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    myb.S MYB proto-oncogene, transcription factor S homeolog [ Xenopus laevis (African clawed frog) ]

    Gene ID: 398039, updated on 11-Apr-2024

    Summary

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    Official Symbol
    myb.S
    Official Full Name
    MYB proto-oncogene, transcription factor S homeolog
    Primary source
    Xenbase:XB-GENE-867566
    Locus tag
    XELAEV_18029186mg
    See related
    EnsemblRapid:ENSXLAG00005004370
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Xenopus laevis
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Amphibia; Batrachia; Anura; Pipoidea; Pipidae; Xenopodinae; Xenopus; Xenopus
    Also known as
    myb; cmyb; xmyb; c-myb
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    Genomic context

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    Location:
    chromosome: 5S
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    101 current Xenopus_laevis_v10.1 (GCF_017654675.1) 5S NC_054380.1 (61034338..61056742, complement)
    100 previous assembly Xenopus_laevis_v2 (GCF_001663975.1) 5S NC_030733.1 (53332502..53353660)

    Chromosome 5S - NC_054380.1Genomic Context describing neighboring genes Neighboring gene phosphodiesterase 7B S homeolog Neighboring gene jouberin-like Neighboring gene uncharacterized LOC121394234 Neighboring gene HBS1-like protein

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Characterization and expression of the Xenopus c-Myb homolog. Amaravadi L, et al. Oncogene, 1994 Mar. PMID 7509053

    GeneRIFs: Gene References Into Functions

    General gene information

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    Homology

    Gene Ontology Provided by Xenbase

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
    Inferred from Electronic Annotation
    more info
    		  
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    acts_upstream_of_or_within mitotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within positive regulation of transcription by RNA polymerase II IEA
    Inferred from Electronic Annotation
    more info
    		  
    acts_upstream_of_or_within regulation of DNA-templated transcription IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
    		  

    General protein information

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    Preferred Names
    transcriptional activator Myb
    Names
    DNA-binding transcriptional regulator
    v-myb avian myeloblastosis viral oncogene homolog S homeolog
    v-myb myeloblastosis viral oncogene homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001088299.3 → NP_001081768.2  transcriptional activator Myb

      Status: VALIDATED

      Source sequence(s)
      LYTH01112352
      UniProtKB/Swiss-Prot
      Q08759
      Related
      ENSXLAP00005013062.1, ENSXLAT00005013242.1

    RefSeqs of Annotated Genomes: Xenopus laevis Annotation Release 101 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference Xenopus_laevis_v10.1 Primary Assembly

    Genomic

    1. NC_054380.1 Reference Xenopus_laevis_v10.1 Primary Assembly

      Range
      61034338..61056742 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_041563918.1 → XP_041419852.1  transcriptional activator Myb isoform X2

      UniProtKB/Swiss-Prot
      Q08759
      UniProtKB/TrEMBL
      A0A8J1KR96
      Conserved Domains (2) summary
      PLN03212
      Location:89 → 194
      PLN03212; Transcription repressor MYB5; Provisional
      pfam13921
      Location:40 → 100
      Myb_DNA-bind_6; Myb-like DNA-binding domain

    2. XM_041563917.1 → XP_041419851.1  transcriptional activator Myb isoform X1

      UniProtKB/Swiss-Prot
      Q08759
      UniProtKB/TrEMBL
      A0A8J1KRC0
      Related
      ENSXLAP00005013065.1, ENSXLAT00005013245.1
      Conserved Domains (2) summary
      PLN03212
      Location:91 → 196
      PLN03212; Transcription repressor MYB5; Provisional
      pfam13921
      Location:42 → 102
      Myb_DNA-bind_6; Myb-like DNA-binding domain

    3. XM_041563919.1 → XP_041419853.1  transcriptional activator Myb isoform X3

      UniProtKB/Swiss-Prot
      Q08759
      UniProtKB/TrEMBL
      A0A1L8G2N9, A0A974CR21
      Related
      ENSXLAP00005013067.1, ENSXLAT00005013247.1
      Conserved Domains (4) summary
      PLN03091
      Location:88 → 203
      PLN03091; hypothetical protein; Provisional
      pfam13921
      Location:42 → 102
      Myb_DNA-bind_6; Myb-like DNA-binding domain
      pfam07988
      Location:260 → 304
      LMSTEN; LMSTEN motif
      pfam09316
      Location:388 → 550
      Cmyb_C; C-myb, C-terminal
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q08759.1 GenPept UniProtKB/Swiss-Prot:Q08759

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