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PTPRD protein tyrosine phosphatase receptor type D [ Homo sapiens (human) ]

Gene ID: 5789, updated on 7-Apr-2019

Summary

Official Symbol
PTPRDprovided by HGNC
Official Full Name
protein tyrosine phosphatase receptor type Dprovided by HGNC
Primary source
HGNC:HGNC:9668
See related
Ensembl:ENSG00000153707 MIM:601598
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
HPTP; PTPD; HPTPD; HPTPDELTA; RPTPDELTA
Summary
The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP contains an extracellular region, a single transmembrane segment and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region of this protein is composed of three Ig-like and eight fibronectin type III-like domains. Studies of the similar genes in chicken and fly suggest the role of this PTP is in promoting neurite growth, and regulating neurons axon guidance. Multiple alternatively spliced transcript variants of this gene have been reported. A related pseudogene has been identified on chromosome 5. [provided by RefSeq, Jan 2010]
Expression
Broad expression in brain (RPKM 18.0), kidney (RPKM 8.8) and 14 other tissues See more
Orthologs

Genomic context

See PTPRD in Genome Data Viewer
Location:
9p24.1-p23
Exon count:
49
Annotation release Status Assembly Chr Location
109 current GRCh38.p12 (GCF_000001405.38) 9 NC_000009.12 (8314246..10612841, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 9 NC_000009.11 (8314246..10612723, complement)

Chromosome 9 - NC_000009.12Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC105375971 Neighboring gene VISTA enhancer hs304 Neighboring gene ribosomal protein L18a pseudogene 11 Neighboring gene RNA, U7 small nuclear 185 pseudogene Neighboring gene PTPRD antisense RNA 1 Neighboring gene ribosomal protein S26 pseudogene 3 Neighboring gene RNA, 7SL, cytoplasmic 5, pseudogene Neighboring gene uncharacterized LOC105375972 Neighboring gene PTPRD antisense RNA 2 (head to head) Neighboring gene IMP3 pseudogene 1

Genomic regions, transcripts, and products

Expression

  • Project title: HPA RNA-seq normal tissues
  • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
  • BioProject: PRJEB4337
  • Publication: PMID 24309898
  • Analysis date: Wed Apr 4 07:08:55 2018

Bibliography

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Phenotypes

NHGRI GWAS Catalog

Description
A genome-wide association study and biological pathway analysis of epilepsy prognosis in a prospective cohort of newly treated epilepsy.
NHGRI GWA Catalog
A genome-wide association study identifies susceptibility variants for type 2 diabetes in Han Chinese.
NHGRI GWA Catalog
A genome-wide association study provides evidence for association of chromosome 8p23 (MYP10) and 10q21.1 (MYP15) with high myopia in the French Population.
NHGRI GWA Catalog
A genome-wide meta-analysis of association studies of Cloninger's Temperament Scales.
NHGRI GWA Catalog
Common genetic variation and susceptibility to partial epilepsies: a genome-wide association study.
NHGRI GWA Catalog
Conduct disorder and ADHD: evaluation of conduct problems as a categorical and quantitative trait in the international multicentre ADHD genetics study.
NHGRI GWA Catalog
Genome wide association study (GWAS) of Chagas cardiomyopathy in Trypanosoma cruzi seropositive subjects.
NHGRI GWA Catalog
Genome-wide association and meta-analysis in populations from Starr County, Texas, and Mexico City identify type 2 diabetes susceptibility loci and enrichment for expression quantitative trait loci in top signals.
NHGRI GWA Catalog
Genome-wide association studies identify CHRNA5/3 and HTR4 in the development of airflow obstruction.
NHGRI GWA Catalog
Genome-wide association study identifies novel loci associated with concentrations of four plasma phospholipid fatty acids in the de novo lipogenesis pathway: results from the Cohorts for Heart and Aging Research in Genomic Epidemiology (CHARGE) consortiu
NHGRI GWA Catalog
Genome-wide association study identifies novel restless legs syndrome susceptibility loci on 2p14 and 16q12.1.
NHGRI GWA Catalog
Genome-wide association study in obsessive-compulsive disorder: results from the OCGAS.
NHGRI GWA Catalog
Genome-wide association study of co-occurring anxiety in major depression.
NHGRI GWA Catalog
Genome-Wide Association Study of Primary Dentition Pit-and-Fissure and Smooth Surface Caries.
NHGRI GWA Catalog
Genome-wide association study of the five-factor model of personality in young Korean women.
NHGRI GWA Catalog
Genome-wide meta-analyses identifies seven loci associated with platelet aggregation in response to agonists.
NHGRI GWA Catalog
Genome-wide meta-analysis identifies new susceptibility loci for migraine.
NHGRI GWA Catalog
Genome-wide SNP associations with rubella-specific cytokine responses in measles-mumps-rubella vaccine recipients.
NHGRI GWA Catalog
Novel genetic loci identified for the pathophysiology of childhood obesity in the Hispanic population.
NHGRI GWA Catalog
Parent-of-origin-specific allelic associations among 106 genomic loci for age at menarche.
NHGRI GWA Catalog
PTPRD (protein tyrosine phosphatase receptor type delta) is associated with restless legs syndrome.
NHGRI GWA Catalog

Pathways from BioSystems

  • Neuronal System, organism-specific biosystem (from REACTOME)
    Neuronal System, organism-specific biosystemThe human brain contains at least 100 billion neurons, each with the ability to influence many other cells. Clearly, highly sophisticated and efficient mechanisms are needed to enable communication a...
  • Protein-protein interactions at synapses, organism-specific biosystem (from REACTOME)
    Protein-protein interactions at synapses, organism-specific biosystemSynapses constitute highly specialized sites of asymmetric cell-cell adhesion and intercellular communication. Its formation involves the recruitment of presynaptic and postsynaptic molecules at newl...
  • SALM protein interactions at the synapses, organism-specific biosystem (from REACTOME)
    SALM protein interactions at the synapses, organism-specific biosystemRecruitment of receptors and ion channels to the postsynaptic membrane is the last step in synapse formation. Many of these proteins interact directly or indirectly with postsynaptic density-95 (PSD9...

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Markers

Homology

Clone Names

  • MGC119750, MGC119751, MGC119752, MGC119753

Gene Ontology Provided by GOA

Function Evidence Code Pubs
cell adhesion molecule binding ISS
Inferred from Sequence or Structural Similarity
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
signaling receptor binding ISS
Inferred from Sequence or Structural Similarity
more info
 
transmembrane receptor protein tyrosine phosphatase activity TAS
Traceable Author Statement
more info
PubMed 
Process Evidence Code Pubs
heterophilic cell-cell adhesion via plasma membrane cell adhesion molecules ISS
Inferred from Sequence or Structural Similarity
more info
 
neuron differentiation ISS
Inferred from Sequence or Structural Similarity
more info
 
peptidyl-tyrosine dephosphorylation IEA
Inferred from Electronic Annotation
more info
 
phosphate-containing compound metabolic process NAS
Non-traceable Author Statement
more info
PubMed 
positive regulation of dendrite morphogenesis ISS
Inferred from Sequence or Structural Similarity
more info
 
positive regulation of synapse assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
presynaptic membrane assembly ISS
Inferred from Sequence or Structural Similarity
more info
 
protein dephosphorylation TAS
Traceable Author Statement
more info
PubMed 
regulation of postsynaptic density assembly IEA
Inferred from Electronic Annotation
more info
 
regulation of presynapse assembly EXP
Inferred from Experiment
more info
PubMed 
regulation of presynapse assembly IDA
Inferred from Direct Assay
more info
PubMed 
synaptic membrane adhesion EXP
Inferred from Experiment
more info
PubMed 
synaptic membrane adhesion IDA
Inferred from Direct Assay
more info
PubMed 
synaptic membrane adhesion IMP
Inferred from Mutant Phenotype
more info
PubMed 
trans-synaptic signaling by trans-synaptic complex EXP
Inferred from Experiment
more info
PubMed 
trans-synaptic signaling by trans-synaptic complex IDA
Inferred from Direct Assay
more info
PubMed 
transmembrane receptor protein tyrosine phosphatase signaling pathway TAS
Traceable Author Statement
more info
PubMed 
Component Evidence Code Pubs
extracellular exosome HDA PubMed 
glutamatergic synapse EXP
Inferred from Experiment
more info
PubMed 
glutamatergic synapse IDA
Inferred from Direct Assay
more info
PubMed 
integral component of plasma membrane TAS
Traceable Author Statement
more info
PubMed 
plasma membrane TAS
Traceable Author Statement
more info
 

General protein information

Preferred Names
receptor-type tyrosine-protein phosphatase delta
Names
R-PTP-delta
protein tyrosine phosphatase, receptor type, delta polypeptide
rceptor-type tyrosine-protein phosphatase delta
NP_001035802.1
NP_001164496.1
NP_002830.1
NP_569075.2
NP_569076.2
NP_569077.2
XP_006716880.1
XP_006716886.1
XP_006716888.1
XP_006716890.1
XP_006716895.1
XP_006716896.1
XP_006716897.1
XP_006716898.1
XP_006716900.1
XP_011516294.1
XP_016870447.1
XP_016870448.1
XP_016870449.1
XP_016870450.1
XP_016870451.1
XP_016870452.1
XP_016870453.1
XP_016870454.1
XP_016870455.1
XP_016870456.1
XP_016870457.1
XP_016870458.1
XP_016870459.1
XP_016870460.1
XP_016870461.1
XP_016870462.1
XP_016870463.1
XP_016870464.1
XP_016870465.1
XP_016870466.1
XP_016870467.1
XP_016870468.1
XP_016870469.1
XP_016870470.1
XP_016870471.1
XP_016870472.1
XP_016870473.1
XP_016870474.1
XP_016870475.1
XP_016870476.1
XP_016870477.1
XP_016870478.1
XP_016870479.1
XP_016870480.1
XP_016870481.1
XP_016870482.1
XP_016870483.1
XP_016870484.1
XP_024303393.1
XP_024303395.1

NCBI Reference Sequences (RefSeq)

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

Genomic

  1. NG_033963.1 RefSeqGene

    Range
    5001..2303478
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NM_001040712.2NP_001035802.1  receptor-type tyrosine-protein phosphatase delta isoform 5 precursor

    See identical proteins and their annotated locations for NP_001035802.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (5) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (5) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.
    Source sequence(s)
    AB208869, AL356584, AL445926, AL590397, BM680342, DR001889
    Consensus CDS
    CCDS55288.1
    UniProtKB/TrEMBL
    Q59H90
    Related
    ENSP00000380735.3, ENST00000397611.7
    Conserved Domains (8) summary
    cd05738
    Location:143223
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:247315
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9461201
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132222
    IG_like; Immunoglobulin like
    cd00047
    Location:9721201
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:320409
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  2. NM_001171025.1NP_001164496.1  receptor-type tyrosine-protein phosphatase delta isoform 6 precursor

    See identical proteins and their annotated locations for NP_001164496.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (6) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (6) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.
    Source sequence(s)
    AL445926, AL590397, BC106713, BM680342, DR001889
    Consensus CDS
    CCDS55289.1
    UniProtKB/Swiss-Prot
    P23468
    Related
    ENSP00000380731.3, ENST00000397606.7
    Conserved Domains (8) summary
    cd05738
    Location:143220
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:240308
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9491204
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132219
    IG_like; Immunoglobulin like
    cd00047
    Location:9751204
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:313402
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  3. NM_002839.3NP_002830.1  receptor-type tyrosine-protein phosphatase delta isoform 1 precursor

    See identical proteins and their annotated locations for NP_002830.1

    Status: REVIEWED

    Description
    Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
    Source sequence(s)
    AB211400, AL356584, AL390723, AL445926, BC028038, BM680342
    Consensus CDS
    CCDS43786.1
    UniProtKB/Swiss-Prot
    P23468
    UniProtKB/TrEMBL
    Q2HXI4
    Related
    ENSP00000370593.3, ENST00000381196.8
    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13561611
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13821611
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  4. NM_130391.3NP_569075.2  receptor-type tyrosine-protein phosphatase delta isoform 2 precursor

    See identical proteins and their annotated locations for NP_569075.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (2) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (2) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.
    Source sequence(s)
    AL445926, BC106715, BM680342, DR001889
    Consensus CDS
    CCDS6472.2
    UniProtKB/Swiss-Prot
    P23468
    Related
    ENSP00000417093.1, ENST00000486161.5
    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9491204
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:9751204
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:323412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  5. NM_130392.3NP_569076.2  receptor-type tyrosine-protein phosphatase delta isoform 3 precursor

    See identical proteins and their annotated locations for NP_569076.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (3) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (3) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.
    Source sequence(s)
    AL445926, BC106714, BM680342, DR001889
    Consensus CDS
    CCDS55290.1
    UniProtKB/Swiss-Prot
    P23468
    Related
    ENSP00000347373.5, ENST00000355233.9
    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9501205
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:9761205
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:323412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  6. NM_130393.3NP_569077.2  receptor-type tyrosine-protein phosphatase delta isoform 4 precursor

    See identical proteins and their annotated locations for NP_569077.2

    Status: REVIEWED

    Description
    Transcript Variant: This variant (4) has multiple differences in the coding region, compared to variant 1, resulting in an isoform (4) that is shorter than isoform 1. The 5' UTR of this variant is incomplete because no 5' complete transcripts representing this variant exist, and there are alternate splicing choices in the upstream region.
    Source sequence(s)
    AL445926, AL590397, BC106716, BM680342, DR001889
    Consensus CDS
    CCDS75813.1
    UniProtKB/TrEMBL
    Q3KPI9
    Related
    ENSP00000440515.2, ENST00000537002.5
    Conserved Domains (8) summary
    cd05738
    Location:143220
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:244312
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9401195
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132219
    IG_like; Immunoglobulin like
    cd00047
    Location:9661195
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:317406
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 109

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p12 Primary Assembly

Genomic

  1. NC_000009.12 Reference GRCh38.p12 Primary Assembly

    Range
    8314246..10612841 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017014958.2XP_016870447.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  2. XM_011517992.3XP_011516294.1  receptor-type tyrosine-protein phosphatase delta isoform X22

    See identical proteins and their annotated locations for XP_011516294.1

    UniProtKB/Swiss-Prot
    P23468
    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13561611
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13821611
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  3. XM_017014991.2XP_016870480.1  receptor-type tyrosine-protein phosphatase delta isoform X36

    UniProtKB/Swiss-Prot
    P23468
    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9501205
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:9761205
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:323412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  4. XM_006716835.4XP_006716898.1  receptor-type tyrosine-protein phosphatase delta isoform X42

    See identical proteins and their annotated locations for XP_006716898.1

    UniProtKB/Swiss-Prot
    P23468
    Conserved Domains (8) summary
    cd05738
    Location:143223
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:247315
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9461201
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132222
    IG_like; Immunoglobulin like
    cd00047
    Location:9721201
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:320409
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  5. XM_006716833.4XP_006716896.1  receptor-type tyrosine-protein phosphatase delta isoform X38

    See identical proteins and their annotated locations for XP_006716896.1

    UniProtKB/Swiss-Prot
    P23468
    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9491204
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:9751204
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:323412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  6. XM_006716832.4XP_006716895.1  receptor-type tyrosine-protein phosphatase delta isoform X37

    See identical proteins and their annotated locations for XP_006716895.1

    UniProtKB/Swiss-Prot
    P23468
    Conserved Domains (8) summary
    cd05738
    Location:143220
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:240308
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9491204
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132219
    IG_like; Immunoglobulin like
    cd00047
    Location:9751204
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:313402
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  7. XM_006716837.4XP_006716900.1  receptor-type tyrosine-protein phosphatase delta isoform X45

    See identical proteins and their annotated locations for XP_006716900.1

    UniProtKB/TrEMBL
    Q3KPI9
    Conserved Domains (8) summary
    cd05738
    Location:143220
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:244312
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9401195
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132219
    IG_like; Immunoglobulin like
    cd00047
    Location:9661195
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:317406
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  8. XM_006716817.4XP_006716880.1  receptor-type tyrosine-protein phosphatase delta isoform X6

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13731628
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13991628
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  9. XM_017014965.2XP_016870454.1  receptor-type tyrosine-protein phosphatase delta isoform X4

  10. XM_017014972.2XP_016870461.1  receptor-type tyrosine-protein phosphatase delta isoform X13

  11. XM_017014961.2XP_016870450.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  12. XM_017014960.2XP_016870449.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  13. XM_017014966.2XP_016870455.1  receptor-type tyrosine-protein phosphatase delta isoform X5

  14. XM_017014969.2XP_016870458.1  receptor-type tyrosine-protein phosphatase delta isoform X9

  15. XM_017014974.2XP_016870463.1  receptor-type tyrosine-protein phosphatase delta isoform X15

  16. XM_017014964.2XP_016870453.1  receptor-type tyrosine-protein phosphatase delta isoform X3

  17. XM_017014970.2XP_016870459.1  receptor-type tyrosine-protein phosphatase delta isoform X10

  18. XM_017014979.2XP_016870468.1  receptor-type tyrosine-protein phosphatase delta isoform X20

  19. XM_017014963.2XP_016870452.1  receptor-type tyrosine-protein phosphatase delta isoform X2

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13751630
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:14011630
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  20. XM_017014959.2XP_016870448.1  receptor-type tyrosine-protein phosphatase delta isoform X1

  21. XM_017014971.2XP_016870460.1  receptor-type tyrosine-protein phosphatase delta isoform X12

  22. XM_024447625.1XP_024303393.1  receptor-type tyrosine-protein phosphatase delta isoform X11

    Conserved Domains (6) summary
    cd05739
    Location:243311
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:16561915
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:13951624
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9151006
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cd05738
    Location:143223
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
  23. XM_017014973.2XP_016870462.1  receptor-type tyrosine-protein phosphatase delta isoform X14

  24. XM_017014967.2XP_016870456.1  receptor-type tyrosine-protein phosphatase delta isoform X7

  25. XM_017014977.2XP_016870466.1  receptor-type tyrosine-protein phosphatase delta isoform X18

  26. XM_006716825.4XP_006716888.1  receptor-type tyrosine-protein phosphatase delta isoform X23

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13561611
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13821611
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  27. XM_017014968.2XP_016870457.1  receptor-type tyrosine-protein phosphatase delta isoform X8

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13711626
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13971626
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  28. XM_017014976.2XP_016870465.1  receptor-type tyrosine-protein phosphatase delta isoform X17

  29. XM_017014984.2XP_016870473.1  receptor-type tyrosine-protein phosphatase delta isoform X29

  30. XM_017014983.2XP_016870472.1  receptor-type tyrosine-protein phosphatase delta isoform X28

  31. XM_017014982.2XP_016870471.1  receptor-type tyrosine-protein phosphatase delta isoform X27

  32. XM_017014978.2XP_016870467.1  receptor-type tyrosine-protein phosphatase delta isoform X19

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13611616
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13871616
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  33. XM_017014975.2XP_016870464.1  receptor-type tyrosine-protein phosphatase delta isoform X16

  34. XM_017014995.2XP_016870484.1  receptor-type tyrosine-protein phosphatase delta isoform X44

  35. XM_006716827.4XP_006716890.1  receptor-type tyrosine-protein phosphatase delta isoform X25

    Conserved Domains (8) summary
    cd05738
    Location:143217
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:237305
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13371592
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132216
    IG_like; Immunoglobulin like
    cd00047
    Location:13631592
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:900991
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  36. XM_017014985.2XP_016870474.1  receptor-type tyrosine-protein phosphatase delta isoform X30

  37. XM_017014980.2XP_016870469.1  receptor-type tyrosine-protein phosphatase delta isoform X24

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13471602
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13731602
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9131004
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  38. XM_006716823.3XP_006716886.1  receptor-type tyrosine-protein phosphatase delta isoform X21

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13571612
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:13831612
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:9221013
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  39. XM_006716834.4XP_006716897.1  receptor-type tyrosine-protein phosphatase delta isoform X39

    Conserved Domains (8) summary
    cd05738
    Location:143217
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:237305
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9491204
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132216
    IG_like; Immunoglobulin like
    cd00047
    Location:9751204
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:310399
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  40. XM_017014988.2XP_016870477.1  receptor-type tyrosine-protein phosphatase delta isoform X33

  41. XM_017014987.2XP_016870476.1  receptor-type tyrosine-protein phosphatase delta isoform X32

  42. XM_017014986.2XP_016870475.1  receptor-type tyrosine-protein phosphatase delta isoform X31

  43. XM_017014990.2XP_016870479.1  receptor-type tyrosine-protein phosphatase delta isoform X35

  44. XM_017014989.2XP_016870478.1  receptor-type tyrosine-protein phosphatase delta isoform X34

  45. XM_017014992.2XP_016870481.1  receptor-type tyrosine-protein phosphatase delta isoform X40

  46. XM_024447627.1XP_024303395.1  receptor-type tyrosine-protein phosphatase delta isoform X46

    Conserved Domains (4) summary
    smart00194
    Location:9091168
    PTPc; Protein tyrosine phosphatase, catalytic domain
    cd00047
    Location:648877
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:169260
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cl21522
    Location:2159
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
  47. XM_017014981.2XP_016870470.1  receptor-type tyrosine-protein phosphatase delta isoform X26

    Conserved Domains (8) summary
    cd05738
    Location:143217
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:237305
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:13341589
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132216
    IG_like; Immunoglobulin like
    cd00047
    Location:13601589
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:900991
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  48. XM_017014994.2XP_016870483.1  receptor-type tyrosine-protein phosphatase delta isoform X43

    Conserved Domains (8) summary
    cd05738
    Location:143226
    Ig2_RPTP_IIa_LAR_like; Second immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    cd05739
    Location:250318
    Ig3_RPTP_IIa_LAR_like; Third immunoglobulin (Ig)-like domain of the receptor protein tyrosine phosphatase (RPTP)-F, also known as LAR
    smart00194
    Location:9451200
    PTPc; Protein tyrosine phosphatase, catalytic domain
    smart00410
    Location:132225
    IG_like; Immunoglobulin like
    cd00047
    Location:9711200
    PTPc; Protein tyrosine phosphatases (PTP) catalyze the dephosphorylation of phosphotyrosine peptides; they regulate phosphotyrosine levels in signal transduction pathways. The depth of the active site cleft renders the enzyme specific for phosphorylated Tyr ...
    cd00063
    Location:323412
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam07679
    Location:24115
    I-set; Immunoglobulin I-set domain
    cl11960
    Location:41115
    Ig; Immunoglobulin domain
  49. XM_017014993.2XP_016870482.1  receptor-type tyrosine-protein phosphatase delta isoform X41

  50. XM_017014962.2XP_016870451.1  receptor-type tyrosine-protein phosphatase delta isoform X1

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