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    Deptor DEP domain containing MTOR-interacting protein [ Mus musculus (house mouse) ]

    Gene ID: 97998, updated on 8-Jul-2021

    Summary

    Official Symbol
    Deptorprovided by MGI
    Official Full Name
    DEP domain containing MTOR-interacting proteinprovided by MGI
    Primary source
    MGI:MGI:2146322
    See related
    Ensembl:ENSMUSG00000022419
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Depdc; Depdc6; D15Ertd336; D15Ertd597
    Expression
    Broad expression in bladder adult (RPKM 11.6), subcutaneous fat pad adult (RPKM 8.1) and 23 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Deptor in Genome Data Viewer
    Location:
    15 D1; 15 21.96 cM
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 15 NC_000081.7 (54975713..55122669)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 15 NC_000081.6 (55112317..55259273)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 15 NC_000081.5 (54944038..55085757)

    Chromosome 15 - NC_000081.7Genomic Context describing neighboring genes Neighboring gene TATA-box binding protein associated factor 2 Neighboring gene DNA replication and sister chromatid cohesion 1 Neighboring gene predicted gene, 41325 Neighboring gene predicted gene 9920 Neighboring gene predicted gene, 26296 Neighboring gene predicted gene, 35312

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA4200

    General protein information

    Preferred Names
    DEP domain-containing mTOR-interacting protein
    Names
    DEP domain-containing protein 6

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001037937.3NP_001033026.1  DEP domain-containing mTOR-interacting protein isoform b

      See identical proteins and their annotated locations for NP_001033026.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate 5'-terminal exon and initiates translation at an alternate start codon, compared to variant 1. The encoded isoform (b) is shorter, compared to isoform a.
      Source sequence(s)
      AC124659, AK139888, AK220300
      Consensus CDS
      CCDS27475.1
      UniProtKB/Swiss-Prot
      Q570Y9
      UniProtKB/TrEMBL
      B2ZRS7
      Related
      ENSMUSP00000023056.8, ENSMUST00000023056.8
      Conserved Domains (3) summary
      cd00992
      Location:327391
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04441
      Location:121205
      DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
      cl02442
      Location:29105
      DEP; DEP domain, named after Dishevelled, Egl-10, and Pleckstrin, where this domain was first discovered. The function of this domain is still not clear, but it is believed to be important for the membrane association of the signaling proteins in which it is ...
    2. NM_145470.3NP_663445.2  DEP domain-containing mTOR-interacting protein isoform a

      See identical proteins and their annotated locations for NP_663445.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (a).
      Source sequence(s)
      AC124659, AK220300, DV649395
      Consensus CDS
      CCDS27474.1
      UniProtKB/Swiss-Prot
      Q570Y9
      UniProtKB/TrEMBL
      B2ZRS3
      Related
      ENSMUSP00000094167.4, ENSMUST00000096433.10
      Conserved Domains (3) summary
      cd00992
      Location:339403
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      cd04441
      Location:133217
      DEP_2_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 2 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.
      cd04442
      Location:36117
      DEP_1_DEP6; DEP (Dishevelled, Egl-10, and Pleckstrin) domain 1 found in DEP6-like proteins. DEP6 proteins contain two DEP and a PDZ domain. Their function is unknown.

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000081.7 Reference GRCm39 C57BL/6J

      Range
      54975713..55122669
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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