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Or4e2 olfactory receptor family 4 subfamily E member 5 [ Rattus norvegicus (Norway rat) ]

Gene ID: 364306, updated on 22-Sep-2022

Summary

Official Symbol
Or4e2provided by RGD
Official Full Name
olfactory receptor family 4 subfamily E member 5provided by RGD
Primary source
RGD:1334073
See related
Ensembl:ENSRNOG00000063163 AllianceGenome:RGD:1334073
Gene type
protein coding
RefSeq status
REVIEWED
Organism
Rattus norvegicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Rattus
Also known as
Olr1643
Summary
Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
Orthologs
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Genomic context

See Or4e2 in Genome Data Viewer
Location:
15p14
Exon count:
1
Annotation release Status Assembly Chr Location
108 current mRatBN7.2 (GCF_015227675.2) 15 NC_051350.1 (25187633..25188559)
106 previous assembly Rnor_6.0 (GCF_000001895.5) 15 NC_005114.4 (28894627..28895553)

Chromosome 15 - NC_051350.1Genomic Context describing neighboring genes Neighboring gene olfactory receptor family 10 subfamily G member 1 Neighboring gene ribosomal protein L7a, pseudogene 24 Neighboring gene PEST proteolytic signal containing nuclear protein, pseudogene 2 Neighboring gene olfactory receptor family 4 subfamily E member 2

Genomic regions, transcripts, and products

General gene information

Homology

Gene Ontology Provided by RGD

Function Evidence Code Pubs
enables G protein-coupled receptor activity IEA
Inferred from Electronic Annotation
more info
 
enables copper ion binding ISO
Inferred from Sequence Orthology
more info
 
enables odorant binding IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables odorant binding ISO
Inferred from Sequence Orthology
more info
 
enables olfactory receptor activity IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
enables olfactory receptor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables olfactory receptor activity ISO
Inferred from Sequence Orthology
more info
 
Component Evidence Code Pubs
is_active_in membrane IBA
Inferred from Biological aspect of Ancestor
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane ISO
Inferred from Sequence Orthology
more info
 
located_in plasma membrane ISO
Inferred from Sequence Orthology
more info
 

General protein information

Preferred Names
olfactory receptor Olr1643
Names
olfactory receptor 1643
olfactory receptor gene Olr1643

NCBI Reference Sequences (RefSeq)

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RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

mRNA and Protein(s)

  1. NM_001000535.1NP_001000535.1  olfactory receptor Olr1643

    See identical proteins and their annotated locations for NP_001000535.1

    Status: REVIEWED

    Source sequence(s)
    JACYVU010000263
    UniProtKB/TrEMBL
    D4ADC0
    Related
    ENSRNOP00000088210.1, ENSRNOT00000112245.1
    Conserved Domains (2) summary
    pfam00001
    Location:41287
    7tm_1; 7 transmembrane receptor (rhodopsin family)
    cl21561
    Location:31301
    7tm_4; Olfactory receptor

RefSeqs of Annotated Genomes: Rattus norvegicus Annotation Release 108 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mRatBN7.2 Primary Assembly

Genomic

  1. NC_051350.1 Reference mRatBN7.2 Primary Assembly

    Range
    25187633..25188559
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)