Format

Send to:

Choose Destination
    • Showing Current items.

    Cited2 Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2 [ Mus musculus (house mouse) ]

    Gene ID: 17684, updated on 2-Oct-2018

    Summary

    Official Symbol
    Cited2provided by MGI
    Official Full Name
    Cbp/p300-interacting transactivator, with Glu/Asp-rich carboxy-terminal domain, 2provided by MGI
    Primary source
    MGI:MGI:1306784
    See related
    Ensembl:ENSMUSG00000039910
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mrg1; Msg2; p35srj; AI835299; ER154-like
    Expression
    Ubiquitous expression in placenta adult (RPKM 108.8), ovary adult (RPKM 76.4) and 28 other tissues See more
    Orthologs

    Genomic context

    See Cited2 in Genome Data Viewer
    Location:
    10; 10 A2
    Exon count:
    2
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (17723228..17725674)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (17443034..17445480)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 20125 Neighboring gene ribosomal protein L7A pseudogene Neighboring gene predicted gene, 32543 Neighboring gene predicted gene, 32656 Neighboring gene predicted gene 20655 Neighboring gene taxilin beta Neighboring gene chromodomain protein, Y chromosome-like pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (11)  1 citation
    • Chemically induced (ENU) (1) 

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    DNA-binding transcription factor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    LBD domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    RNA polymerase II activating transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    SMAD binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    chromatin binding IDA
    Inferred from Direct Assay
    more info
    PubMed 
    histone acetyltransferase binding ISO
    Inferred from Sequence Orthology
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    transcription coactivator activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    transcription coactivator activity ISO
    Inferred from Sequence Orthology
    more info
     
    transcription coactivator activity ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    transcription coregulator activity TAS
    Traceable Author Statement
    more info
    PubMed 
    transcription corepressor activity ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    adrenal cortex formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    adrenal gland development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    blood vessel development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    bone morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT branching involved in ureteric bud morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cardiac neural crest cell development involved in heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cardiac septum morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    central nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cranial nerve morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    decidualization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    determination of heart left/right asymmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    determination of left/right symmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic camera-type eye morphogenesis IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    embryonic heart tube left/right pattern formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic placenta development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    embryonic process involved in female pregnancy IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    endocardial cushion development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    erythrocyte development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    granulocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    heart development ISO
    Inferred from Sequence Orthology
    more info
     
    heart development ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    heart looping IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    hematopoietic progenitor cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    in utero embryonic development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    NOT kidney development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    left/right axis specification IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    lens morphogenesis in camera-type eye IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    leukocyte differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    liver development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    male gonad development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    NOT morphogenesis of an epithelium IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    negative regulation of apoptotic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    negative regulation of cardiac muscle cell proliferation ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of cell migration ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription from RNA polymerase II promoter in response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    negative regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    neural tube closure IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    neural tube formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    nodal signaling pathway involved in determination of lateral mesoderm left/right asymmetry IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    outflow tract morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    peripheral nervous system development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell cycle IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of cell-cell adhesion IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of gene expression ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of male gonad development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of peroxisome proliferator activated receptor signaling pathway ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    positive regulation of transcription by RNA polymerase II ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transcription, DNA-templated IDA
    Inferred from Direct Assay
    more info
    PubMed 
    positive regulation of transcription, DNA-templated ISO
    Inferred from Sequence Orthology
    more info
     
    positive regulation of transforming growth factor beta receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pulmonary artery morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of animal organ formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    regulation of transcription by RNA polymerase II IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of transcription, DNA-templated TAS
    Traceable Author Statement
    more info
    PubMed 
    response to estrogen ISO
    Inferred from Sequence Orthology
    more info
     
    response to fluid shear stress ISO
    Inferred from Sequence Orthology
    more info
     
    response to hypoxia ISO
    Inferred from Sequence Orthology
    more info
     
    response to hypoxia ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    sex determination IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    sex determination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    skeletal muscle cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spleen development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    thymus development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    thymus development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    transforming growth factor beta receptor signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    trophectodermal cell differentiation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vasculature development IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    vasculature development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    vasculogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ventricular septum development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    ventricular septum morphogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    cytoplasm ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    nuclear chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    nucleus ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    cbp/p300-interacting transactivator 2
    Names
    MSG-related protein 1
    melanocyte specific gene 2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_010828.3NP_034958.2  cbp/p300-interacting transactivator 2

      See identical proteins and their annotated locations for NP_034958.2

      Status: VALIDATED

      Source sequence(s)
      AK133791, BX516616
      Consensus CDS
      CCDS23708.1
      UniProtKB/Swiss-Prot
      O35740
      Related
      ENSMUSP00000038405.7, ENSMUST00000038107.8
      Conserved Domains (1) summary
      pfam04487
      Location:1269
      CITED; CITED

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      17723228..17725674
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
    Support Center