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    Nmd3 NMD3 ribosome export adaptor [ Mus musculus (house mouse) ]

    Gene ID: 97112, updated on 25-Aug-2022

    Summary

    Official Symbol
    Nmd3provided by MGI
    Official Full Name
    NMD3 ribosome export adaptorprovided by MGI
    Primary source
    MGI:MGI:2140103
    See related
    Ensembl:ENSMUSG00000027787 AllianceGenome:MGI:2140103
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Summary
    Predicted to enable protein-macromolecule adaptor activity and ribosomal large subunit binding activity. Predicted to be involved in several processes, including positive regulation of protein binding activity; positive regulation of protein localization to nucleolus; and ribosomal large subunit export from nucleus. Predicted to act upstream of or within protein transport. Predicted to be located in nucleolus and nucleoplasm. Predicted to be active in cytoplasm and nucleus. Orthologous to human NMD3 (NMD3 ribosome export adaptor). [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Ubiquitous expression in placenta adult (RPKM 13.4), CNS E11.5 (RPKM 10.0) and 28 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See Nmd3 in Genome Data Viewer
    Location:
    3; 3 E1- E2
    Exon count:
    16
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (69629301..69656380)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (69722055..69749047)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (69525977..69552969)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA48 Neighboring gene ribosomal protein L32, pseudogene Neighboring gene predicted gene, 52662 Neighboring gene ribosome production factor 2 homolog pseudogene Neighboring gene serine palmitoyltransferase, small subunit B Neighboring gene predicted gene, 52608

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein-macromolecule adaptor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ribosomal large subunit binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables ribosomal large subunit binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in cytoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleolus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    60S ribosomal export protein NMD3
    Names
    NMD3 homolog

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001411212.1NP_001398141.1  60S ribosomal export protein NMD3 isoform 2

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    2. NM_001411213.1NP_001398142.1  60S ribosomal export protein NMD3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    3. NM_001411214.1NP_001398143.1  60S ribosomal export protein NMD3 isoform 4

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    4. NM_001411215.1NP_001398144.1  60S ribosomal export protein NMD3 isoform 5

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    5. NM_001411216.1NP_001398145.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    6. NM_001411217.1NP_001398146.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    7. NM_001411218.1NP_001398147.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    8. NM_001411219.1NP_001398148.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    9. NM_001411220.1NP_001398149.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    10. NM_001411221.1NP_001398150.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    11. NM_001411222.1NP_001398151.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    12. NM_001411223.1NP_001398152.1  60S ribosomal export protein NMD3 isoform 6

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    13. NM_001411224.1NP_001398153.1  60S ribosomal export protein NMD3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    14. NM_001411225.1NP_001398154.1  60S ribosomal export protein NMD3 isoform 7

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
    15. NM_133787.3NP_598548.1  60S ribosomal export protein NMD3 isoform 1

      See identical proteins and their annotated locations for NP_598548.1

      Status: VALIDATED

      Source sequence(s)
      AC115035, AC162790
      Consensus CDS
      CCDS17407.1
      UniProtKB/Swiss-Prot
      Q8BM61, Q99L48
      Related
      ENSMUSP00000029358.9, ENSMUST00000029358.15
      Conserved Domains (1) summary
      pfam04981
      Location:17246
      NMD3; NMD3 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      69629301..69656380
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163432.1XP_036019325.1  60S ribosomal export protein NMD3 isoform X1

      Conserved Domains (1) summary
      pfam04981
      Location:1126
      NMD3; NMD3 family
    2. XM_036163433.1XP_036019326.1  60S ribosomal export protein NMD3 isoform X1

      Conserved Domains (1) summary
      pfam04981
      Location:1126
      NMD3; NMD3 family