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    Strn4 striatin, calmodulin binding protein 4 [ Mus musculus (house mouse) ]

    Gene ID: 97387, updated on 23-Jun-2021

    Summary

    Official Symbol
    Strn4provided by MGI
    Official Full Name
    striatin, calmodulin binding protein 4provided by MGI
    Primary source
    MGI:MGI:2142346
    See related
    Ensembl:ENSMUSG00000030374
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Z; ZIN; C80611; zinedin
    Expression
    Ubiquitous expression in whole brain E14.5 (RPKM 50.8), CNS E18 (RPKM 43.7) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Strn4 in Genome Data Viewer
    Location:
    7; 7 A2
    Exon count:
    19
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (16549814..16574856)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (16815889..16840931)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (17401238..17426280)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene adaptor-related protein complex 2, sigma 1 subunit Neighboring gene solute carrier family 1 (neutral amino acid transporter), member 5 Neighboring gene fukutin related protein Neighboring gene protein kinase D2 Neighboring gene RIKEN cDNA 9330104G04 gene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (3) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables armadillo repeat domain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables armadillo repeat domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein domain specific binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein phosphatase 2A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein phosphatase 2A binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    Component Evidence Code Pubs
    part_of FAR/SIN/STRIPAK complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell junction IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cell projection IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in dendritic spine ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in synapse IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039878.2NP_001034967.1  striatin-4 isoform 2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) uses an alternate splice site in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal 7-aa segment, compared to isoform 1.
      Source sequence(s)
      AC148981, AK136155, BC066805
      Consensus CDS
      CCDS39787.1
      UniProtKB/Swiss-Prot
      P58404
      Related
      ENSMUSP00000104135.2, ENSMUST00000108495.9
      Conserved Domains (4) summary
      COG2319
      Location:416746
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:430752
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:64189
      Striatin; Striatin family
      sd00039
      Location:443489
      7WD40; WD40 repeat [structural motif]
    2. NM_133789.3NP_598550.2  striatin-4 isoform 1

      See identical proteins and their annotated locations for NP_598550.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AC148981, BC066805, BC080283
      Consensus CDS
      CCDS39786.1
      UniProtKB/Swiss-Prot
      P58404
      Related
      ENSMUSP00000019220.9, ENSMUST00000019220.16
      Conserved Domains (4) summary
      COG2319
      Location:423753
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:437759
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:64189
      Striatin; Striatin family
      sd00039
      Location:450496
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      16549814..16574856
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017312409.2XP_017167898.1  striatin-4 isoform X3

      Conserved Domains (1) summary
      pfam08232
      Location:64189
      Striatin; Striatin family
    2. XM_036153606.1XP_036009499.1  striatin-4 isoform X4

      Conserved Domains (1) summary
      pfam08232
      Location:65189
      Striatin; Striatin family
    3. XM_006540446.3XP_006540509.1  striatin-4 isoform X1

      Conserved Domains (3) summary
      cd00200
      Location:318640
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:331377
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:170
      Striatin; Striatin family
    4. XM_017312408.2XP_017167897.1  striatin-4 isoform X2

      Conserved Domains (3) summary
      cd00200
      Location:311633
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:324370
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:170
      Striatin; Striatin family
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