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    Ubac1 ubiquitin associated domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 98766, updated on 23-Jun-2021

    Summary

    Official Symbol
    Ubac1provided by MGI
    Official Full Name
    ubiquitin associated domain containing 1provided by MGI
    Primary source
    MGI:MGI:1920995
    See related
    Ensembl:ENSMUSG00000036352
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Kpc; Kpc2; GBDR1; Gdbr1; Ubadc; Ubadc1; AA407978; 1110033G07Rik
    Expression
    Broad expression in liver E14.5 (RPKM 72.0), liver E14 (RPKM 70.3) and 27 other tissues See more
    Orthologs
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    Genomic context

    See Ubac1 in Genome Data Viewer
    Location:
    2; 2 A3
    Exon count:
    12
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (25886970..25911793, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (25996958..26021781, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (25852478..25877280, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene potassium channel, subfamily T, member 1 Neighboring gene calmodulin regulated spectrin-associated protein 1 Neighboring gene nucleus accumbens associated 2, BEN and BTB (POZ) domain containing Neighboring gene predicted gene, 54107

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (1) 
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    ubiquitin-associated domain-containing protein 1
    Names
    E3 ubiquitin-protein ligase subunit KPC2
    UBA domain-containing protein 1
    kip1 ubiquitination-promoting complex protein 2
    putative glialblastoma cell differentiation-related

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001362681.1NP_001349610.1  ubiquitin-associated domain-containing protein 1 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate exon in the 3' end compared to variant 1, that causes a frameshift. The resulting isoform (2) has a shorter and distinct C-terminus compared to isoform 1.
      Source sequence(s)
      AL731682, AL845455
      Conserved Domains (2) summary
      cd14303
      Location:195232
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cl21463
      Location:294325
      UBA_like_SF; UBA domain-like superfamily
    2. NM_133835.2NP_598596.2  ubiquitin-associated domain-containing protein 1 isoform 1

      See identical proteins and their annotated locations for NP_598596.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AK157857, AK162577, CX243095
      Consensus CDS
      CCDS15795.1
      UniProtKB/Swiss-Prot
      Q8VDI7
      Related
      ENSMUSP00000040220.8, ENSMUST00000036509.14
      Conserved Domains (3) summary
      smart00727
      Location:357396
      STI1; Heat shock chaperonin-binding motif
      cd14303
      Location:195232
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cd14304
      Location:294331
      UBA2_KPC2; UBA2 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      25886970..25911793 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006498465.1XP_006498528.1  ubiquitin-associated domain-containing protein 1 isoform X1

      Conserved Domains (2) summary
      cd14303
      Location:195232
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cd17066
      Location:995
      Ubl_KPC2; ubiquitin-like (Ubl) domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
    2. XM_036162737.1XP_036018630.1  ubiquitin-associated domain-containing protein 1 isoform X4

      Conserved Domains (2) summary
      cd14303
      Location:93130
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cl21463
      Location:192223
      UBA_like_SF; UBA domain-like superfamily
    3. XM_030252261.2XP_030108121.1  ubiquitin-associated domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      smart00727
      Location:213252
      STI1; Heat shock chaperonin-binding motif
      cd14303
      Location:5188
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cd14304
      Location:150187
      UBA2_KPC2; UBA2 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
    4. XM_036162736.1XP_036018629.1  ubiquitin-associated domain-containing protein 1 isoform X2

      Conserved Domains (3) summary
      smart00727
      Location:255294
      STI1; Heat shock chaperonin-binding motif
      cd14303
      Location:93130
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cd14304
      Location:192229
      UBA2_KPC2; UBA2 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
    5. XM_030252260.2XP_030108120.1  ubiquitin-associated domain-containing protein 1 isoform X2

      Conserved Domains (3) summary
      smart00727
      Location:255294
      STI1; Heat shock chaperonin-binding motif
      cd14303
      Location:93130
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cd14304
      Location:192229
      UBA2_KPC2; UBA2 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
    6. XM_030252262.2XP_030108122.1  ubiquitin-associated domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      smart00727
      Location:213252
      STI1; Heat shock chaperonin-binding motif
      cd14303
      Location:5188
      UBA1_KPC2; UBA1 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins
      cd14304
      Location:150187
      UBA2_KPC2; UBA2 domain found in Kip1 ubiquitination-promoting complex protein 2 (KPC2) and similar proteins

    RNA

    1. XR_004940785.1 RNA Sequence

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