Format

Send to:

Choose Destination
    • Showing Current items.

    Strn3 striatin, calmodulin binding protein 3 [ Mus musculus (house mouse) ]

    Gene ID: 94186, updated on 26-Jul-2021

    Summary

    Official Symbol
    Strn3provided by MGI
    Official Full Name
    striatin, calmodulin binding protein 3provided by MGI
    Primary source
    MGI:MGI:2151064
    See related
    Ensembl:ENSMUSG00000020954
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    SG; Gs2na; SG2NA
    Expression
    Ubiquitous expression in CNS E11.5 (RPKM 20.8), bladder adult (RPKM 19.5) and 28 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See Strn3 in Genome Data Viewer
    Location:
    12; 12 B3
    Exon count:
    20
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 12 NC_000078.7 (51655324..51743942, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 12 NC_000078.6 (51608541..51692351, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 12 NC_000078.5 (52709528..52792901, complement)

    Chromosome 12 - NC_000078.7Genomic Context describing neighboring genes Neighboring gene zyg-11 homolog A pseudogene Neighboring gene cochlin Neighboring gene adaptor-related protein complex AP-4, sigma 1 Neighboring gene predicted gene, 22663 Neighboring gene HECT domain E3 ubiquitin protein ligase 1 Neighboring gene predicted gene 5785

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Targeted (2) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables armadillo repeat domain binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables armadillo repeat domain binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables calmodulin binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein phosphatase 2A binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein phosphatase 2A binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein-containing complex binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables protein-containing complex binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables small GTPase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    part_of FAR/SIN/STRIPAK complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in dendrite IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in dendrite ISO
    Inferred from Sequence Orthology
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    striatin-3
    Names
    cell cycle autoantigen SG2NA
    nuclear autoantigen
    s/G2 antigen
    striatin-3 35 kDa

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001172098.1NP_001165569.1  striatin-3 isoform 2

      See identical proteins and their annotated locations for NP_001165569.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks two alternate in-frame exons in the central coding region, compared to variant 1. The resulting isoform (2) lacks an internal segment, compared to isoform 1.
      Source sequence(s)
      AK040913, AK164967, AK164987, BB821090, BC138055
      Consensus CDS
      CCDS49063.1
      UniProtKB/TrEMBL
      B2RQS1, Q3TNV4
      Related
      ENSMUSP00000130184.2, ENSMUST00000169503.4
      Conserved Domains (4) summary
      COG2319
      Location:381710
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:390711
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:64190
      Striatin; Striatin family
      sd00039
      Location:400446
      7WD40; WD40 repeat [structural motif]
    2. NM_001364437.1NP_001351366.1  striatin-3 isoform 3

      Status: VALIDATED

      Source sequence(s)
      AC158404, AC159644
      Conserved Domains (3) summary
      cd00200
      Location:437758
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:447493
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:64190
      Striatin; Striatin family
    3. NM_052973.2NP_443205.1  striatin-3 isoform 1

      See identical proteins and their annotated locations for NP_443205.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript and encodes the longer isoform (1).
      Source sequence(s)
      AF307777, AK040913, AK164967, AK164987, BB821090, BC138055
      Consensus CDS
      CCDS36440.1
      UniProtKB/Swiss-Prot
      Q9ERG2
      UniProtKB/TrEMBL
      B2RQS1, Q3TNV4
      Related
      ENSMUSP00000013130.9, ENSMUST00000013130.15
      Conserved Domains (4) summary
      COG2319
      Location:465794
      WD40; WD40 repeat [General function prediction only]
      cd00200
      Location:474795
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      pfam08232
      Location:64190
      Striatin; Striatin family
      sd00039
      Location:484530
      7WD40; WD40 repeat [structural motif]

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000078.7 Reference GRCm39 C57BL/6J

      Range
      51655324..51743942 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036157706.1XP_036013599.1  striatin-3 isoform X5

      Conserved Domains (3) summary
      cd00200
      Location:391712
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:401447
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:65190
      Striatin; Striatin family
    2. XM_006516411.5XP_006516474.1  striatin-3 isoform X3

      Conserved Domains (3) summary
      cd00200
      Location:428749
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:438484
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:64190
      Striatin; Striatin family
    3. XM_006516412.5XP_006516475.1  striatin-3 isoform X4

      Conserved Domains (3) summary
      cd00200
      Location:427748
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:437483
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:64190
      Striatin; Striatin family
    4. XM_036157705.1XP_036013598.1  striatin-3 isoform X2

      Conserved Domains (3) summary
      cd00200
      Location:484805
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:494540
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:65190
      Striatin; Striatin family
    5. XM_036157704.1XP_036013597.1  striatin-3 isoform X1

      Conserved Domains (3) summary
      cd00200
      Location:531852
      WD40; WD40 domain, found in a number of eukaryotic proteins that cover a wide variety of functions including adaptor/regulatory modules in signal transduction, pre-mRNA processing and cytoskeleton assembly; typically contains a GH dipeptide 11-24 residues from ...
      sd00039
      Location:541587
      7WD40; WD40 repeat [structural motif]
      pfam08232
      Location:65190
      Striatin; Striatin family
    Support Center