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    meru meru [ Drosophila melanogaster (fruit fly) ]

    Gene ID: 39727, updated on 7-Aug-2025
    Official Symbol
    meruprovided by FlyBase
    Official Full Name
    meruprovided by FlyBase
    Primary source
    FLYBASE:FBgn0052150
    Locus tag
    Dmel_CG32150
    See related
    AllianceGenome:FB:FBgn0052150
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Drosophila melanogaster
    Lineage
    Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota; Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea; Drosophilidae; Drosophila; Sophophora
    Also known as
    CG12712; CG15714; CG32150; Dmel\CG32150
    Summary
    Involved in asymmetric cell division. Located in apical plasma membrane and posterior cell cortex. Is expressed in wing disc. Orthologous to human RASSF10 (Ras association domain family member 10) and RASSF9 (Ras association domain family member 9). [provided by Alliance of Genome Resources, Jul 2025]
    Orthologs
    all
    Try the new Gene page
    Try the new Transcripts and proteins table
    See meru in Genome Data Viewer
    Location:
    72A2-72A2; 3-43 cM
    Exon count:
    5
    Annotation release Status Assembly Chr Location
    Release 6.54 current Release 6 plus ISO1 MT (GCF_000001215.4) 3L NT_037436.4 (15837773..15844062, complement)
    Release 5.57 previous assembly Release 5 (GCF_000001215.2) 3L NT_037436.3 (15830873..15837162, complement)

    Chromosome 3L - NT_037436.4Genomic Context describing neighboring genes Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein Neighboring gene mir-263b stem loop Neighboring gene pH-sensitive chloride channel 1 Neighboring gene long non-coding RNA:CR44051 Neighboring gene long non-coding RNA:CR44050

    Go to nucleotide: Graphics FASTA GenBank

    Related articles in PubMed

    1. Lateral inhibition: Two modes of non-autonomous negative autoregulation by neuralized. Miller SW, et al. PLoS Genet, 2018 Jul. PMID 30028887, Free PMC Article
    2. Drosophila microRNAs 263a/b confer robustness during development by protecting nascent sense organs from apoptosis. Hilgers V, et al. PLoS Biol, 2010 Jun 15. PMID 20563308, Free PMC Article
    3. Meru co-ordinates spindle orientation with cell polarity and cell cycle progression. McLellan MM, et al. EMBO J, 2025 May. PMID 40169811, Free PMC Article
    4. Meru couples planar cell polarity with apical-basal polarity during asymmetric cell division. Banerjee JJ, et al. Elife, 2017 Jun 30. PMID 28665270, Free PMC Article
    5. RASSF7 is a member of a new family of RAS association domain-containing proteins and is required for completing mitosis. Sherwood V, et al. Mol Biol Cell, 2008 Apr. PMID 18272789, Free PMC Article

    See all (34) citations in PubMed

    GeneRIFs: Gene References Into Functions

    Products Interactant Other Gene Complex Source Pubs Description

    Homology

    Gene Ontology Provided by FlyBase

    Process Evidence Code Pubs
    involved_in asymmetric cell division IMP
    Inferred from Mutant Phenotype
    more info
    		 PubMed 
    Component Evidence Code Pubs
    located_in apical plasma membrane IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in posterior cell cortex IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    Preferred Names
    meru
    Names
    CG32150-PA
    CG32150-PC
    CG32150-PD
    meru-PA
    meru-PC
    meru-PD

    NEW Try the new Transcript table

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NT_037436.4 Reference assembly

      Range
      15837773..15844062 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_168635.3 → NP_730077.1  meru, isoform A

      See identical proteins and their annotated locations for NP_730077.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUU9
      Related
      FBpp0075290

    2. NM_001259851.3 → NP_001246780.1  meru, isoform D

      See identical proteins and their annotated locations for NP_001246780.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      M9NDS6

    3. NM_001259850.3 → NP_001246779.1  meru, isoform C

      See identical proteins and their annotated locations for NP_001246779.1

      Status: REVIEWED

      UniProtKB/TrEMBL
      Q9VUU9
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    M9NDS6 M9NDS6
    Q9VUU9 Q9VUU9
    Q9VUV0 Q9VUV0

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