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guaA GMP synthetase [ Escherichia coli str. K-12 substr. MG1655 ]

Gene ID: 947334, updated on 10-Oct-2019

Summary

Gene symbol
guaA
Gene description
GMP synthetase
Primary source
EcoGene:EG10420
Locus tag
b2507
See related
ASAP:ABE-0008254; ECOCYC:EG10420
Gene type
protein coding
RefSeq status
PROVISIONAL
Organism
Escherichia coli str. K-12 substr. MG1655 (strain: K-12, substrain: MG1655)
Lineage
Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales; Enterobacteriaceae; Escherichia
Also known as
ECK2503
Summary
GMP synthetase catalyzes the glutamine- or ammonia-dependent synthesis of GMP from XMP . [More information is available at EcoCyc: EG10420].

Genomic context

Sequence:
NC_000913.3 (2630958..2632535, complement)

NC_000913.3Genomic Context describing neighboring genes Neighboring gene lipoprotein YfgH Neighboring gene nalidixic acid resistance protein YfgI Neighboring gene inosine 5'-monophosphate dehydrogenase Neighboring gene exodeoxyribonuclease VII subunit XseA Neighboring gene zinc ribbon domain-containing protein YfgJ

Pathways from PubChem

Interactions

Products Interactant Other Gene Complex Source Pubs Description

General gene information

Gene Ontology Provided by GO

Function Evidence Code Pubs
ATP binding IEA
Inferred from Electronic Annotation
more info
 
GMP synthase (glutamine-hydrolyzing) activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GMP synthase (glutamine-hydrolyzing) activity IDA
Inferred from Direct Assay
more info
PubMed 
GMP synthase (glutamine-hydrolyzing) activity IEA
Inferred from Electronic Annotation
more info
 
GMP synthase activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GMP synthase activity IDA
Inferred from Direct Assay
more info
PubMed 
identical protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
ligase activity IEA
Inferred from Electronic Annotation
more info
 
nucleotide binding IEA
Inferred from Electronic Annotation
more info
 
pyrophosphatase activity IEA
Inferred from Electronic Annotation
more info
 
Process Evidence Code Pubs
GMP biosynthetic process IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
GMP biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
GMP biosynthetic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
glutamine metabolic process IEA
Inferred from Electronic Annotation
more info
 
purine nucleotide biosynthetic process IEA
Inferred from Electronic Annotation
more info
 
Component Evidence Code Pubs
cytosol IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
cytosol IDA
Inferred from Direct Assay
more info
PubMed 

NCBI Reference Sequences (RefSeq)

Genome Annotation

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference assembly

Genomic

  1. NC_000913.3 Reference assembly

    Range
    2630958..2632535 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. NP_417002.1 GMP synthetase [Escherichia coli str. K-12 substr. MG1655]

    See identical proteins and their annotated locations for NP_417002.1

    Status: PROVISIONAL

    UniProtKB/Swiss-Prot
    P04079
    Conserved Domains (1) summary
    PRK00074
    Location:5525
    guaA; GMP synthase; Reviewed
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