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aceK isocitrate dehydrogenase kinase/phosphatase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 944797, updated on 10-Oct-2019

Summary

Gene symbol
aceK
Gene description
isocitrate dehydrogenase kinase/phosphatase
Primary source
EcoGene:EG10026
Locus tag
b4016
See related
ASAP:ABE-0013131; ECOCYC:EG10026
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK4008
Summary
Context determines which enzyme name is used, the kinase or the phosphatase. [More information is available at EcoCyc: EG10026].

Genomic context

Sequence:
NC_000913.3 (4218596..4220332)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene malate synthase A Neighboring gene isocitrate lyase Neighboring gene regulator of acetyl CoA synthetase Neighboring gene DNA-binding transcriptional repressor IclR Neighboring gene cobalamin-dependent methionine synthase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
AMP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
AMP binding IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
ATP binding IDA
Inferred from Direct Assay
more info
PubMed 
ATP binding IEA
Inferred from Electronic Annotation
more info
 
[isocitrate dehydrogenase (NADP+)] kinase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
[isocitrate dehydrogenase (NADP+)] kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
[isocitrate dehydrogenase (NADP+)] kinase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity, acting on ester bonds IEA
Inferred from Electronic Annotation
more info
 
kinase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
phosphoprotein phosphatase activity IEA
Inferred from Electronic Annotation
more info
 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
protein serine/threonine kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 
protein serine/threonine phosphatase activity IDA
Inferred from Direct Assay
more info
PubMed 
transferase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
glucose metabolic process IEA
Inferred from Electronic Annotation
more info
 
glyoxylate cycle IC
Inferred by Curator
more info
PubMed 
glyoxylate cycle IEA
Inferred from Electronic Annotation
more info
 
peptidyl-serine dephosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
peptidyl-serine phosphorylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
peptidyl-serine phosphorylation IDA
Inferred from Direct Assay
more info
PubMed 
phosphorylation IEA
Inferred from Electronic Annotation
more info
 
regulation of catalytic activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
regulation of catalytic activity IDA
Inferred from Direct Assay
more info
PubMed 
tricarboxylic acid cycle IC
Inferred by Curator
more info
PubMed 
tricarboxylic acid cycle IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytoplasm IC
Inferred by Curator
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 

General protein information

Preferred Names
isocitrate dehydrogenase kinase/phosphatase
NP_418440.1

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    4218596..4220332
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418440.1 isocitrate dehydrogenase kinase/phosphatase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418440.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P11071
    Conserved Domains (1) summary
    COG4579
    Location:1578
    AceK; Isocitrate dehydrogenase kinase/phosphatase [Signal transduction mechanisms]
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