Format

Send to:

Choose Destination
    • Showing Current items.

    NAA16 N-alpha-acetyltransferase 16, NatA auxiliary subunit [ Homo sapiens (human) ]

    Gene ID: 79612, updated on 5-Sep-2021

    Summary

    Official Symbol
    NAA16provided by HGNC
    Official Full Name
    N-alpha-acetyltransferase 16, NatA auxiliary subunitprovided by HGNC
    Primary source
    HGNC:HGNC:26164
    See related
    Ensembl:ENSG00000172766 MIM:619497
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    NARG1L
    Expression
    Ubiquitous expression in bone marrow (RPKM 4.0), testis (RPKM 2.5) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See NAA16 in Genome Data Viewer
    Location:
    13q14.11
    Exon count:
    23
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 13 NC_000013.11 (41311239..41377031)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (41885403..41951166)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene mitochondrial translation release factor 1 Neighboring gene uncharacterized LOC105370173 Neighboring gene Rac family small GTPase 1 pseudogene 3 Neighboring gene RNA, U6 small nuclear 57, pseudogene Neighboring gene Sharpr-MPRA regulatory region 5068 Neighboring gene tubulin beta pseudogene 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC40612, DKFZp686O08147

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    contributes_to acetyltransferase activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    contributes_to peptide alpha-N-acetyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ribosome binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    contributes_to ribosome binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in N-terminal peptidyl-methionine acetylation IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in N-terminal protein amino acid acetylation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in N-terminal protein amino acid acetylation ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in protein stabilization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of NatA complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of NatA complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    located_in extracellular exosome HDA PubMed 
    located_in nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    part_of transcription regulator complex ISS
    Inferred from Sequence or Structural Similarity
    more info
     

    General protein information

    Preferred Names
    N-alpha-acetyltransferase 16, NatA auxiliary subunit
    Names
    NARG1-like protein
    NMDA receptor-regulated 1-like protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001110798.2NP_001104268.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 3

      See identical proteins and their annotated locations for NP_001104268.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks several coding exons and differs in the 3' UTR, compared to variant 1, resulting in a shorter protein (isoform 3) with a unique C-terminus, compared to isoform 1.
      Source sequence(s)
      AL590665, BC064592, BE501152, DB078940
      Consensus CDS
      CCDS45044.1
      UniProtKB/Swiss-Prot
      Q6N069
      Related
      ENSP00000386103.3, ENST00000403412.7
      Conserved Domains (3) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:82145
      TPR_11; TPR repeat
    2. NM_018527.4NP_060997.2  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 2

      See identical proteins and their annotated locations for NP_060997.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an internal coding exon and several 3' exons but has an alternate 3' segment, compared to variant 1. The resulting isoform (2) lacks an internal segment and has a shorter and distinct C-terminus, compared to isoform 1.
      Source sequence(s)
      AL590665, BC032318, DB078940
      UniProtKB/Swiss-Prot
      Q6N069
      Related
      ENST00000476980.5
      Conserved Domains (3) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:82145
      TPR_11; TPR repeat
    3. NM_024561.5NP_078837.3  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform 1

      See identical proteins and their annotated locations for NP_078837.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AK097224, AL590665, AL731858, AL833341, DB078940
      Consensus CDS
      CCDS9379.1
      UniProtKB/Swiss-Prot
      Q6N069
      UniProtKB/TrEMBL
      A4FU51
      Related
      ENSP00000368716.3, ENST00000379406.8
      Conserved Domains (4) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam12569
      Location:187698
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82145
      TPR_11; TPR repeat

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p13 Primary Assembly

      Range
      41311239..41377031
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006719866.3XP_006719929.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X1

      Conserved Domains (4) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam12569
      Location:187638
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82145
      TPR_11; TPR repeat
    2. XM_011535227.3XP_011533529.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X2

      Conserved Domains (4) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam12569
      Location:187698
      NARP1; NMDA receptor-regulated protein 1
      pfam13414
      Location:82145
      TPR_11; TPR repeat
    3. XM_011535228.2XP_011533530.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X3

      See identical proteins and their annotated locations for XP_011533530.1

      UniProtKB/Swiss-Prot
      Q6N069
      Related
      ENSP00000432364.1, ENST00000464857.5
      Conserved Domains (3) summary
      sd00006
      Location:82108
      TPR; TPR repeat [structural motif]
      pfam00515
      Location:87113
      TPR_1; Tetratricopeptide repeat
      pfam13414
      Location:82145
      TPR_11; TPR repeat
    4. XM_017020746.2XP_016876235.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X6

    5. XM_017020745.2XP_016876234.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X5

    6. XM_017020744.1XP_016876233.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X4

      Conserved Domains (1) summary
      pfam12569
      Location:1286
      NARP1; NMDA receptor-regulated protein 1
    7. XM_005266523.2XP_005266580.1  N-alpha-acetyltransferase 16, NatA auxiliary subunit isoform X4

      Conserved Domains (1) summary
      pfam12569
      Location:1286
      NARP1; NMDA receptor-regulated protein 1

    RNA

    1. XR_001749669.2 RNA Sequence

    2. XR_001749671.2 RNA Sequence

    3. XR_002957473.1 RNA Sequence

    4. XR_001749675.2 RNA Sequence

    5. XR_001749673.2 RNA Sequence

    6. XR_001749670.2 RNA Sequence

    Support Center