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    ANXA2 annexin A2 [ Gallus gallus (chicken) ]

    Gene ID: 396297, updated on 3-Dec-2024

    Summary

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    Official Symbol
    ANXA2provided by CGNC
    Official Full Name
    annexin A2provided by CGNC
    Primary source
    CGNC:49740
    See related
    Ensembl:ENSGALG00010024693
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Gallus gallus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Galloanserae; Galliformes; Phasianidae; Phasianinae; Gallus
    Also known as
    ANX2; ANXA2P2
    Orthologs
    human mouse all
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    Genomic context

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    See ANXA2 in Genome Data Viewer
    Location:
    chromosome: 10
    Exon count:
    18
    Annotation release Status Assembly Chr Location
    106 current bGalGal1.mat.broiler.GRCg7b (GCF_016699485.2) 10 NC_052541.1 (5093832..5126129)
    106 current bGalGal1.pat.whiteleghornlayer.GRCg7w (GCF_016700215.2) 10 NC_052582.1 (4967961..5000301)

    Chromosome 10 - NC_052541.1Genomic Context describing neighboring genes Neighboring gene RAR related orphan receptor A Neighboring gene uncharacterized LOC121111661 Neighboring gene uncharacterized LOC107052149 Neighboring gene uncharacterized LOC124417124 Neighboring gene uncharacterized LOC121111665 Neighboring gene interactor of little elongation complex ELL subunit 2 Neighboring gene uncharacterized LOC121113486 Neighboring gene forkhead box B1

    Genomic regions, transcripts, and products

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    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Identification of novel viral receptors with cell line expressing viral receptor-binding protein. Mei M, et al. Sci Rep, 2015 Jan 21. PMID 25604889, Free PMC Article
    2. Annexin II-mediated plasmin generation activates TGF-beta3 during epithelial-mesenchymal transformation in the developing avian heart. Krishnan S, et al. Dev Biol, 2004 Jan 1. PMID 14697359
    3. The roles of annexins and types II and X collagen in matrix vesicle-mediated mineralization of growth plate cartilage. Kirsch T, et al. J Biol Chem, 2000 Nov 10. PMID 10956650
    4. p36, the major cytoplasmic substrate of src tyrosine protein kinase, binds to its p11 regulatory subunit via a short amino-terminal amphiphatic helix. Johnsson N, et al. EMBO J, 1988 Aug. PMID 2973411, Free PMC Article
    5. The cDNA sequence of chicken annexin II. Gerke V, et al. Nucleic Acids Res, 1990 Jul 25. PMID 2143014, Free PMC Article

    See all (11) citations in PubMed

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?
    1. These results indicate, for the first time, that binding to Anx2 is beneficial for infectious bursal disease virus infection.
      Title: Binding chicken Anx2 is beneficial for infection with infectious bursal disease virus.
    2. chicken Annexin A2 (chANXA2) as a novel receptor for retrovirus ALV-J (avian leukosis virus subgroup J).
      Title: Identification of novel viral receptors with cell line expressing viral receptor-binding protein.
    Submit: New GeneRIF Correction

    General gene information

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    Homology

    Gene Ontology Provided by RefSeq

    Function Evidence Code Pubs
    enables calcium ion binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables calcium-dependent phospholipid binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables cytoskeletal protein binding IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    enables phospholipase inhibitor activity IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    annexin A2
    Names
    PAP-IV
    annexin A2 pseudogene 2
    annexin II
    annexin-2
    calpactin I heavy chain
    calpactin-1 heavy chain
    chromobindin-8
    lipocortin II
    p36
    placental anticoagulant protein IV
    protein I

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_205351.2 → NP_990682.1  annexin A2

      See identical proteins and their annotated locations for NP_990682.1

      Status: PROVISIONAL

      Source sequence(s)
      JAENSK010000245
      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99
      Related
      ENSGALP00010037051.1, ENSGALT00010060292.1
      Conserved Domains (1) summary
      pfam00191
      Location:109 → 174
      Annexin

    RefSeqs of Annotated Genomes: Gallus gallus Annotation Release 106 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

    Genomic

    1. NC_052541.1 Reference bGalGal1.mat.broiler.GRCg7b Primary Assembly

      Range
      5093832..5126129
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_040706203.2 → XP_040562137.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99
      Conserved Domains (1) summary
      pfam00191
      Location:109 → 174
      Annexin

    2. XM_015278763.4 → XP_015134249.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99
      Conserved Domains (1) summary
      pfam00191
      Location:109 → 174
      Annexin

    3. XM_025153801.3 → XP_025009569.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99
      Related
      ENSGALP00010037063.1, ENSGALT00010060304.1
      Conserved Domains (1) summary
      pfam00191
      Location:109 → 174
      Annexin

    4. XM_025153803.3 → XP_025009571.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99
      Conserved Domains (1) summary
      pfam00191
      Location:109 → 174
      Annexin

    Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

    Genomic

    1. NC_052582.1 Alternate bGalGal1.pat.whiteleghornlayer.GRCg7w

      Range
      4967961..5000301
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_046924548.1 → XP_046780504.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99

    2. XM_046924552.1 → XP_046780508.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99

    3. XM_046924549.1 → XP_046780505.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99

    4. XM_046924553.1 → XP_046780509.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99

    5. XM_046924550.1 → XP_046780506.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99

    6. XM_046924551.1 → XP_046780507.1  annexin A2 isoform X1

      UniProtKB/Swiss-Prot
      P17785
      UniProtKB/TrEMBL
      A0A1C9KD18, A0A8V0ZZ99
    Nucleotide Protein Strain
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    P17785.2 GenPept UniProtKB/Swiss-Prot:P17785

    Gene LinkOut

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