Format

Send to:

Choose Destination
    • Showing Current items.

    RGS7 regulator of G protein signaling 7 [ Homo sapiens (human) ]

    Gene ID: 6000, updated on 8-Jul-2021

    Summary

    Official Symbol
    RGS7provided by HGNC
    Official Full Name
    regulator of G protein signaling 7provided by HGNC
    Primary source
    HGNC:HGNC:10003
    See related
    Ensembl:ENSG00000182901 MIM:602517
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Expression
    Biased expression in brain (RPKM 5.9), adrenal (RPKM 1.5) and 2 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See RGS7 in Genome Data Viewer
    Location:
    1q43; 1q23.1
    Exon count:
    25
    Annotation release Status Assembly Chr Location
    109.20210514 current GRCh38.p13 (GCF_000001405.39) 1 NC_000001.11 (240774742..241357230, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 1 NC_000001.10 (240938042..241520530, complement)

    Chromosome 1 - NC_000001.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC100506929 Neighboring gene THAP domain containing 12 pseudogene 8 Neighboring gene riboflavin kinase pseudogene 1 Neighboring gene heterogeneous nuclear ribonucleoprotein A1 pseudogene 42 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 2 Neighboring gene microRNA 3123 Neighboring gene Sharpr-MPRA regulatory region 3307 Neighboring gene ribosomal protein L36 pseudogene 6 Neighboring gene uncharacterized LOC105373230 Neighboring gene fumarate hydratase

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    Associated conditions

    Description Tests
    GWAS of Longevity in CHARGE Consortium Confirms APOE and FOXO3 Candidacy.
    GeneReviews: Not available
    Meta-analysis of genome-wide association studies in african americans provides insights into the genetic architecture of type 2 diabetes.
    GeneReviews: Not available
    Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
    GeneReviews: Not available

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables G-protein beta-subunit binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables GTPase activator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables GTPase activity TAS
    Traceable Author Statement
    more info
     
    Component Evidence Code Pubs
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    regulator of G-protein signaling 7
    Names
    regulator of G-protein signaling RGS7
    regulator of G-protein signalling 7

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001282773.2NP_001269702.1  regulator of G-protein signaling 7 isoform 2

      See identical proteins and their annotated locations for NP_001269702.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks three alternate exons and contains another alternate exon compared to variant 1. The resulting isoform (2) lacks an alternate internal segment and has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AF493930, AL365184, AW872845, BC022009, BI547250, DA085997, DA605226, R43370
      Consensus CDS
      CCDS60457.1
      UniProtKB/Swiss-Prot
      P49802
      Related
      ENSP00000341242.2, ENST00000348120.6
      Conserved Domains (4) summary
      smart00224
      Location:203263
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:273393
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:2976
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:74161
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    2. NM_001282775.2NP_001269704.1  regulator of G-protein signaling 7 isoform 3

      See identical proteins and their annotated locations for NP_001269704.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) lacks an alternate exon and contains another alternate exon compared to variant 1. The resulting isoform (3) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AF493931, AW872845, BC022009, BI547250, DA085997, DA605226, R43370
      Consensus CDS
      CCDS60459.1
      UniProtKB/Swiss-Prot
      P49802
      Related
      ENSP00000355521.1, ENST00000366563.5
      Conserved Domains (4) summary
      smart00224
      Location:256316
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:326446
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:113214
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    3. NM_001282778.2NP_001269707.1  regulator of G-protein signaling 7 isoform 4

      See identical proteins and their annotated locations for NP_001269707.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AW872845, AY587875, BC022009, BI547250, DA085997, DA605226, R43370
      Consensus CDS
      CCDS60458.1
      UniProtKB/Swiss-Prot
      P49802
      Related
      ENSP00000355522.1, ENST00000366564.5
      Conserved Domains (3) summary
      smart00224
      Location:256316
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:326446
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    4. NM_001350113.2NP_001337042.1  regulator of G-protein signaling 7 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) contains an alternate exon in its 5' UTR, resulting in use of a downstream start codon, and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR. The resulting isoform (5) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Variants 5 and 6 encode the same protein (isoform 5).
      Source sequence(s)
      AF493931, AL359764, AW872845, BC022009, DA085997, DA605226, R43370
      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    5. NM_001350114.2NP_001337043.1  regulator of G-protein signaling 7 isoform 5

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) contains an alternate exon in its 5' UTR, resulting in use of a downstream start codon, and includes an alternate penultimate exon, compared to variant 1, resulting in a novel 3' coding region and longer 3' UTR. The resulting isoform (5) has a shorter N-terminus and a distinct C-terminus compared to isoform 1. Variants 5 and 6 encode the same protein (isoform 5).
      Source sequence(s)
      AF493931, AL592076, AW872845, BC022009, DA085997, DA605226, R43370
      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    6. NM_001350115.2NP_001337044.1  regulator of G-protein signaling 7 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) contains an alternate exon in its 5' UTR, resulting in use of a downstream start codon, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (6) has a shorter N-terminus and lacks an internal segment compared to isoform 1. Variants 7 and 8 encode the same protein (isoform 6).
      Source sequence(s)
      AF493931, AL359764, AW872845, BC022009, DA085997, DA605226, R43370
      Conserved Domains (3) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    7. NM_001350116.1NP_001337045.1  regulator of G-protein signaling 7 isoform 6

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) differs in its 5' UTR, resulting in use of a downstream start codon, and lacks an alternate in-frame exon in the 3' coding region, compared to variant 1. The resulting isoform (6) has a shorter N-terminus and lacks an internal segment compared to isoform 1. Variants 7 and 8 encode the same protein (isoform 6).
      Source sequence(s)
      AF493931, AL592076, AW872845, BC022009, DA085997, DA605226, R43370
      Conserved Domains (3) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    8. NM_001364886.1NP_001351815.1  regulator of G-protein signaling 7 isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (9) encodes the longest isoform (7).
      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Related
      ENSP00000404399.2, ENST00000440928.6
      Conserved Domains (4) summary
      smart00224
      Location:256316
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:326446
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:113214
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    9. NM_001374806.1NP_001361735.1  regulator of G-protein signaling 7 isoform 8

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      smart00224
      Location:239299
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:309429
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:2999
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:96197
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    10. NM_001374807.1NP_001361736.1  regulator of G-protein signaling 7 isoform 9

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      smart00224
      Location:239299
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:309429
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:2999
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:96197
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    11. NM_001374808.1NP_001361737.1  regulator of G-protein signaling 7 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    12. NM_001374809.1NP_001361738.1  regulator of G-protein signaling 7 isoform 10

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (3) summary
      smart00224
      Location:163223
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:233353
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      pfam18148
      Location:71121
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    13. NM_001374810.1NP_001361739.1  regulator of G-protein signaling 7 isoform 11

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (3) summary
      smart00224
      Location:163223
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:233353
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      pfam18148
      Location:71121
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    14. NM_001374811.1NP_001361740.1  regulator of G-protein signaling 7 isoform 13

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      smart00224
      Location:203263
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:273393
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:2976
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:74161
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    15. NM_001374812.1NP_001361741.1  regulator of G-protein signaling 7 isoform 12

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      smart00224
      Location:231291
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:301421
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:113203
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    16. NM_001374813.1NP_001361742.1  regulator of G-protein signaling 7 isoform 14

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (2) summary
      smart00224
      Location:85145
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:155275
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
    17. NM_001374814.1NP_001361743.1  regulator of G-protein signaling 7 isoform 15

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      smart00224
      Location:203263
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:273393
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:2976
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:74161
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    18. NM_001374815.1NP_001361744.1  regulator of G-protein signaling 7 isoform 16

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      cd08738
      Location:289409
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:113214
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
      pfam00631
      Location:256282
      G-gamma; GGL domain
    19. NM_001374816.1NP_001361745.1  regulator of G-protein signaling 7 isoform 17

      Status: VALIDATED

      Source sequence(s)
      AL359764, AL365184, AL512307, AL590682
      Conserved Domains (4) summary
      cd08738
      Location:289409
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:113214
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
      cl00069
      Location:256282
      GGL; G protein gamma subunit-like motifs, the alpha-helical G-gamma chain dimerizes with the G-beta propeller subunit as part of the heterotrimeric G-protein complex; involved in signal transduction via G-protein-coupled receptors
    20. NM_002924.6NP_002915.3  regulator of G-protein signaling 7 isoform 1

      See identical proteins and their annotated locations for NP_002915.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform 1.
      Source sequence(s)
      AL365184, AW872845, BC022009, BI547250, DA605226, R43370
      Consensus CDS
      CCDS31071.1
      UniProtKB/Swiss-Prot
      P49802
      Related
      ENSP00000355523.1, ENST00000366565.5
      Conserved Domains (3) summary
      smart00224
      Location:256316
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:326446
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:29116
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20210514

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000001.11 Reference GRCh38.p13 Primary Assembly

      Range
      240774742..241357230 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017002009.1XP_016857498.1  regulator of G-protein signaling 7 isoform X7

      Conserved Domains (3) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
    2. XM_017002013.1XP_016857502.1  regulator of G-protein signaling 7 isoform X10

    3. XM_017002001.2XP_016857490.1  regulator of G-protein signaling 7 isoform X2

    4. XM_017002002.2XP_016857491.1  regulator of G-protein signaling 7 isoform X3

      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    5. XM_017002005.2XP_016857494.1  regulator of G-protein signaling 7 isoform X6

      UniProtKB/TrEMBL
      B7Z257
      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    6. XM_011544246.3XP_011542548.1  regulator of G-protein signaling 7 isoform X3

      See identical proteins and their annotated locations for XP_011542548.1

      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    7. XM_006711800.4XP_006711863.1  regulator of G-protein signaling 7 isoform X3

      See identical proteins and their annotated locations for XP_006711863.1

      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    8. XM_011544247.3XP_011542549.1  regulator of G-protein signaling 7 isoform X3

      See identical proteins and their annotated locations for XP_011542549.1

      Conserved Domains (4) summary
      smart00224
      Location:230290
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:300420
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      cd04450
      Location:390
      DEP_RGS7-like; DEP (Dishevelled, Egl-10, and Pleckstrin) domain found in RGS (regulator of G-protein signaling) proteins of the subfamily R7. This subgroup contains RGS7, RGS6, RGS9 and RGS11. They share a common domain architecture, containing, beside the RGS domain, ...
      pfam18148
      Location:87188
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
    9. XM_017002011.2XP_016857500.1  regulator of G-protein signaling 7 isoform X8

      Conserved Domains (4) summary
      smart00224
      Location:172232
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:242362
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      pfam18148
      Location:29130
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
      cl02442
      Location:132
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
    10. XM_017002012.2XP_016857501.1  regulator of G-protein signaling 7 isoform X9

      UniProtKB/TrEMBL
      B7Z223
      Conserved Domains (4) summary
      smart00224
      Location:172232
      GGL; G protein gamma subunit-like motifs
      cd08738
      Location:242362
      RGS_RGS7; Regulator of G protein signaling (RGS) domain found in the RGS7 protein
      pfam18148
      Location:29130
      RGS_DHEX; Regulator of G-protein signalling DHEX domain
      cl02442
      Location:132
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
    Support Center