U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination
    • Showing Current items.

    CAB39L calcium binding protein 39 like [ Homo sapiens (human) ]

    Gene ID: 81617, updated on 10-Oct-2024

    Summary

    Official Symbol
    CAB39Lprovided by HGNC
    Official Full Name
    calcium binding protein 39 likeprovided by HGNC
    Primary source
    HGNC:HGNC:20290
    See related
    Ensembl:ENSG00000102547 MIM:612175; AllianceGenome:HGNC:20290
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    MO2L; MLAA-34; MO25-BETA; bA103J18.3
    Summary
    Predicted to enable protein serine/threonine kinase activator activity. Predicted to be involved in intracellular signal transduction. Predicted to be located in cytosol. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in prostate (RPKM 17.8), adrenal (RPKM 15.4) and 23 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See CAB39L in Genome Data Viewer
    Location:
    13q14.2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    RS_2024_08 current GRCh38.p14 (GCF_000001405.40) 13 NC_000013.11 (49308650..49444064, complement)
    RS_2024_08 current T2T-CHM13v2.0 (GCF_009914755.1) 13 NC_060937.1 (48529853..48662696, complement)
    RS_2024_09 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (49882786..50018200, complement)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105370203 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:49821922-49822484 Neighboring gene cytidine and dCMP deaminase domain containing 1 Neighboring gene Sharpr-MPRA regulatory region 13963 Neighboring gene Sharpr-MPRA regulatory region 6847 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr13:49880333-49880832 Neighboring gene P300/CBP strongly-dependent group 1 enhancer GRCh37_chr13:49888093-49889292 Neighboring gene NANOG hESC enhancer GRCh37_chr13:49961302-49961803 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7746 Neighboring gene H3K27ac hESC enhancer GRCh37_chr13:50018017-50018789 Neighboring gene SETDB2-PHF11 readthrough Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:50018790-50019563 Neighboring gene SET domain bifurcated histone lysine methyltransferase 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr13:50068895-50069580 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7748 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5342 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 7749 Neighboring gene small nuclear ribonucleoprotein polypeptide G pseudogene 14 Neighboring gene PHD finger protein 11

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ12577

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein serine/threonine kinase activator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Process Evidence Code Pubs
    involved_in intracellular signal transduction IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    Component Evidence Code Pubs
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol TAS
    Traceable Author Statement
    more info
     
    part_of serine/threonine protein kinase complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    calcium-binding protein 39-like
    Names
    MO25beta
    U937-associated antigen
    antigen MLAA-34
    mo25-like protein
    sarcoma antigen NY-SAR-79

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001079670.3NP_001073138.1  calcium-binding protein 39-like

      See identical proteins and their annotated locations for NP_001073138.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks a 5' non-coding exon compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AL138875, AW134845, BC010993, BX647518, DB051338
      Consensus CDS
      CCDS9416.2
      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
      UniProtKB/TrEMBL
      Q5TAW7
      Related
      ENSP00000386375.1, ENST00000409308.6
      Conserved Domains (1) summary
      pfam08569
      Location:6333
      Mo25; Mo25-like
    2. NM_001287337.2NP_001274266.1  calcium-binding protein 39-like

      See identical proteins and their annotated locations for NP_001274266.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript. Variants 1-5 encode the same protein.
      Source sequence(s)
      AL138875, AW134845, AY211923, AY288977, BX647518, DB051338
      Consensus CDS
      CCDS9416.2
      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
      UniProtKB/TrEMBL
      Q5TAW7
      Related
      ENSP00000386328.1, ENST00000410043.5
      Conserved Domains (1) summary
      pfam08569
      Location:6333
      Mo25; Mo25-like
    3. NM_001287338.2NP_001274267.1  calcium-binding protein 39-like

      See identical proteins and their annotated locations for NP_001274267.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) contains 3 alternate 5' non-coding exons compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AL138875, AW134845, AY211923, BX647518, DB033467, DB457246, HY043965
      Consensus CDS
      CCDS9416.2
      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
      UniProtKB/TrEMBL
      Q5TAW7
      Related
      ENSP00000479669.1, ENST00000610540.4
      Conserved Domains (1) summary
      pfam08569
      Location:6333
      Mo25; Mo25-like
    4. NM_001287339.2NP_001274268.1  calcium-binding protein 39-like

      See identical proteins and their annotated locations for NP_001274268.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks couple of exons, and contains two alternate exons in the 5' non-coding region compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AL138875, AW134845, AY211923, BX647518, DB457246
      Consensus CDS
      CCDS9416.2
      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
      UniProtKB/TrEMBL
      Q5TAW7
      Related
      ENSP00000261669.7, ENST00000347776.9
      Conserved Domains (1) summary
      pfam08569
      Location:6333
      Mo25; Mo25-like
    5. NM_030925.4NP_112187.2  calcium-binding protein 39-like

      See identical proteins and their annotated locations for NP_112187.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) lacks several exons, and contains an alternate exon in the 5' non-coding region compared to variant 1. Variants 1-5 encode the same protein.
      Source sequence(s)
      AL136218, AL138875, AW134845, AY211923, BC010993, BX647518, DB279812
      Consensus CDS
      CCDS9416.2
      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
      UniProtKB/TrEMBL
      Q5TAW7
      Related
      ENSP00000348113.4, ENST00000355854.8
      Conserved Domains (1) summary
      pfam08569
      Location:6333
      Mo25; Mo25-like

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2024_08

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p14 Primary Assembly

      Range
      49308650..49444064 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047430698.1XP_047286654.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    2. XM_047430696.1XP_047286652.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    3. XM_047430697.1XP_047286653.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    4. XM_047430695.1XP_047286651.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    5. XM_047430694.1XP_047286650.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    6. XM_047430699.1XP_047286655.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    7. XM_047430693.1XP_047286649.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060937.1 Alternate T2T-CHM13v2.0

      Range
      48529853..48662696 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054375061.1XP_054231036.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    2. XM_054375059.1XP_054231034.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    3. XM_054375058.1XP_054231033.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4
    4. XM_054375060.1XP_054231035.1  calcium-binding protein 39-like isoform X1

      UniProtKB/Swiss-Prot
      Q5TAW6, Q6WG71, Q96FG1, Q9BZ33, Q9H9S4