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    SPRYD7 SPRY domain containing 7 [ Homo sapiens (human) ]

    Gene ID: 57213, updated on 8-Jan-2019

    Summary

    Official Symbol
    SPRYD7provided by HGNC
    Official Full Name
    SPRY domain containing 7provided by HGNC
    Primary source
    HGNC:HGNC:14297
    See related
    Ensembl:ENSG00000123178 MIM:607866
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    CLLD6; C13orf1
    Expression
    Ubiquitous expression in lung (RPKM 5.0), brain (RPKM 4.9) and 25 other tissues See more
    Orthologs

    Genomic context

    See SPRYD7 in Genome Data Viewer
    Location:
    13q14.2
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    109 current GRCh38.p12 (GCF_000001405.38) 13 NC_000013.11 (49912702..49936501, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 13 NC_000013.10 (50486842..50510626, complement)

    Chromosome 13 - NC_000013.11Genomic Context describing neighboring genes Neighboring gene CTAGE family member 10, pseudogene Neighboring gene RNY4 pseudogene 9 Neighboring gene deleted in lymphocytic leukemia 2 Neighboring gene microRNA 3613 Neighboring gene tripartite motif containing 13 Neighboring gene potassium channel regulator

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 

    General protein information

    Preferred Names
    SPRY domain-containing protein 7
    Names
    CLL deletion region gene 6 protein
    chronic lymphocytic leukemia deletion region gene 6 protein
    epididymis secretory sperm binding protein

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001127482.2NP_001120954.1  SPRY domain-containing protein 7 isoform 2

      See identical proteins and their annotated locations for NP_001120954.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) omits an in-frame coding exon resulting in a shorter protein isoform (2) compared to isoform 1.
      Source sequence(s)
      AF334405, AK290576, BM684781, DA485722, DN992366
      Consensus CDS
      CCDS45046.1
      UniProtKB/Swiss-Prot
      Q5W111
      Related
      ENSP00000367437.2, ENST00000378195.6
      Conserved Domains (1) summary
      cd12880
      Location:8157
      SPRYD7; SPRY domain-containing protein 7
    2. NM_020456.4NP_065189.1  SPRY domain-containing protein 7 isoform 1

      See identical proteins and their annotated locations for NP_065189.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes the predicted full length protein isoform (1).
      Source sequence(s)
      AF055016, AF334405, BC022519, BM684781, DN992366
      Consensus CDS
      CCDS9422.1
      UniProtKB/Swiss-Prot
      Q5W111
      UniProtKB/TrEMBL
      A0A024RDT6
      Related
      ENSP00000354774.3, ENST00000361840.7
      Conserved Domains (1) summary
      cd12880
      Location:35196
      SPRYD7; SPRY domain-containing protein 7

    RNA

    1. NR_023351.2 RNA Sequence

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) omits two coding exons resulting in a frameshift and premature stop codon. The transcript is predicted to be a candidate for nonsense-mediated decay.
      Source sequence(s)
      AF334405, BM684781, DA388141, DA485722, DN992366

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p12 Primary Assembly

    Genomic

    1. NC_000013.11 Reference GRCh38.p12 Primary Assembly

      Range
      49912702..49936501 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017020677.1XP_016876166.1  SPRY domain-containing protein 7 isoform X1

    RNA

    1. XR_001749634.1 RNA Sequence

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