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CRISP2 cysteine rich secretory protein 2 [ Homo sapiens (human) ]

Gene ID: 7180, updated on 21-Apr-2019

Summary

Official Symbol
CRISP2provided by HGNC
Official Full Name
cysteine rich secretory protein 2provided by HGNC
Primary source
HGNC:HGNC:12024
See related
Ensembl:ENSG00000124490 MIM:187430
Gene type
protein coding
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
CT36; TPX1; TSP1; GAPDL5; CRISP-2
Expression
Restricted expression toward testis (RPKM 156.0) See more
Orthologs

Genomic context

See CRISP2 in Genome Data Viewer
Location:
6p12.3
Exon count:
14
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 6 NC_000006.12 (49676665..49714198, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 6 NC_000006.11 (49660071..49681911, complement)

Chromosome 6 - NC_000006.12Genomic Context describing neighboring genes Neighboring gene Rh associated glycoprotein Neighboring gene GATA motif-containing MPRA enhancer 217 Neighboring gene cysteine rich secretory protein 3 Neighboring gene phosphoglycerate kinase 2

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC111136

Gene Ontology Provided by GOA

Process Evidence Code Pubs
cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
cysteine-rich secretory protein 2
Names
cancer/testis antigen 36
glyceraldehyde-3-phosphate dehydrogenase-like 5
testicular tissue protein Li 43
testis specific protein 1 (probe H4-1 p3-1)
testis-specific protein TPX-1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001142407.2NP_001135879.1  cysteine-rich secretory protein 2 precursor

    See identical proteins and their annotated locations for NP_001135879.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) differs in the 5' UTR, compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    BC107707, BG718726, DB082240, DB524518
    Consensus CDS
    CCDS4928.1
    UniProtKB/Swiss-Prot
    P16562
    UniProtKB/TrEMBL
    A0A024RD74
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:189243
    Crisp; Crisp
  2. NM_001142408.2NP_001135880.1  cysteine-rich secretory protein 2 precursor

    See identical proteins and their annotated locations for NP_001135880.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (3) differs in the 5' UTR, compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    AK292385, BC022011, DB082240, DB524518
    Consensus CDS
    CCDS4928.1
    UniProtKB/Swiss-Prot
    P16562
    UniProtKB/TrEMBL
    A0A024RD74
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:189243
    Crisp; Crisp
  3. NM_001142417.2NP_001135889.1  cysteine-rich secretory protein 2 precursor

    See identical proteins and their annotated locations for NP_001135889.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (4) differs in the 5' UTR, compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    DB082240, DB459032, DB524518, M25532
    Consensus CDS
    CCDS4928.1
    UniProtKB/Swiss-Prot
    P16562
    UniProtKB/TrEMBL
    A0A024RD74
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:189243
    Crisp; Crisp
  4. NM_001142435.2NP_001135907.1  cysteine-rich secretory protein 2 precursor

    See identical proteins and their annotated locations for NP_001135907.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (5) differs in the 5' UTR, compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    BI831679, BM552843, DB082240, DB445739, DB524518
    Consensus CDS
    CCDS4928.1
    UniProtKB/Swiss-Prot
    P16562
    UniProtKB/TrEMBL
    A0A024RD74
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:189243
    Crisp; Crisp
  5. NM_001261822.1NP_001248751.1  cysteine-rich secretory protein 2 precursor

    See identical proteins and their annotated locations for NP_001248751.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (6) differs in the 5' UTR, compared to variant 1. All variants encode the same protein.
    Source sequence(s)
    BI562149, BP369378, BP369727, DB082240, DB524518
    Consensus CDS
    CCDS4928.1
    UniProtKB/Swiss-Prot
    P16562
    UniProtKB/TrEMBL
    A0A024RD74
    Related
    ENSP00000484609.1, ENST00000616725.4
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:189243
    Crisp; Crisp
  6. NM_003296.4NP_003287.1  cysteine-rich secretory protein 2 precursor

    See identical proteins and their annotated locations for NP_003287.1

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longest transcript. All variants encode the same protein.
    Source sequence(s)
    AY773479, DB524518
    Consensus CDS
    CCDS4928.1
    UniProtKB/Swiss-Prot
    P16562
    UniProtKB/TrEMBL
    A0A024RD74
    Related
    ENSP00000339155.4, ENST00000339139.5
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:189243
    Crisp; Crisp

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000006.12 Reference GRCh38.p12 Primary Assembly

    Range
    49676665..49714198 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_011514843.3XP_011513145.1  cysteine-rich secretory protein 2 isoform X2

    Conserved Domains (1) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
  2. XM_011514842.1XP_011513144.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011513144.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  3. XM_011514841.1XP_011513143.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_011513143.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  4. XM_005249349.1XP_005249406.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005249406.1

    UniProtKB/Swiss-Prot
    P16562
    Related
    ENSP00000482890.1, ENST00000618917.4
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  5. XM_005249350.1XP_005249407.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005249407.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  6. XM_005249351.3XP_005249408.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005249408.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  7. XM_005249352.3XP_005249409.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005249409.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  8. XM_005249356.1XP_005249413.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005249413.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp
  9. XM_005249353.4XP_005249410.1  cysteine-rich secretory protein 2 isoform X1

    See identical proteins and their annotated locations for XP_005249410.1

    UniProtKB/Swiss-Prot
    P16562
    Conserved Domains (2) summary
    cd05383
    Location:35172
    SCP_CRISP; SCP_CRISP: SCP-like extracellular protein domain, CRISP-like sub-family. The wider family of SCP containing proteins includes plant pathogenesis-related protein 1 (PR-1), CRISPs, mammalian cysteine-rich secretory proteins, which combine SCP with a ...
    pfam08562
    Location:224278
    Crisp; Crisp

RNA

  1. XR_926302.3 RNA Sequence

  2. XR_002956300.1 RNA Sequence

  3. XR_002956302.1 RNA Sequence

  4. XR_002956301.1 RNA Sequence

  5. XR_002956303.1 RNA Sequence

  6. XR_926303.2 RNA Sequence

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