Format

Send to:

Choose Destination
    • Showing Current items.

    NCOR1 nuclear receptor corepressor 1 [ Homo sapiens (human) ]

    Gene ID: 9611, updated on 5-Jan-2022

    Summary

    Official Symbol
    NCOR1provided by HGNC
    Official Full Name
    nuclear receptor corepressor 1provided by HGNC
    Primary source
    HGNC:HGNC:7672
    See related
    Ensembl:ENSG00000141027 MIM:600849
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    N-CoR; TRAC1; N-CoR1; hN-CoR; PPP1R109
    Summary
    This gene encodes a protein that mediates ligand-independent transcription repression of thyroid-hormone and retinoic-acid receptors by promoting chromatin condensation and preventing access of the transcription machinery. It is part of a complex which also includes histone deacetylases and transcriptional regulators similar to the yeast protein Sin3p. This gene is located between the Charcot-Marie-Tooth and Smith-Magenis syndrome critical regions on chromosome 17. Alternate splicing results in multiple transcript variants. Pseudogenes of this gene are found on chromosomes 17 and 20.[provided by RefSeq, Jun 2010]
    Expression
    Ubiquitous expression in thyroid (RPKM 10.9), colon (RPKM 10.7) and 25 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See NCOR1 in Genome Data Viewer
    Location:
    17p12-p11.2
    Exon count:
    54
    Annotation release Status Assembly Chr Location
    109.20211119 current GRCh38.p13 (GCF_000001405.39) 17 NC_000017.11 (16029157..16216475, complement)
    105.20201022 previous assembly GRCh37.p13 (GCF_000001405.25) 17 NC_000017.10 (15932471..16118848, complement)

    Chromosome 17 - NC_000017.11Genomic Context describing neighboring genes Neighboring gene adenosine A2b receptor Neighboring gene zinc finger SWIM-type containing 7 Neighboring gene tetratricopeptide repeat domain 19 Neighboring gene Sharpr-MPRA regulatory region 10193 Neighboring gene ribosomal protein lateral stalk subunit P1 pseudogene 11 Neighboring gene ribosomal protein L22 pseudogene 21 Neighboring gene RNA, U6 small nuclear 314, pseudogene Neighboring gene RNA, U6 small nuclear 862, pseudogene Neighboring gene small nucleolar RNA, C/D box 163 Neighboring gene RNA, 7SL, cytoplasmic 442, pseudogene Neighboring gene phosphatidylinositol glycan anchor biosynthesis class L Neighboring gene Sharpr-MPRA regulatory region 12459 Neighboring gene microRNA 1288

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    HIV-1 interactions

    Protein interactions

    Protein Gene Interaction Pubs
    Vif vif HIV-1 Vif is identified to have a physical interaction with nuclear receptor corepressor 1 (NCOR1) in human HEK293 and/or Jurkat cell lines by using affinity tagging and purification mass spectrometry analyses PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • KIAA1047, MGC104216

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables RNA polymerase II-specific DNA-binding transcription factor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables histone deacetylase binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables nuclear receptor binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables thyroid hormone receptor binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription cis-regulatory region binding ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    enables transcription corepressor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables transcription corepressor activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    enables transcription corepressor activity IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in chromatin organization IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in locomotor rhythm ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in negative regulation of JNK cascade IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in negative regulation of androgen receptor signaling pathway IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of fatty acid metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of glycolytic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of production of miRNAs involved in gene silencing by miRNA IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in negative regulation of transcription by RNA polymerase II IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of transcription, DNA-templated IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of transcription, DNA-templated ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    involved_in regulation of transcription by RNA polymerase II IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in spindle assembly IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in chromatin IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
     
    part_of histone deacetylase complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane HDA PubMed 
    located_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleoplasm IDA
    Inferred from Direct Assay
    more info
     
    located_in nucleoplasm TAS
    Traceable Author Statement
    more info
     
    located_in nucleus IC
    Inferred by Curator
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    part_of transcription repressor complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    nuclear receptor corepressor 1
    Names
    protein phosphatase 1, regulatory subunit 109
    thyroid hormone- and retinoic acid receptor-associated corepressor 1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_047111.1 RefSeqGene

      Range
      6213..192590
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001190438.1NP_001177367.1  nuclear receptor corepressor 1 isoform 2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (2) has multiple differences compared to variant 1, one of which results in a translational frameshift. The resulting protein (isoform 2) has a distinct C-terminus and is shorter than isoform 1.
      Source sequence(s)
      AF303586, BC056862
      Consensus CDS
      CCDS54094.1
      UniProtKB/Swiss-Prot
      O75376
      UniProtKB/TrEMBL
      Q6PGR4
      Related
      ENSP00000379189.1, ENST00000395848.5
      Conserved Domains (4) summary
      pfam05887
      Location:596677
      Trypan_PARP; Procyclic acidic repetitive protein (PARP)
      smart00717
      Location:518563
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:518561
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:41128
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    2. NM_001190440.1NP_001177369.1  nuclear receptor corepressor 1 isoform 3

      See identical proteins and their annotated locations for NP_001177369.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is shorter than isoform 1.
      Source sequence(s)
      AB028970, AC002553, AW015698, BC056862
      Consensus CDS
      CCDS54095.1
      UniProtKB/Swiss-Prot
      O75376
      UniProtKB/TrEMBL
      Q6PGR4
      Related
      ENSP00000379192.1, ENST00000395851.5
      Conserved Domains (4) summary
      cd00167
      Location:440482
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:627670
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:723919
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    3. NM_006311.4NP_006302.2  nuclear receptor corepressor 1 isoform 1

      See identical proteins and their annotated locations for NP_006302.2

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC002553, AF044209, AW015698, BJ995810
      Consensus CDS
      CCDS11175.1
      UniProtKB/Swiss-Prot
      O75376
      UniProtKB/TrEMBL
      A0A024RD47
      Related
      ENSP00000268712.2, ENST00000268712.8
      Conserved Domains (4) summary
      cd00167
      Location:440482
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:627670
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:704914
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB

    RefSeqs of Annotated Genomes: Homo sapiens Updated Annotation Release 109.20211119

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p13 Primary Assembly

    Genomic

    1. NC_000017.11 Reference GRCh38.p13 Primary Assembly

      Range
      16029157..16216475 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011524086.3XP_011522388.1  nuclear receptor corepressor 1 isoform X16

      See identical proteins and their annotated locations for XP_011522388.1

      UniProtKB/Swiss-Prot
      O75376
      Conserved Domains (4) summary
      cd00167
      Location:440482
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:627670
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:723919
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    2. XM_017025415.2XP_016880904.1  nuclear receptor corepressor 1 isoform X9

    3. XM_017025418.2XP_016880907.1  nuclear receptor corepressor 1 isoform X14

    4. XM_011524084.3XP_011522386.1  nuclear receptor corepressor 1 isoform X3

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:688770
      SDA1; SDA1
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    5. XM_006721603.4XP_006721666.1  nuclear receptor corepressor 1 isoform X6

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:688770
      SDA1; SDA1
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    6. XM_017025406.2XP_016880895.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    7. XM_011524083.3XP_011522385.1  nuclear receptor corepressor 1 isoform X1

      See identical proteins and their annotated locations for XP_011522385.1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    8. XM_017025411.2XP_016880900.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    9. XM_017025397.2XP_016880886.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    10. XM_017025401.2XP_016880890.1  nuclear receptor corepressor 1 isoform X2

      Conserved Domains (3) summary
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:692866
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    11. XM_017025400.2XP_016880889.1  nuclear receptor corepressor 1 isoform X2

      Conserved Domains (3) summary
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:692866
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    12. XM_017025396.2XP_016880885.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    13. XM_006721601.4XP_006721664.1  nuclear receptor corepressor 1 isoform X1

      See identical proteins and their annotated locations for XP_006721664.1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    14. XM_017025416.2XP_016880905.1  nuclear receptor corepressor 1 isoform X10

      Conserved Domains (4) summary
      cd00167
      Location:440482
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:627670
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:723919
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    15. XM_017025409.2XP_016880898.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    16. XM_006721602.4XP_006721665.1  nuclear receptor corepressor 1 isoform X2

      See identical proteins and their annotated locations for XP_006721665.1

      Conserved Domains (3) summary
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:692866
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    17. XM_017025403.2XP_016880892.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    18. XM_006721604.4XP_006721667.1  nuclear receptor corepressor 1 isoform X10

      Conserved Domains (4) summary
      cd00167
      Location:440482
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:627670
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:723919
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    19. XM_005256872.5XP_005256929.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    20. XM_005256871.5XP_005256928.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    21. XM_005256866.5XP_005256923.1  nuclear receptor corepressor 1 isoform X1

      See identical proteins and their annotated locations for XP_005256923.1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    22. XM_005256868.5XP_005256925.1  nuclear receptor corepressor 1 isoform X2

      See identical proteins and their annotated locations for XP_005256925.1

      Conserved Domains (3) summary
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:692866
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    23. XM_017025420.2XP_016880909.1  nuclear receptor corepressor 1 isoform X17

    24. XM_017025417.2XP_016880906.1  nuclear receptor corepressor 1 isoform X11

    25. XM_005256873.5XP_005256930.1  nuclear receptor corepressor 1 isoform X7

      Conserved Domains (3) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    26. XM_017025419.2XP_016880908.1  nuclear receptor corepressor 1 isoform X15

    27. XM_005256874.5XP_005256931.1  nuclear receptor corepressor 1 isoform X8

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:688770
      SDA1; SDA1
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    28. XM_005256875.4XP_005256932.1  nuclear receptor corepressor 1 isoform X12

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:688770
      SDA1; SDA1
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    29. XM_011524085.3XP_011522387.1  nuclear receptor corepressor 1 isoform X13

      Conserved Domains (4) summary
      smart00717
      Location:637682
      SANT; SANT SWI3, ADA2, N-CoR and TFIIIB'' DNA-binding domains
      cd00167
      Location:637680
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam05285
      Location:688770
      SDA1; SDA1
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
    30. XM_017025410.2XP_016880899.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    31. XM_017025404.2XP_016880893.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    32. XM_024451041.1XP_024306809.1  nuclear receptor corepressor 1 isoform X2

      Conserved Domains (3) summary
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:692866
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    33. XM_017025398.2XP_016880887.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    34. XM_024451043.1XP_024306811.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    35. XM_017025407.2XP_016880896.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    36. XM_017025414.2XP_016880903.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    37. XM_017025412.2XP_016880901.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    38. XM_017025405.2XP_016880894.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    39. XM_017025399.2XP_016880888.1  nuclear receptor corepressor 1 isoform X1

      Conserved Domains (4) summary
      cd00167
      Location:449491
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam00249
      Location:637680
      Myb_DNA-binding; Myb-like DNA-binding domain
      pfam15784
      Location:149238
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      NF033845
      Location:733929
      MSCRAMM_ClfB; MSCRAMM family adhesin clumping factor ClfB
    40. XM_017025408.2XP_016880897.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    41. XM_017025413.2XP_016880902.1  nuclear receptor corepressor 1 isoform X5

      Conserved Domains (3) summary
      cd00167
      Location:627670
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:683857
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    42. XM_024451042.1XP_024306810.1  nuclear receptor corepressor 1 isoform X4

      Conserved Domains (3) summary
      cd00167
      Location:628671
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:684858
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    43. XM_017025402.2XP_016880891.1  nuclear receptor corepressor 1 isoform X2

      Conserved Domains (3) summary
      cd00167
      Location:636679
      SANT; 'SWI3, ADA2, N-CoR and TFIIIB' DNA-binding domains. Tandem copies of the domain bind telomeric DNA tandem repeatsas part of the capping complex. Binding is sequence dependent for repeats which contain the G/C rich motif [C2-3 A (CA)1-6]. The domain is ...
      pfam15784
      Location:150237
      GPS2_interact; G-protein pathway suppressor 2-interacting domain
      cl26247
      Location:692866
      DNA_pol3_delta2; DNA polymerase III, delta subunit
    Support Center