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    OR52R1 olfactory receptor family 52 subfamily R member 1 (gene/pseudogene) [ Homo sapiens (human) ]

    Gene ID: 119695, updated on 21-Dec-2019

    Summary

    Official Symbol
    OR52R1provided by HGNC
    Official Full Name
    olfactory receptor family 52 subfamily R member 1 (gene/pseudogene)provided by HGNC
    Primary source
    HGNC:HGNC:15235
    See related
    Ensembl:ENSG00000279270
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR11-22
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. This olfactory receptor gene is a segregating pseudogene, where some individuals have an allele that encodes a functional olfactory receptor, while other individuals have an allele encoding a protein that is predicted to be non-functional. [provided by RefSeq, Jun 2015]
    Orthologs

    Genomic context

    See OR52R1 in Genome Data Viewer
    Location:
    11p15.4
    Exon count:
    1
    Annotation release Status Assembly Chr Location
    109.20191205 current GRCh38.p13 (GCF_000001405.39) 11 NC_000011.10 (4803433..4804380, complement)
    105 previous assembly GRCh37.p13 (GCF_000001405.25) 11 NC_000011.9 (4824663..4825610, complement)

    Chromosome 11 - NC_000011.10Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 51 subfamily N member 1 pseudogene Neighboring gene olfactory receptor family 52 subfamily Y member 1 pseudogene Neighboring gene olfactory receptor family 51 subfamily F member 2 Neighboring gene olfactory receptor family 51 subfamily A member 8 pseudogene

    Genomic regions, transcripts, and products

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    G protein-coupled receptor activity IEA
    Inferred from Electronic Annotation
    more info
     
    olfactory receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    G protein-coupled receptor signaling pathway IEA
    Inferred from Electronic Annotation
    more info
     
    detection of chemical stimulus involved in sensory perception of smell IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    olfactory receptor 52R1
    Names
    olfactory receptor OR11-22
    olfactory receptor, family 52, subfamily R, member 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001005177.3NP_001005177.3  olfactory receptor 52R1

      See identical proteins and their annotated locations for NP_001005177.3

      Status: VALIDATED

      Source sequence(s)
      AC103710
      UniProtKB/Swiss-Prot
      Q8NGF1
      Related
      ENSP00000485292.1, ENST00000624978.1
      Conserved Domains (2) summary
      pfam00001
      Location:44295
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:34311
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20191205

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000011.10 Reference GRCh38.p13 Primary Assembly

      Range
      4803433..4804380 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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