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mnmE 5-carboxymethylaminomethyluridine-tRNA synthase GTPase subunit [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 948222, updated on 10-Oct-2019

Summary

Gene symbol
mnmE
Gene description
5-carboxymethylaminomethyluridine-tRNA synthase GTPase subunit
Primary source
EcoGene:EG10997
Locus tag
b3706
See related
ASAP:ABE-0012123; ECOCYC:EG10997
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK3699; thdF; trmE
Summary
GTPase activity is essential for modification function. [More information is available at EcoGene: EG10997]. MnmE is required for wild-type 5-methylaminomethyl-2-thiouridine modification of tRNA . [More information is available at EcoCyc: EG10997].

Genomic context

Sequence:
NC_000913.3 (3886828..3888192)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene RNase P protein component Neighboring gene membrane protein insertion efficiency factor Neighboring gene membrane protein insertase YidC Neighboring gene tnaAB operon leader peptide Neighboring gene tryptophanase

Bibliography

GeneRIFs: Gene References Into Functions

What's a GeneRIF?

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
GDP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IDA
Inferred from Direct Assay
more info
PubMed 
GTP binding IEA
Inferred from Electronic Annotation
more info
 
GTPase activity IDA
Inferred from Direct Assay
more info
PubMed 
GTPase activity IEA
Inferred from Electronic Annotation
more info
 
hydrolase activity IEA
Inferred from Electronic Annotation
more info
 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
metal ion binding IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
potassium ion binding IDA
Inferred from Direct Assay
more info
PubMed 
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
chaperone-mediated protein folding IDA
Inferred from Direct Assay
more info
PubMed 
response to pH IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA methylation IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tRNA methylation IMP
Inferred from Mutant Phenotype
more info
PubMed 
tRNA modification IEA
Inferred from Electronic Annotation
more info
 
tRNA processing IEA
Inferred from Electronic Annotation
more info
 
tRNA wobble uridine modification IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
tRNA wobble uridine modification IDA
Inferred from Direct Assay
more info
PubMed 
tRNA wobble uridine modification IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
cytoplasm IEA
Inferred from Electronic Annotation
more info
 
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 
plasma membrane IDA
Inferred from Direct Assay
more info
PubMed 

General protein information

Preferred Names
5-carboxymethylaminomethyluridine-tRNA synthase GTPase subunit

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    3886828..3888192
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_418162.1 5-carboxymethylaminomethyluridine-tRNA synthase GTPase subunit [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_418162.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P25522
    Conserved Domains (1) summary
    PRK05291
    Location:1454
    trmE; tRNA modification GTPase TrmE; Reviewed
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