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    Gja1 gap junction protein, alpha 1 [ Rattus norvegicus (Norway rat) ]

    Gene ID: 24392, updated on 16-Apr-2024

    Summary

    Official Symbol
    Gja1provided by RGD
    Official Full Name
    gap junction protein, alpha 1provided by RGD
    Primary source
    RGD:2690
    See related
    Ensembl:ENSRNOG00000000805 AllianceGenome:RGD:2690
    Gene type
    protein coding
    RefSeq status
    PROVISIONAL
    Organism
    Rattus norvegicus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
    Also known as
    Cx43; Cxnk1
    Summary
    Enables connexin binding activity; gap junction channel activity; and protein domain specific binding activity. Involved in several processes, including blood vessel diameter maintenance; negative regulation of cell population proliferation; and reproductive structure development. Located in several cellular components, including endosome; fascia adherens; and gap junction. Part of connexin complex. Used to study Parkinsonism; amnestic disorder; high grade glioma; and myocardial infarction. Biomarker of several diseases, including artery disease (multiple); autoimmune thyroiditis; borna disease; ischemia (multiple); and tongue squamous cell carcinoma. Human ortholog(s) of this gene implicated in several diseases, including autosomal recessive craniometaphyseal dysplasia; congenital heart disease (multiple); erythrokeratodermia variabilis (multiple); oculodentodigital dysplasia; and palmoplantar keratoderma and congenital alopecia 1. Orthologous to human GJA1 (gap junction protein alpha 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Biased expression in Heart (RPKM 726.0), Adrenal (RPKM 573.0) and 9 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Gja1 in Genome Data Viewer
    Location:
    20q11
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2024_02 current GRCr8 (GCF_036323735.1) 20 NC_086038.1 (36302490..36315010)
    RS_2023_06 previous assembly mRatBN7.2 (GCF_015227675.2) 20 NC_051355.1 (35756007..35768481)
    106 previous assembly Rnor_6.0 (GCF_000001895.5) 20 NC_005119.4 (37876650..37889097)

    Chromosome 20 - NC_086038.1Genomic Context describing neighboring genes Neighboring gene TBC1 domain family, member 32 Neighboring gene male-specific lethal 3-like 2 Neighboring gene inactive serine/threonine-protein kinase VRK3 pseudogene Neighboring gene lactate dehydrogenase A, pseudogene 19 Neighboring gene uncharacterized LOC108349074 Neighboring gene ribosomal protein L15, pseudogene 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: A rat RNA-Seq transcriptomic BodyMap across 11 organs and 4 developmental stages
    • Description: 320 RNA samples isolated from 11 organs (adrenal gland, brain, heart, kidney, liver, lung, muscle, spleen, thymus, and testes or uterus) from both sexes of Fischer 344 rats across four developmental stages (2-, 6-, 21-, and 104-weeks-old)
    • BioProject: PRJNA238328
    • Publication: PMID 24510058
    • Analysis date: Mon Jun 6 17:44:12 2016

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • MGC93610

    Gene Ontology Provided by RGD

    Function Evidence Code Pubs
    enables PDZ domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables SH3 domain binding EXP
    Inferred from Experiment
    more info
    PubMed 
    enables SH3 domain binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables SH3 domain binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables alpha-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables beta-catenin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables beta-tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables connexin binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables disordered domain specific binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables efflux transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables gap junction channel activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables gap junction channel activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables gap junction channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables gap junction channel activity involved in cell communication by electrical coupling ISO
    Inferred from Sequence Orthology
    more info
     
    enables gap junction hemi-channel activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables gap junction hemi-channel activity ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables glutathione transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables monoatomic ion transmembrane transporter activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein domain specific binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables protein tyrosine kinase binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables scaffold protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables signaling receptor binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables tubulin binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables tubulin binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    Process Evidence Code Pubs
    involved_in ATP transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in T cell activation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in T cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within adult heart development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within atrial ventricular junction remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within blood vessel morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bone development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bone development ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in bone remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in bone remodeling ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within cardiac conduction ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell communication by chemical coupling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell communication by electrical coupling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    acts_upstream_of_or_within cell communication by electrical coupling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell communication by electrical coupling ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within cell-cell junction organization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell signaling IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in cell-cell signaling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in cell-cell signaling IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell-cell signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell-cell signaling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to amyloid-beta ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to mechanical stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to pH ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cellular response to parathyroid hormone stimulus IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in cellular response to platelet-derived growth factor stimulus ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in chronic inflammatory response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within columnar/cuboidal epithelial cell maturation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in decidualization IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within embryonic digit morphogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within embryonic heart tube development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in endothelium development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in epididymis development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in establishment of mitotic spindle orientation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in export across plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in gap junction assembly TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in glutamate secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in glutathione transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in heart development IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in heart development IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in heart development IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    acts_upstream_of_or_within heart development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in heart development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within heart looping ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within in utero embryonic development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within lens development in camera-type eye ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in maintenance of protein localization in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in male gonad development ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule-based transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in microtubule-based transport ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    acts_upstream_of_or_within milk ejection reflex ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in monoatomic ion transmembrane transport ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of DNA biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of cardiac muscle cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of cell growth IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of cell growth ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of cell population proliferation IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of endothelial cell proliferation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of gonadotropin secretion ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in negative regulation of trophoblast cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within neuroblast migration ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within neuron migration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in neuron projection morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within osteoblast differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of behavioral fear response IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of canonical NF-kappaB signal transduction ISO
    Inferred from Sequence Orthology
    more info
    PubMed 
    involved_in positive regulation of cell communication by chemical coupling IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of cold-induced thermogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of cold-induced thermogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    involved_in positive regulation of cytosolic calcium ion concentration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of establishment of Sertoli cell barrier IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of glomerular filtration IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of insulin secretion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of meiotic nuclear division IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of mesodermal cell differentiation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of morphogenesis of an epithelium ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of protein catabolic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in positive regulation of smooth muscle cell chemotaxis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of stem cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within positive regulation of striated muscle tissue development ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of positive regulation of vascular associated smooth muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in positive regulation of vasoconstriction IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of actin filament organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of atrial cardiac muscle cell membrane depolarization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of bicellular tight junction assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within regulation of bone mineralization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of bone remodeling ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in regulation of calcium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of cell communication by electrical coupling IDA
    Inferred from Direct Assay
    more info
    PubMed 
    acts_upstream_of_or_within regulation of heart contraction ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of ventricular cardiac muscle cell membrane depolarization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of ventricular cardiac muscle cell membrane repolarization ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to estradiol IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to fluid shear stress IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to glucose IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to ischemia IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to ischemia ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in response to lipopolysaccharide IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to pH IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in response to peptide hormone IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to retinoic acid IEP
    Inferred from Expression Pattern
    more info
    PubMed 
    involved_in response to wounding ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in signal transduction ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within skeletal muscle tissue regeneration ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in spermatogenesis ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in spermatogenesis ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in transmembrane transport IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in transmembrane transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vascular transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in vasodilation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in xenobiotic transport ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
     
    located_in Golgi-associated vesicle membrane TAS
    Traceable Author Statement
    more info
     
    located_in apical plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in apical plasma membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell contact zone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    part_of connexin complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of connexin complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of connexin complex IEA
    Inferred from Electronic Annotation
    more info
     
    part_of connexin complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    part_of connexin complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in contractile muscle fiber ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in early endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    located_in endoplasmic reticulum membrane TAS
    Traceable Author Statement
    more info
     
    located_in endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in fascia adherens IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in fascia adherens ISO
    Inferred from Sequence Orthology
    more info
     
    located_in gap junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in gap junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intercalated disc IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in intercalated disc ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intermediate filament ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle ISO
    Inferred from Sequence Orthology
    more info
     
    located_in late endosome IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lateral plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in lysosome ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane raft IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane raft ISO
    Inferred from Sequence Orthology
    more info
     
    located_in mitochondrial outer membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitochondrion ISO
    Inferred from Sequence Orthology
    more info
     
    located_in multivesicular body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in plasma membrane IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
    PubMed 
    part_of protein-containing complex IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    located_in tight junction ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    gap junction alpha-1 protein
    Names
    connexin 43
    connexin k1
    gap junction 43 kDa heart protein
    gap junction membrane channel protein alpha 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_012567.2NP_036699.1  gap junction alpha-1 protein

      See identical proteins and their annotated locations for NP_036699.1

      Status: PROVISIONAL

      Source sequence(s)
      AY324140
      UniProtKB/Swiss-Prot
      P08050, Q53ZE1
      UniProtKB/TrEMBL
      A0A654ICE6, A0A8L2UHE4
      Related
      ENSRNOP00000093256.1, ENSRNOT00000100494.1
      Conserved Domains (2) summary
      pfam00029
      Location:3233
      Connexin
      pfam03508
      Location:293312
      Connexin43; Gap junction alpha-1 protein (Cx43)

    RefSeqs of Annotated Genomes: GCF_036323735.1-RS_2024_02

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCr8

    Genomic

    1. NC_086038.1 Reference GRCr8

      Range
      36302490..36315010
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_039098413.2XP_038954341.1  gap junction alpha-1 protein isoform X1

      UniProtKB/Swiss-Prot
      P08050, Q53ZE1
      UniProtKB/TrEMBL
      A0A654ICE6, A0A8L2UHE4
      Conserved Domains (2) summary
      pfam00029
      Location:3233
      Connexin
      pfam03508
      Location:293312
      Connexin43; Gap junction alpha-1 protein (Cx43)
    2. XM_063278953.1XP_063135023.1  gap junction alpha-1 protein isoform X1

      UniProtKB/Swiss-Prot
      P08050, Q53ZE1
      UniProtKB/TrEMBL
      A0A654ICE6
    3. XM_063278954.1XP_063135024.1  gap junction alpha-1 protein isoform X1

      UniProtKB/Swiss-Prot
      P08050, Q53ZE1
      UniProtKB/TrEMBL
      A0A654ICE6