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    Lrrc59 leucine rich repeat containing 59 [ Mus musculus (house mouse) ]

    Gene ID: 98238, updated on 26-Sep-2022

    Summary

    Official Symbol
    Lrrc59provided by MGI
    Official Full Name
    leucine rich repeat containing 59provided by MGI
    Primary source
    MGI:MGI:2138133
    See related
    Ensembl:ENSMUSG00000020869 AllianceGenome:MGI:2138133
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to be located in endoplasmic reticulum and mitochondrial nucleoid. Is expressed in several structures, including central nervous system and neural retina. Orthologous to human LRRC59 (leucine rich repeat containing 59). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in large intestine adult (RPKM 85.9), placenta adult (RPKM 76.8) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Lrrc59 in Genome Data Viewer
    Location:
    11; 11 D
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 11 NC_000077.7 (94520603..94536049)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 11 NC_000077.6 (94629777..94645223)

    Chromosome 11 - NC_000077.7Genomic Context describing neighboring genes Neighboring gene radical S-adenosyl methionine domain containing 1 Neighboring gene acyl-CoA synthetase family member 2 Neighboring gene chondroadherin Neighboring gene essential meiotic structure-specific endonuclease 1 Neighboring gene mitochondrial ribosomal protein L27 Neighboring gene xylosyltransferase II

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Gene trapped (1) 
    • Endonuclease-mediated (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    located_in intracellular membrane-bounded organelle IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in mitochondrial nucleoid ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    leucine-rich repeat-containing protein 59

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_133807.2NP_598568.1  leucine-rich repeat-containing protein 59

      See identical proteins and their annotated locations for NP_598568.1

      Status: VALIDATED

      Source sequence(s)
      AK159552, CX203638
      Consensus CDS
      CCDS25261.1
      UniProtKB/Swiss-Prot
      Q3TX86, Q922Q8
      Related
      ENSMUSP00000021239.7, ENSMUST00000021239.7
      Conserved Domains (3) summary
      PTZ00121
      Location:146228
      PTZ00121; MAEBL; Provisional
      COG4886
      Location:18120
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      sd00031
      Location:1940
      LRR_1; leucine-rich repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000077.7 Reference GRCm39 C57BL/6J

      Range
      94520603..94536049
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)