptor Signaling Pathway, organism-specific biosystem (from WikiPathways)
      B Cell Receptor Signaling Pathway, organism-specific biosystemThe functional B-cell receptor is a multi-protein complex consisting of an antigen binding subunit and a signaling subunit. The antigen binding subunit is the membrane bound immunoglobulin and the si...
    • Canonical Wnt signaling pathway, organism-specific biosystem (from Pathway Interaction Database)
      Canonical Wnt signaling pathway, organism-specific biosystem
      Canonical Wnt signaling pathway
    • Choline metabolism in cancer, organism-specific biosystem (from KEGG)
      Choline metabolism in cancer, organism-specific biosystemAbnormal choline metabolism is emerging as a metabolic hallmark that is associated with oncogenesis and tumour progression. Following transformation, oncogenic signalling via pathways such as the RAS...
    • Choline metabolism in cancer, conserved biosystem (from KEGG)
      Choline metabolism in cancer, conserved biosystemAbnormal choline metabolism is emerging as a metabolic hallmark that is associated with oncogenesis and tumour progression. Following transformation, oncogenic signalling via pathways such as the RAS...
    • D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystem (from BIOCYC)
      D-myo-inositol (1,4,5)-trisphosphate biosynthesis, organism-specific biosystemGeneral Background : MYO-INOSITOL "myo-Inositol"-containing phospholipids play an important role in the control of cellular functions within eukaryotic cells, being part of the intracellular signal ...
    • D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystem (from BIOCYC)
      D-myo-inositol (1,4,5)-trisphosphate biosynthesis, conserved biosystemGeneral Background |FRAME: MYO-INOSITOL "myo-Inositol"|-containing phospholipids play an important role in the control of cellular functions within eukaryotic cells, being part of the intracellular ...
    • DAP12 interactions, organism-specific biosystem (from REACTOME)
      DAP12 interactions, organism-specific biosystemDNAX activation protein of 12kDa (DAP12) is an immunoreceptor tyrosine-based activation motif (ITAM)-bearing adapter molecule that transduces activating signals in natural killer (NK) and myeloid cel...
    • DAP12 signaling, organism-specific biosystem (from REACTOME)
      DAP12 signaling, organism-specific biosystemIn response to receptor ligation, the tyrosine residues in DAP12's immunoreceptor tyrosine-based activation motif (ITAM) are phosphorylated by Src family kinases. These phosphotyrosines form the dock...
    • Downstream signal transduction, organism-specific biosystem (from REACTOME)
      Downstream signal transduction, organism-specific biosystemThe role of autophosphorylation sites on PDGF receptors are to provide docking sites for downstream signal transduction molecules which contain SH2 domains. The SH2 domain is a conserved motif of aro...
    • Downstream signaling events of B Cell Receptor (BCR), organism-specific biosystem (from REACTOME)
      Downstream signaling events of B Cell Receptor (BCR), organism-specific biosystemSecond messengers (calcium, diacylglycerol, inositol 1,4,5-trisphosphate, and phosphatidyinositol 3,4,5-trisphosphate) trigger signaling pathways: NF-kappaB is activated via protein kinase C beta, RA...
    • Endocytosis, organism-specific biosystem (from KEGG)
      Endocytosis, organism-specific biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Endocytosis, conserved biosystem (from KEGG)
      Endocytosis, conserved biosystemEndocytosis is a mechanism for cells to remove ligands, nutrients, and plasma membrane (PM) proteins, and lipids from the cell surface, bringing them into the cell interior. Transmembrane proteins en...
    • Fc epsilon receptor (FCERI) signaling, organism-specific biosystem (from REACTOME)
      Fc epsilon receptor (FCERI) signaling, organism-specific biosystemMast cells (MC) are distributed in tissues throughout the human body and have long been recognized as key cells of type I hypersensitivity reactions. They also play important roles in inflammatory an...
    • Fc gamma R-mediated phagocytosis, organism-specific biosystem (from KEGG)
      Fc gamma R-mediated phagocytosis, organism-specific biosystemPhagocytosis plays an essential role in host-defense mechanisms through the uptake and destruction of infectious pathogens. Specialized cell types including macrophages, neutrophils, and monocytes ta...
    • Fc gamma R-mediated phagocytosis, conserved biosystem (from KEGG)
      Fc gamma R-mediated phagocytosis, conserved biosystemPhagocytosis plays an essential role in host-defense mechanisms through the uptake and destruction of infectious pathogens. Specialized cell types including macrophages, neutrophils, and monocytes ta...
    • GAB1 signalosome, organism-specific biosystem (from REACTOME)
      GAB1 signalosome, organism-specific biosystemGAB1 is recruited to the activated EGFR indirectly, through GRB2. GAB1 acts as an adaptor protein that enables formation of an active PIK3, through recruitment of PIK3 regulatory subunit PIK3R1 (also...
    • Immune System, organism-specific biosystem (from REACTOME)
      Immune System, organism-specific biosystemHumans are exposed to millions of potential pathogens daily, through contact, ingestion, and inhalation. Our ability to avoid infection depends on the adaptive immune system and during the first crit...
    • Innate Immune System, organism-specific biosystem (from REACTOME)
      Innate Immune System, organism-specific biosystemInnate immunity encompases the nonspecific part of immunity tha are part of an individual's natural biologic makeup
    • Inositol phosphate metabolism, organism-specific biosystem (from KEGG)
      Inositol phosphate metabolism, organism-specific biosystem
      Inositol phosphate metabolism
    • Inositol phosphate metabolism, conserved biosystem (from KEGG)
      Inositol phosphate metabolism, conserved biosystem
      Inositol phosphate metabolism
    • Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4, organism-specific biosystem (from KEGG)
      Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4, organism-specific biosystemPathway module; Carbohydrate and lipid metabolism; Lipid metabolism
    • Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4, conserved biosystem (from KEGG)
      Inositol phosphate metabolism, PI=> PIP2 => Ins(1,4,5)P3 => Ins(1,3,4,5)P4, conserved biosystemPathway module; Carbohydrate and lipid metabolism; Lipid metabolism
    • Metabolic pathways, organism-specific biosystem (from KEGG)
      Metabolic pathways, organism-specific biosystem
      Metabolic pathways
    • Metabolism, organism-specific biosystem (from REACTOME)
      Metabolism, organism-specific biosystemMetabolic processes in human cells generate energy through the oxidation of molecules consumed in the diet and mediate the synthesis of diverse essential molecules not taken in the diet as well as th...
    • Metabolism of lipids and lipoproteins, organism-specific biosystem (from REACTOME)
      Metabolism of lipids and lipoproteins, organism-specific biosystemLipids are hydrophobic but otherwise chemically diverse molecules that play a wide variety of roles in human biology. They include ketone bodies, fatty acids, triacylglycerols, phospholipids and sphi...
    • NGF signalling via TRKA from the plasma membrane, organism-specific biosystem (from REACTOME)
      NGF signalling via TRKA from the plasma membrane, organism-specific biosystemTrk receptors signal from the plasma membrane and from intracellular membranes, particularly from early endosomes. Signalling from the plasma membrane is fast but transient; signalling from endosomes...
    • Negative regulation of the PI3K/AKT network, organism-specific biosystem (from REACTOME)
      Negative regulation of the PI3K/AKT network, organism-specific biosystemThe PI3K/AKT network is negatively regulated by phosphatases that dephosphorylate PIP3, thus hampering AKT activation.
    • PI Metabolism, organism-specific biosystem (from REACTOME)
      PI Metabolism, organism-specific biosystemPhosphatidylinositol (PI), a membrane phospholipid, can be reversibly phosphorylated at the 3, 4, and 5 positions of the inositol ring to generate seven phosphoinositides: phosphatidylinositol 3-phos...
    • PI3K/AKT activation, organism-specific biosystem (from REACTOME)
      PI3K/AKT activation, organism-specific biosystemPI3K/AKT signalling is a major regulator of neuron survival. It blocks cell death by both impinging on the cytoplasmic cell death machinery and by regulating the expression of genes involved in cell...
    • PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, organism-specific biosystem (from REACTOME)
      PI5P, PP2A and IER3 Regulate PI3K/AKT Signaling, organism-specific biosystemPhosphatidylinositol-5-phosphate (PI5P) may modulate PI3K/AKT signaling in several ways. PI5P is used as a substrate for production of phosphatidylinositol-4,5-bisphosphate, PI(4,5)P2 (Rameh et al. 1...
    • PIP3 activates AKT signaling, organism-specific biosystem (from REACTOME)
      PIP3 activates AKT signaling, organism-specific biosystemSignaling by AKT is one of the key outcomes of receptor tyrosine kinase (RTK) activation. AKT is activated by the cellular second messenger PIP3, a phospholipid that is generated by PI3K. In ustimula...
    • Phosphatidylinositol signaling system, organism-specific biosystem (from KEGG)
      Phosphatidylinositol signaling system, organism-specific biosystem
      Phosphatidylinositol signaling system
    • Phosphatidylinositol signaling system, conserved biosystem (from KEGG)
      Phosphatidylinositol signaling system, conserved biosystem
      Phosphatidylinositol signaling system
    • Phospholipase D signaling pathway, organism-specific biosystem (from KEGG)
      Phospholipase D signaling pathway, organism-specific biosystemPhospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second messenger phosphatidic acid (PA), which is involved in fundamental cellular processes, including membra...
    • Phospholipase D signaling pathway, conserved biosystem (from KEGG)
      Phospholipase D signaling pathway, conserved biosystemPhospholipase D (PLD) is an essential enzyme responsible for the production of the lipid second messenger phosphatidic acid (PA), which is involved in fundamental cellular processes, including membra...
    • Phospholipid metabolism, organism-specific biosystem (from REACTOME)
      Phospholipid metabolism, organism-specific biosystemPhospholipids contain a polar head group and two long-chain fatty acyl moieties, one of which is generally unsaturated. The head group is a glycerol or serine phosphate attached to a polar group such...
    • RAC1 signaling pathway, organism-specific biosystem (from Pathway Interaction Database)
      RAC1 signaling pathway, organism-specific biosystem
      RAC1 signaling pathway
    • Regulation of Actin Cytoskeleton, organism-specific biosystem (from WikiPathways)
      Regulation of Actin Cytoskeleton, organism-specific biosystemhttp://www.genome.jp/kegg/pathway/hsa/hsa04810.html
    • Regulation of actin cytoskeleton, organism-specific biosystem (from KEGG)
      Regulation of actin cytoskeleton, organism-specific biosystem
      Regulation of actin cytoskeleton
    • Regulation of actin cytoskeleton, conserved biosystem (from KEGG)
      Regulation of actin cytoskeleton, conserved biosystem
      Regulation of actin cytoskeleton
    • RhoA signaling pathway, organism-specific biosystem (from Pathway Interaction Database)
      RhoA signaling pathway, organism-specific biosystem
      RhoA signaling pathway
    • Role of LAT2/NTAL/LAB on calcium mobilization, organism-specific biosystem (from REACTOME)
      Role of LAT2/NTAL/LAB on calcium mobilization, organism-specific biosystemThe lipid raft resident adaptor molecules LAT1 and Non-T cell activation linker (NTAL), also known as linker for activation of B cells (LAB)/LAT2 are known participants in the regulation of mast cell...
    • Signal Transduction, organism-specific biosystem (from REACTOME)
      Signal Transduction, organism-specific biosystemSignal transduction is a process in which extracellular signals elicit changes in cell state and activity. Transmembrane receptors sense changes in the cellular environment by binding ligands, such a...
    • Signaling by EGFR, organism-specific biosystem (from REACTOME)
      Signaling by EGFR, organism-specific biosystemThe epidermal growth factor receptor (EGFR) is one member of the ERBB family of transmembrane glycoprotein tyrosine receptor kinases (RTK). Binding of EGFR to its ligands induces conformational chang...
    • Signaling by PDGF, organism-specific biosystem (from REACTOME)
      Signaling by PDGF, organism-specific biosystemPlatelet-derived Growth Factor (PDGF) is a potent stimulator of growth and motility of connective tissue cells such as fibroblasts and smooth muscle cells as well as other cells such as capillary end...
    • Signaling by SCF-KIT, organism-specific biosystem (from REACTOME)
      Signaling by SCF-KIT, organism-specific biosystemStem cell factor (SCF) is a growth factor with membrane bound and soluble forms. It is expressed by fibroblasts and endothelial cells throughout the body, promoting proliferation, migration, survival...
    • Signaling by Wnt, organism-specific biosystem (from REACTOME)
      Signaling by Wnt, organism-specific biosystemWNT signaling pathways control a wide range of developmental and adult process in metozoans including cell proliferation, cell fate decisions, cell polarity and stem cell maintenance (reviewed in Sai...
    • Signaling by the B Cell Receptor (BCR), organism-specific biosystem (from REACTOME)
      Signaling by the B Cell Receptor (BCR), organism-specific biosystemMature B cells express IgM and IgD immunoglobulins which are complexed at the plasma membrane with Ig-alpha (CD79A, MB-1) and Ig-beta (CD79B, B29) to form the B cell receptor (BCR) (Fu et al. 1974, F...
    • Signalling by NGF, organism-specific biosystem (from REACTOME)
      Signalling by NGF, organism-specific biosystemNeurotrophins (NGF, BDNF, NT-3, NT-4/5) play pivotal roles in survival, differentiation, and plasticity of neurons in the peripheral and central nervous system. They are produced, and secreted in mi...
    • Synthesis of PIPs at the plasma membrane, organism-specific biosystem (from REACTOME)
      Synthesis of PIPs at the plasma membrane, organism-specific biosystemAt the plasma membrane, subsequent phosphorylation of phosphatidylinositol 4-phosphate (PI4P) produces phosphatidylinositol 4,5-bisphosphate (PI(4,5)P2) and phosphatidylinositol 3,4,5-trisphosphate (...
    • TCF dependent signaling in response to WNT, organism-specific biosystem (from REACTOME)
      TCF dependent signaling in response to WNT, organism-specific biosystem19 WNT ligands and 10 FZD receptors have been identified in human cells; interactions amongst these ligands and receptors vary in a developmental and tissue-specific manner and lead to activation of ...
    • WNT mediated activation of DVL, organism-specific biosystem (from REACTOME)
      WNT mediated activation of DVL, organism-specific biosystemThe three human Dishevelled (DVL) proteins play a central and overlapping role in the transduction of the WNT signaling cascade (Lee et al, 2008; reviewed in Gao and Chen 2010). DVL activity is regu...
    • Wnt Signaling Pathway Netpath, organism-specific biosystem (from WikiPathways)
      Wnt Signaling Pathway Netpath, organism-specific biosystemWNT signal, through the canonical pathway, controls cell fate determination and through the non-canonical pathway controls cell movement and tissue polarity. The name "wnt" is a fusion of two terms, ...
    • superpathway of inositol phosphate compounds, organism-specific biosystem (from BIOCYC)
      superpathway of inositol phosphate compounds, organism-specific biosystem
      superpathway of inositol phosphate compounds

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    1-phosphatidylinositol-3-phosphate 4-kinase activity TAS
    Traceable Author Statement
    more info
     
    1-phosphatidylinositol-3-phosphate 5-kinase activity TAS
    Traceable Author Statement
    more info
     
    1-phosphatidylinositol-4-phosphate 5-kinase activity NAS
    Non-traceable Author Statement
    more info
    PubMed 
    1-phosphatidylinositol-4-phosphate 5-kinase activity TAS
    Traceable Author Statement
    more info
     
    1-phosphatidylinositol-5-kinase activity TAS
    Traceable Author Statement
    more info
     
    ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylinositol-3,4-bisphosphate 5-kinase activity TAS
    Traceable Author Statement
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    phosphatidylinositol biosynthetic process TAS
    Traceable Author Statement
    more info
     
    phosphatidylinositol phosphorylation IEA
    Inferred from Electronic Annotation
    more info
     
    regulation of phosphatidylinositol 3-kinase signaling TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    cytosol TAS
    Traceable Author Statement
    more info
     
    endomembrane system IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    uropod IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    phosphatidylinositol 4-phosphate 5-kinase type-1 beta
    Names
    PIP5K1-beta
    PIP5KIbeta
    phosphatidylinositol 4-phosphate 5-kinase type I beta
    protein STM-7
    ptdIns(4)P-5-kinase 1 beta
    type I phosphatidylinositol 4-phosphate 5-kinase beta
    NP_001265182.1
    NP_003549.1
    XP_005252318.1
    XP_005252319.1
    XP_006717363.1
    XP_006717364.1
    XP_011517384.1
    XP_011517385.1
    XP_011517386.1
    XP_016870677.1
    XP_016870678.1
    XP_016870679.1
    XP_016870680.1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001278253.1NP_001265182.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 3

      See identical proteins and their annotated locations for NP_001265182.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and lacks an alternate exon in the 3' end, that causes a frameshift. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 2.
      Source sequence(s)
      AK295587, CB988216, CK299479
      Consensus CDS
      CCDS65063.1
      UniProtKB/Swiss-Prot
      O14986
      Related
      ENSP00000438082.1, ENST00000541509.5
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    2. NM_003558.4NP_003549.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform 2

      See identical proteins and their annotated locations for NP_003549.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) represents the longer transcript and encodes the longer isoform (2).
      Source sequence(s)
      AK292734, AL354794, CB988216, CK299479, U78579
      Consensus CDS
      CCDS6624.1
      UniProtKB/Swiss-Prot
      O14986
      UniProtKB/TrEMBL
      Q7KYT6
      Related
      ENSP00000265382.2, ENST00000265382.7
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000009.12 Reference GRCh38.p12 Primary Assembly

      Range
      68705217..69009176
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_005252261.3XP_005252318.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_005252318.1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    2. XM_006717301.1XP_006717364.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X2

      See identical proteins and their annotated locations for XP_006717364.1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    3. XM_017015188.1XP_016870677.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    4. XM_017015190.1XP_016870679.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    5. XM_006717300.2XP_006717363.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_006717363.1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    6. XM_017015191.1XP_016870680.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X2

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    7. XM_017015189.1XP_016870678.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    8. XM_011519083.2XP_011517385.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_011517385.1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    9. XM_011519082.2XP_011517384.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_011517384.1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    10. XM_011519084.3XP_011517386.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_011517386.1

      UniProtKB/Swiss-Prot
      O14986
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases
    11. XM_005252262.5XP_005252319.1  phosphatidylinositol 4-phosphate 5-kinase type-1 beta isoform X1

      See identical proteins and their annotated locations for XP_005252319.1

      UniProtKB/Swiss-Prot
      O14986
      Related
      ENSP00000435778.1, ENST00000478500.3
      Conserved Domains (1) summary
      smart00330
      Location:53393
      PIPKc; Phosphatidylinositol phosphate kinases

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_001031687.1: Suppressed sequence

      Description
      NM_001031687.1: This RefSeq was permanently suppressed because there is insufficient support for the transcript and the protein and because the transcript is a nonsense-mediated mRNA decay (NMD) candidate.
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