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    Csf2rb colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage) [ Mus musculus (house mouse) ]

    Gene ID: 12983, updated on 4-Feb-2018
    Official Symbol
    Csf2rbprovided by MGI
    Official Full Name
    colony stimulating factor 2 receptor, beta, low-affinity (granulocyte-macrophage)provided by MGI
    Primary source
    MGI:MGI:1339759
    See related
    Ensembl:ENSMUSG00000071713
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Bc; Il3r; AIC2B; Il3rb; Il5rb; CDw131; Il3rb1; Csf2rb1; Csfgmrb; AI848964
    Expression
    Broad expression in mammary gland adult (RPKM 30.9), spleen adult (RPKM 19.6) and 16 other tissues See more
    Orthologs
    Location:
    15 E1; 15 37.36 cM
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 15 NC_000081.6 (78325798..78351001)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (78156420..78181431)

    Chromosome 15 - NC_000081.6Genomic Context describing neighboring genes Neighboring gene neutrophil cytosolic factor 4 Neighboring gene microRNA 7676-1 Neighboring gene colony stimulating factor 2 receptor, beta 2, low-affinity (granulocyte-macrophage) Neighboring gene microRNA 7676-2 Neighboring gene testis expressed 33 Neighboring gene thiosulfate sulfurtransferase, mitochondrial

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    Products Interactant Other Gene Complex Source Pubs Description

    Markers

    Homology

    Clone Names

    • MGC130522

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    cytokine receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    cytokine-mediated signaling pathway IDA
    Inferred from Direct Assay
    more info
    PubMed 
    regulation of cell growth IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    Preferred Names
    cytokine receptor common subunit beta
    Names
    CD131 antigen
    GM-CSF/IL-3/IL-5 receptor common beta subunit
    GM-CSF/IL-3/IL-5 receptor common beta-chain
    beta c
    colony stimulating factor 2 receptor, beta 1, low-affinity (granulocyte-macrophage)
    common beta chain

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001358854.1NP_001345783.1  cytokine receptor common subunit beta precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AL583893
      Conserved Domains (3) summary
      cd00063
      Location:346439
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:250316
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl26464
      Location:551809
      Atrophin-1; Atrophin-1 family
    2. NM_007780.4NP_031806.3  cytokine receptor common subunit beta precursor

      See identical proteins and their annotated locations for NP_031806.3

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AI467222, AK152608, AL583893
      Consensus CDS
      CCDS27612.1
      UniProtKB/Swiss-Prot
      P26955
      Related
      ENSMUSP00000094082.3, ENSMUST00000096355.3
      Conserved Domains (3) summary
      cd00063
      Location:346439
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:250316
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl26464
      Location:551809
      Atrophin-1; Atrophin-1 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000081.6 Reference GRCm38.p4 C57BL/6J

      Range
      78325798..78351001
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006520390.3XP_006520453.1  cytokine receptor common subunit beta isoform X4

      Conserved Domains (2) summary
      cd00063
      Location:346439
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:248327
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    2. XM_006520387.3XP_006520450.1  cytokine receptor common subunit beta isoform X1

      UniProtKB/Swiss-Prot
      P26955
      Conserved Domains (3) summary
      cd00063
      Location:346439
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:250316
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl26464
      Location:551809
      Atrophin-1; Atrophin-1 family
    3. XM_006520388.1XP_006520451.1  cytokine receptor common subunit beta isoform X2

      Conserved Domains (2) summary
      cd00063
      Location:213306
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
      cl21522
      Location:115194
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    4. XM_006520389.1XP_006520452.1  cytokine receptor common subunit beta isoform X3

      Conserved Domains (1) summary
      cd00063
      Location:396
      FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
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