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    Cept1 choline/ethanolaminephosphotransferase 1 [ Mus musculus (house mouse) ]

    Gene ID: 99712, updated on 26-Sep-2022

    Summary

    Official Symbol
    Cept1provided by MGI
    Official Full Name
    choline/ethanolaminephosphotransferase 1provided by MGI
    Primary source
    MGI:MGI:2139793
    See related
    Ensembl:ENSMUSG00000040774 AllianceGenome:MGI:2139793
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mCEPT1; 9930118K05Rik
    Summary
    Enables phosphotransferase activity, for other substituted phosphate groups. Acts upstream of or within phosphatidylcholine biosynthetic process. Located in endoplasmic reticulum membrane. Is expressed in alimentary system; cranium; nervous system; nose; and urinary system. Orthologous to human CEPT1 (choline/ethanolamine phosphotransferase 1). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in bladder adult (RPKM 6.4), liver E18 (RPKM 5.4) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Cept1 in Genome Data Viewer
    Location:
    3; 3 F2.3
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (106409576..106455118, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (106502260..106547802, complement)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene chitinase-like 6 Neighboring gene RIKEN cDNA 2010016I18 gene Neighboring gene DENN/MADD domain containing 2D Neighboring gene DNA-damage regulated autophagy modulator 2 Neighboring gene ligand dependent nuclear receptor interacting factor 1 Neighboring gene CD53 antigen

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Targeted (1)  1 citation
    • Endonuclease-mediated (3) 

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables 1-alkenyl-2-acylglycerol choline phosphotransferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables diacylglycerol cholinephosphotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ethanolaminephosphotransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphotransferase activity, for other substituted phosphate groups IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in Golgi apparatus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in endoplasmic reticulum membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    choline/ethanolaminephosphotransferase 1
    Names
    1-alkenyl-2-acylglycerol choline phosphotransferase
    NP_001280623.1
    NP_001344747.1
    NP_001344748.1
    NP_598630.2
    XP_006502534.1
    XP_011238638.1
    XP_036019375.1

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001293694.1NP_001280623.1  choline/ethanolaminephosphotransferase 1 isoform 2

      See identical proteins and their annotated locations for NP_001280623.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon and contains an alternate exon but maintains the reading frame compared to variant 1. The encoded isoform (4) is the same length as isoform 1, but contains a distinct internal segment.
      Source sequence(s)
      AC117200, AC140380
      Consensus CDS
      CCDS79995.1
      UniProtKB/Swiss-Prot
      Q8BGS7
      UniProtKB/TrEMBL
      A0A8C6GWM7
      Related
      ENSMUSP00000037277.8, ENSMUST00000039153.14
      Conserved Domains (1) summary
      cl00453
      Location:43407
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    2. NM_001357818.1NP_001344747.1  choline/ethanolaminephosphotransferase 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117200, AC140380, CO425529, CX223901
      Consensus CDS
      CCDS17723.1
      UniProtKB/Swiss-Prot
      Q8VC64
      UniProtKB/TrEMBL
      A0A8C6GXP7
      Conserved Domains (1) summary
      cl00453
      Location:43407
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    3. NM_001357819.1NP_001344748.1  choline/ethanolaminephosphotransferase 1 isoform 1

      Status: VALIDATED

      Source sequence(s)
      AC117200, AC140380
      Consensus CDS
      CCDS17723.1
      UniProtKB/Swiss-Prot
      Q8VC64
      UniProtKB/TrEMBL
      A0A8C6GXP7
      Conserved Domains (1) summary
      cl00453
      Location:43407
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    4. NM_133869.4NP_598630.2  choline/ethanolaminephosphotransferase 1 isoform 1

      See identical proteins and their annotated locations for NP_598630.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) encodes isoform (1).
      Source sequence(s)
      AK037116, BY226430
      Consensus CDS
      CCDS17723.1
      UniProtKB/Swiss-Prot
      Q8BGS7, Q8VC64
      UniProtKB/TrEMBL
      A0A8C6GXP7
      Related
      ENSMUSP00000065743.5, ENSMUST00000068301.11
      Conserved Domains (1) summary
      cl00453
      Location:43407
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      106409576..106455118 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006502471.5XP_006502534.1  choline/ethanolaminephosphotransferase 1 isoform X1

      See identical proteins and their annotated locations for XP_006502534.1

      UniProtKB/Swiss-Prot
      Q8BGS7, Q8VC64
      UniProtKB/TrEMBL
      A0A8C6GXP7
      Related
      ENSMUSP00000112509.2, ENSMUST00000121231.8
      Conserved Domains (1) summary
      cl00453
      Location:43407
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    2. XM_011240336.3XP_011238638.1  choline/ethanolaminephosphotransferase 1 isoform X2

      Conserved Domains (1) summary
      cl00453
      Location:43209
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase
    3. XM_036163482.1XP_036019375.1  choline/ethanolaminephosphotransferase 1 isoform X2

      Conserved Domains (1) summary
      cl00453
      Location:43209
      CDP-OH_P_transf; CDP-alcohol phosphatidyltransferase

    RNA

    1. XR_375610.4 RNA Sequence

    2. XR_001783787.3 RNA Sequence

    3. XR_003954431.2 RNA Sequence

    4. XR_001783786.3 RNA Sequence