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PRR29 proline rich 29 [ Homo sapiens (human) ]

Gene ID: 92340, updated on 29-Mar-2018

Summary

Official Symbol
PRR29provided by HGNC
Official Full Name
proline rich 29provided by HGNC
Primary source
HGNC:HGNC:25673
See related
Ensembl:ENSG00000224383 Vega:OTTHUMG00000178594
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
C17orf72
Expression
Broad expression in spleen (RPKM 19.8), lung (RPKM 9.2) and 19 other tissues See more
Orthologs

Genomic context

See PRR29 in Genome Data Viewer
Location:
17q23.3
Exon count:
6
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 17 NC_000017.11 (63998351..64004305)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (62075711..62081645)

Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene growth hormone locus control region Neighboring gene CD79b molecule Neighboring gene uncharacterized LOC105371858 Neighboring gene sodium voltage-gated channel alpha subunit 4 Neighboring gene PRR29 antisense RNA 1 Neighboring gene intercellular adhesion molecule 2 Neighboring gene endoplasmic reticulum to nucleus signaling 1 Neighboring gene small nucleolar RNA, C/D box 104 Neighboring gene small nucleolar RNA host gene 25

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Jun 15 11:32:44 2016

General gene information

Markers

Homology

Clone Names

  • FLJ11724, DKFZp761M2312

General protein information

Preferred Names
proline-rich protein 29
NP_001157729.1
NP_001177958.1
NP_001177959.1
NP_001177960.1
XP_005257862.1
XP_011523770.1
XP_011523771.1
XP_016880804.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001164257.1NP_001157729.1  proline-rich protein 29 isoform 2

    See identical proteins and their annotated locations for NP_001157729.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) uses an alternate splice site and includes an additional exon that causes a frameshift in the 3' coding region, compared to variant 1. The resulting isoform (2) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AC005803, AK021786, BC030709, BC045676
    Consensus CDS
    CCDS54158.1
    UniProtKB/Swiss-Prot
    P0C7W0
    Related
    ENSP00000400986.1, OTTHUMP00000259752, ENST00000412177.5, OTTHUMT00000442613
    Conserved Domains (1) summary
    pfam15248
    Location:39107
    DUF4587; Domain of unknown function (DUF4587)
  2. NM_001191029.1NP_001177958.1  proline-rich protein 29 isoform 1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) encodes the longest isoform (1).
    Source sequence(s)
    AC005803, AK302960, BC045676
    Consensus CDS
    CCDS54157.1
    UniProtKB/Swiss-Prot
    P0C7W0
    Related
    ENSP00000396936.3, OTTHUMP00000259751, ENST00000425164.7, OTTHUMT00000442612
    Conserved Domains (1) summary
    pfam15248
    Location:39107
    DUF4587; Domain of unknown function (DUF4587)
  3. NM_001191030.1NP_001177959.1  proline-rich protein 29 isoform 3

    See identical proteins and their annotated locations for NP_001177959.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) uses an alternate in-frame splice site in the 5' coding region, and uses an alternate splice site and includes an additional exon that causes a frameshift in the 3' coding region, compared to variant 1. The resulting isoform (3) has a distinct C-terminus and is shorter than isoform 1.
    Source sequence(s)
    AC005803, BC045676, DC358808
    Consensus CDS
    CCDS58586.1
    UniProtKB/Swiss-Prot
    P0C7W0
    Related
    ENSP00000462097.1, OTTHUMP00000259750, ENST00000579184.5, OTTHUMT00000442611
    Conserved Domains (1) summary
    pfam15248
    Location:32100
    DUF4587; Domain of unknown function (DUF4587)
  4. NM_001191031.1NP_001177960.1  proline-rich protein 29 isoform 4

    See identical proteins and their annotated locations for NP_001177960.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) lacks an alternate exon but includes a different alternate exon that causes a frameshift in the 3' coding region, compared to variant 1. The resulting isoform (4) has a distinct and shorter C-terminus, compared to isoform 1.
    Source sequence(s)
    AC005803, BC045676, DB037384
    Consensus CDS
    CCDS54159.1
    UniProtKB/Swiss-Prot
    P0C7W0
    Related
    ENSP00000463279.1, OTTHUMP00000259748, ENST00000577953.5, OTTHUMT00000442609
    Conserved Domains (1) summary
    pfam15248
    Location:3991
    DUF4587; Domain of unknown function (DUF4587)

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000017.11 Reference GRCh38.p12 Primary Assembly

    Range
    63998351..64004305
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_005257805.4XP_005257862.1  proline-rich protein 29 isoform X2

    See identical proteins and their annotated locations for XP_005257862.1

    Conserved Domains (1) summary
    pfam15248
    Location:39107
    DUF4587; Domain of unknown function (DUF4587)
  2. XM_011525469.1XP_011523771.1  proline-rich protein 29 isoform X4

    See identical proteins and their annotated locations for XP_011523771.1

    UniProtKB/TrEMBL
    B4DG13
    Related
    ENSP00000464103.1, OTTHUMP00000259749, ENST00000582540.5, OTTHUMT00000442610
    Conserved Domains (1) summary
    pfam15248
    Location:157
    DUF4587; Domain of unknown function (DUF4587)
  3. XM_017025315.1XP_016880804.1  proline-rich protein 29 isoform X3

  4. XM_011525468.2XP_011523770.1  proline-rich protein 29 isoform X1

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NR_015354.2: Suppressed sequence

    Description
    NR_015354.2: This RefSeq was permanently suppressed because it is now thought that this gene does encode a protein.
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