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    CD300C CD300c molecule [ Homo sapiens (human) ]

    Gene ID: 10871, updated on 22-Sep-2022

    Summary

    Official Symbol
    CD300Cprovided by HGNC
    Official Full Name
    CD300c moleculeprovided by HGNC
    Primary source
    HGNC:HGNC:19320
    See related
    Ensembl:ENSG00000167850 MIM:606786; AllianceGenome:HGNC:19320
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    LIR; CLM-6; CMRF35; IGSF16; CMRF-35; CMRF35A; CMRF-35A; CMRF35A1; CMRF35-A1
    Summary
    The CMRF35 antigen, which was identified by reactivity with a monoclonal antibody, is present on monocytes, neutrophils, and some T and B lymphocytes (Jackson et al., 1992 [PubMed 1349532]).[supplied by OMIM, Mar 2008]
    Expression
    Broad expression in lung (RPKM 2.9), appendix (RPKM 2.6) and 19 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See CD300C in Genome Data Viewer
    Location:
    17q25.1
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    110 current GRCh38.p14 (GCF_000001405.40) 17 NC_000017.11 (74534635..74546115, complement)
    110 current T2T-CHM13v2.0 (GCF_009914755.1) 17 NC_060941.1 (75431594..75436636, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (72537212..72542254, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124904056 Neighboring gene CD300a molecule Neighboring gene uncharacterized LOC107985074 Neighboring gene CD300 molecule like family member b Neighboring gene CD300H molecule (gene/pseudogene) Neighboring gene CD300LD antisense RNA 1 Neighboring gene CD300 molecule like family member d

    Genomic regions, transcripts, and products

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables transmembrane signaling receptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in cellular defense response TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in immune system process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in plasma membrane TAS
    Traceable Author Statement
    more info
     

    General protein information

    Preferred Names
    CMRF35-like molecule 6
    Names
    CD300 antigen-like family member C
    CD300c antigen
    CMRF35 antigen
    CMRF35 leukocyte immunoglobulin-like receptor
    CMRF35A leukocyte immunoglobulin-like receptor
    immunoglobulin superfamily member 16

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_006678.5NP_006669.1  CMRF35-like molecule 6 precursor

      See identical proteins and their annotated locations for NP_006669.1

      Status: VALIDATED

      Source sequence(s)
      AC079325, BC022279, BF508242
      Consensus CDS
      CCDS11701.1
      UniProtKB/Swiss-Prot
      Q08708
      Related
      ENSP00000329507.1, ENST00000330793.2
      Conserved Domains (2) summary
      cd05716
      Location:30119
      Ig_pIgR_like; Immunoglobulin (Ig)-like domain in the polymeric Ig receptor (pIgR) and similar domains
      cl11960
      Location:95183
      Ig; Immunoglobulin domain

    RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 110 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p14 Primary Assembly

      Range
      74534635..74546115 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017024033.3XP_016879522.1  CMRF35-like molecule 6 isoform X1

    2. XM_047435157.1XP_047291113.1  CMRF35-like molecule 6 isoform X2

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791806.1 Reference GRCh38.p14 PATCHES

      Range
      117521..122563 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060941.1 Alternate T2T-CHM13v2.0

      Range
      75431594..75436636 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)