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    Cnnm4 cyclin M4 [ Mus musculus (house mouse) ]

    Gene ID: 94220, updated on 23-Jun-2021

    Summary

    Official Symbol
    Cnnm4provided by MGI
    Official Full Name
    cyclin M4provided by MGI
    Primary source
    MGI:MGI:2151060
    See related
    Ensembl:ENSMUSG00000037408
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Acd; Acdp4; 5430430O18Rik
    Expression
    Biased expression in colon adult (RPKM 97.1), large intestine adult (RPKM 49.6) and 6 other tissues See more
    Orthologs
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    Genomic context

    See Cnnm4 in Genome Data Viewer
    Location:
    1 B; 1 15.28 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 1 NC_000067.7 (36510678..36547857)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 1 NC_000067.6 (36471597..36508776)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 1 NC_000067.5 (36528442..36565621)

    Chromosome 1 - NC_000067.7Genomic Context describing neighboring genes Neighboring gene fer-1-like 5 (C. elegans) Neighboring gene lectin, mannose-binding 2-like Neighboring gene predicted gene, 33401 Neighboring gene predicted gene, 33454 Neighboring gene cyclin M3 Neighboring gene ankyrin repeat domain 23 Neighboring gene ankyrin repeat domain 39

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Process Evidence Code Pubs
    acts_upstream_of_or_within biomineral tissue development IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within enamel mineralization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    acts_upstream_of_or_within ion transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in magnesium ion homeostasis IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within magnesium ion homeostasis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in magnesium ion transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within magnesium ion transport IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in metal ion homeostasis ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within response to stimulus IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in transport IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within visual perception IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in basolateral plasma membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    is_active_in intracellular membrane-bounded organelle IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    metal transporter CNNM4
    Names
    ancient conserved domain protein 4
    ancient conserved domain-containing protein 4
    mACDP4

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_033570.2NP_291048.2  metal transporter CNNM4 precursor

      See identical proteins and their annotated locations for NP_291048.2

      Status: VALIDATED

      Source sequence(s)
      AK164200, AK173209, CJ168962
      Consensus CDS
      CCDS14879.2
      UniProtKB/Swiss-Prot
      Q69ZF7
      Related
      ENSMUSP00000121317.2, ENSMUST00000153128.2
      Conserved Domains (3) summary
      COG0517
      Location:370497
      CBS; CBS domain [Signal transduction mechanisms]
      cd04590
      Location:379499
      CBS_pair_CorC_HlyC_assoc; This cd contains two tandem repeats of the cystathionine beta-synthase (CBS pair) domains associated with the CorC_HlyC domain. CorC_HlyC is a transporter associated domain. This small domain is found in Na+/H+ antiporters, in proteins involved in ...
      pfam01595
      Location:193355
      DUF21; Domain of unknown function DUF21

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000067.7 Reference GRCm39 C57BL/6J

      Range
      36510678..36547857
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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