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    Bcl2l13 BCL2-like 13 (apoptosis facilitator) [ Mus musculus (house mouse) ]

    Gene ID: 94044, updated on 31-Jan-2019

    Summary

    Official Symbol
    Bcl2l13provided by MGI
    Official Full Name
    BCL2-like 13 (apoptosis facilitator)provided by MGI
    Primary source
    MGI:MGI:2136959
    See related
    Ensembl:ENSMUSG00000009112
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mil1; Mil-1; BCL-RAMBO; E430016C20Rik
    Expression
    Ubiquitous expression in heart adult (RPKM 9.6), subcutaneous fat pad adult (RPKM 9.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Bcl2l13 in Genome Data Viewer
    Location:
    6 F1; 6 57.01 cM
    Exon count:
    7
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 6 NC_000072.6 (120836217..120892842)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 6 NC_000072.5 (120786248..120842860)

    Chromosome 6 - NC_000072.6Genomic Context describing neighboring genes Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit E1 Neighboring gene ribosomal protein S27 pseudogene Neighboring gene predicted gene, 38889 Neighboring gene ATPase, H+ transporting, lysosomal V1 subunit G1 pseudogene Neighboring gene BH3 interacting domain death agonist Neighboring gene microtubule associated monooxygenase, calponin and LIM domain containing 3 Neighboring gene predicted gene 9878

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Pathways from BioSystems

    • Legionellosis, organism-specific biosystem (from KEGG)
      Legionellosis, organism-specific biosystemLegionellosis is a potentially fatal infectious disease caused by the bacterium Legionella pneumophila and other legionella species. Two distinct clinical and epidemiological syndromes are associated...
    • Legionellosis, conserved biosystem (from KEGG)
      Legionellosis, conserved biosystemLegionellosis is a potentially fatal infectious disease caused by the bacterium Legionella pneumophila and other legionella species. Two distinct clinical and epidemiological syndromes are associated...
    • Mitophagy - animal, organism-specific biosystem (from KEGG)
      Mitophagy - animal, organism-specific biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...
    • Mitophagy - animal, conserved biosystem (from KEGG)
      Mitophagy - animal, conserved biosystemMitochondria act as the energy powerhouse of the cell, and are essential for eukaryotic cells to grow and function normally. However, deleterious byproducts of oxidative phosphorylation process calle...

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC38758

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    molecular_function ND
    No biological Data available
    more info
     
    Process Evidence Code Pubs
    apoptotic process RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    regulation of apoptotic process RCA
    inferred from Reviewed Computational Analysis
    more info
    PubMed 
    Component Evidence Code Pubs
    integral component of membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    integral component of membrane ISO
    Inferred from Sequence Orthology
    more info
     
    integral component of membrane ISS
    Inferred from Sequence or Structural Similarity
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion HDA PubMed 

    General protein information

    Preferred Names
    bcl-2-like protein 13
    Names
    bcl2-L-13
    mitochondria located 1 homolog
    protein Mil1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_153516.2NP_705736.1  bcl-2-like protein 13

      See identical proteins and their annotated locations for NP_705736.1

      Status: VALIDATED

      Source sequence(s)
      AC083894, BC029016
      Consensus CDS
      CCDS20485.1
      UniProtKB/Swiss-Prot
      P59017
      Related
      ENSMUSP00000009256.2, ENSMUST00000009256.3
      Conserved Domains (1) summary
      pfam00452
      Location:101197
      Bcl-2; Apoptosis regulator proteins, Bcl-2 family

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000072.6 Reference GRCm38.p4 C57BL/6J

      Range
      120836217..120892842
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_017321842.1XP_017177331.1  bcl-2-like protein 13 isoform X2

      Conserved Domains (1) summary
      pfam00452
      Location:65161
      Bcl-2; Apoptosis regulator proteins, Bcl-2 family
    2. XM_006506814.2XP_006506877.1  bcl-2-like protein 13 isoform X1

      Conserved Domains (1) summary
      pfam00452
      Location:67163
      Bcl-2; Apoptosis regulator proteins, Bcl-2 family

    Reference GRCm38.p4 129S1/SvImJ

    Genomic

    1. NT_039382.4 Reference GRCm38.p4 129S1/SvImJ

      Range
      461057..517459
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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