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    Pard3 par-3 family cell polarity regulator [ Mus musculus (house mouse) ]

    Gene ID: 93742, updated on 7-Sep-2021

    Summary

    Official Symbol
    Pard3provided by MGI
    Official Full Name
    par-3 family cell polarity regulatorprovided by MGI
    Primary source
    MGI:MGI:2135608
    See related
    Ensembl:ENSMUSG00000025812
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    P; PA; Asip; Par3; Phip; Par-3; Pard-3; Pard3a; AA960621; AI256638; D8Ertd580; D8Ertd580e
    Annotation information
    Note: Par3 (Gene ID: 112235) and Pard3 (Gene ID: 93742) share the Par3 symbol/alias in common. Par3 is a widely used alternative name for par-3 family cell polarity regulator (Pard3), which can be confused with the official symbol for pulmonary adenoma resistance 3 (Par3). [13 May 2019]
    Expression
    Ubiquitous expression in ovary adult (RPKM 7.1), bladder adult (RPKM 6.3) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Pard3 in Genome Data Viewer
    Location:
    8 E2; 8 74.66 cM
    Exon count:
    28
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (127790131..128338767)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (127063381..127612286)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (129587956..130136186)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 38574 Neighboring gene GABA(A) receptor-associated protein like 2 pseudogene 8_1688.1 Neighboring gene predicted gene, 53207 Neighboring gene predicted gene 9909 Neighboring gene predicted gene, 51558 Neighboring gene predicted gene, 32478 Neighboring gene predicted gene, 32532

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables lipid binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables phosphatidylinositol binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables phosphatidylinositol-3,4,5-trisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-3-phosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables phosphatidylinositol-4,5-bisphosphate binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables protein phosphatase binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within apical constriction IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in bicellular tight junction assembly ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in cell adhesion IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell division IEA
    Inferred from Electronic Annotation
    more info
     
    acts_upstream_of_or_within cell-cell adhesion IC
    Inferred by Curator
    more info
    PubMed 
    acts_upstream_of_or_within centrosome localization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in establishment of cell polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in establishment of centrosome localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in establishment of epithelial cell polarity ISO
    Inferred from Sequence Orthology
    more info
     
    involved_in establishment or maintenance of cell polarity TAS
    Traceable Author Statement
    more info
    PubMed 
    involved_in establishment or maintenance of epithelial cell apical/basal polarity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in microtubule cytoskeleton organization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    acts_upstream_of_or_within microtubule cytoskeleton organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in myelination in peripheral nervous system IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in negative regulation of peptidyl-threonine phosphorylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of myelination IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in positive regulation of receptor internalization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in protein localization IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    involved_in protein targeting to membrane ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within regulation of actin filament-based process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    involved_in regulation of cellular localization ISO
    Inferred from Sequence Orthology
    more info
     
    acts_upstream_of_or_within wound healing, spreading of cells IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    located_in Schmidt-Lanterman incisure IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in adherens junction IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in adherens junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in apical junction complex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in apical junction complex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in apical part of cell IDA
    Inferred from Direct Assay
    more info
     
    is_active_in apical plasma membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in axonal growth cone ISO
    Inferred from Sequence Orthology
    more info
     
    located_in bicellular tight junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in bicellular tight junction ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in cell cortex IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in cell cortex IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cell-cell junction IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cell-cell junction ISO
    Inferred from Sequence Orthology
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoskeleton IEA
    Inferred from Electronic Annotation
    more info
     
    located_in internode region of axon IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in lateral loop IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in neuronal cell body ISO
    Inferred from Sequence Orthology
    more info
     
    located_in plasma membrane ISO
    Inferred from Sequence Orthology
    more info
     
    part_of protein-containing complex ISO
    Inferred from Sequence Orthology
    more info
     
    located_in spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    partitioning defective 3 homolog
    Names
    atypical PKC isotype-specific-interacting protein
    ephrin-interacting protein
    par-3 (partitioning defective 3) homolog

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001013580.4NP_001013598.1  partitioning defective 3 homolog isoform 2

      See identical proteins and their annotated locations for NP_001013598.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2, also called PAR-3o2) differs in the 5' and 3' UTR and has multiple coding region differences compared to variant 5. These differences cause translation initiation at a downstream AUG and an isoform (2) with a shorter N-terminus and shorter and distinct C-terminus compared to isoform 5.
      Source sequence(s)
      AC105981, AC132321
      Consensus CDS
      CCDS40523.1
      UniProtKB/Swiss-Prot
      Q99NH2
      Related
      ENSMUSP00000125612.2, ENSMUST00000160717.8
      Conserved Domains (1) summary
      cd00992
      Location:330409
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    2. NM_001013581.3NP_001013599.1  partitioning defective 3 homolog isoform 1

      See identical proteins and their annotated locations for NP_001013599.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1, also called PAR-3o1) differs in the 5' and 3' UTR and has multiple coding region differences compared to variant 5. These differences cause translation initiation at a downstream AUG and an isoform (1) with a shorter N-terminus and shorter and distinct C-terminus compared to isoform 5.
      Source sequence(s)
      AC105981, AC132321
      Consensus CDS
      CCDS22789.1
      UniProtKB/Swiss-Prot
      Q99NH2
      UniProtKB/TrEMBL
      A0A0R4J1Y4
      Related
      ENSMUSP00000124162.2, ENSMUST00000162456.8
      Conserved Domains (1) summary
      cd00992
      Location:330409
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
    3. NM_001122850.2NP_001116322.1  partitioning defective 3 homolog isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 3' UTR and coding region compared to variant 5. The resulting isoform (4) has a shorter and distinct C-terminus compared to isoform 5.
      Source sequence(s)
      AC105981, AC132321, AC155818, AC165964
      Consensus CDS
      CCDS52712.1
      UniProtKB/TrEMBL
      A5D6P2, E9PYJ2
      Related
      ENSMUSP00000124319.2, ENSMUST00000162907.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:1146
      DUF3534; Domain of unknown function (DUF3534)
    4. NM_001309391.1NP_001296320.1  partitioning defective 3 homolog isoform 5

      See identical proteins and their annotated locations for NP_001296320.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (5) encodes isoform 5.
      Source sequence(s)
      BC090616
      Consensus CDS
      CCDS80945.1
      UniProtKB/TrEMBL
      A5D6P2
      Related
      ENSMUSP00000125453.2, ENSMUST00000160272.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:1146
      DUF3534; Domain of unknown function (DUF3534)
    5. NM_001309392.1NP_001296321.1  partitioning defective 3 homolog isoform 6

      See identical proteins and their annotated locations for NP_001296321.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (6) lacks an in-frame exon in the central coding region, compared to variant 5. The encoded isoform (6) is shorter than isoform 5.
      Source sequence(s)
      BC090616
      Consensus CDS
      CCDS80946.1
      UniProtKB/TrEMBL
      A5D6P2, B7ZNY3
      Related
      ENSMUSP00000026921.7, ENSMUST00000026921.13
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:1146
      DUF3534; Domain of unknown function (DUF3534)
    6. NM_001363431.1NP_001350360.1  partitioning defective 3 homolog isoform 7

      Status: VALIDATED

      Description
      Transcript Variant: This variant (7) uses an alternate in-frame splice junction compared to variant 5. The resulting isoform (7) has the same N- and C-termini but is shorter compared to isoform 5.
      Source sequence(s)
      AC102819, AC105981, AC132321, AC155818, AC165964
      Related
      ENSMUSP00000124718.2, ENSMUST00000162665.8
      Conserved Domains (3) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam06495
      Location:11171187
      Transformer; Fruit fly transformer protein
      pfam12053
      Location:1146
      DUF3534; Domain of unknown function (DUF3534)
    7. NM_001363432.1NP_001350361.1  partitioning defective 3 homolog isoform 8

      Status: VALIDATED

      Description
      Transcript Variant: This variant (8) represents the longest transcript and encodes the longest isoform (8).
      Source sequence(s)
      AC102819, AC105981, AC132321, AC155818, AC165964
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:1146
      DUF3534; Domain of unknown function (DUF3534)
    8. NM_033620.2NP_296369.2  partitioning defective 3 homolog isoform 3

      See identical proteins and their annotated locations for NP_296369.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate in-frame splice site in the central coding region, compared to variant 5. The encoded isoform (3) is shorter than isoform 5.
      Source sequence(s)
      BC090616
      Consensus CDS
      CCDS22788.1
      UniProtKB/TrEMBL
      A5D6P2, G3XA13
      Related
      ENSMUSP00000124282.2, ENSMUST00000162309.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:1146
      DUF3534; Domain of unknown function (DUF3534)

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      127790131..128338767
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531520.3XP_006531583.1  partitioning defective 3 homolog isoform X1

      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    2. XM_006531523.3XP_006531586.1  partitioning defective 3 homolog isoform X2

      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    3. XM_006531524.3XP_006531587.1  partitioning defective 3 homolog isoform X3

      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    4. XM_006531527.3XP_006531590.1  partitioning defective 3 homolog isoform X5

      Conserved Domains (3) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam06495
      Location:11201190
      Transformer; Fruit fly transformer protein
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    5. XM_006531529.3XP_006531592.1  partitioning defective 3 homolog isoform X10

      Related
      ENSMUSP00000125450.2, ENSMUST00000162602.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    6. XM_006531530.3XP_006531593.1  partitioning defective 3 homolog isoform X11

      Related
      ENSMUSP00000124934.2, ENSMUST00000159537.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    7. XM_030243870.1XP_030099730.1  partitioning defective 3 homolog isoform X13

      Related
      ENSMUSP00000124141.2, ENSMUST00000160581.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    8. XM_006531532.3XP_006531595.1  partitioning defective 3 homolog isoform X14

      Related
      ENSMUSP00000125064.2, ENSMUST00000161355.8
      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    9. XM_006531531.3XP_006531594.1  partitioning defective 3 homolog isoform X12

      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    10. XM_006531533.3XP_006531596.1  partitioning defective 3 homolog isoform X15

      Conserved Domains (2) summary
      cd00992
      Location:465544
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    11. XM_006531526.3XP_006531589.1  partitioning defective 3 homolog isoform X4

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    12. XM_030243868.1XP_030099728.1  partitioning defective 3 homolog isoform X8

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    13. XM_030243867.1XP_030099727.1  partitioning defective 3 homolog isoform X6

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    14. XM_030243869.1XP_030099729.1  partitioning defective 3 homolog isoform X9

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    15. XM_036154397.1XP_036010290.1  partitioning defective 3 homolog isoform X7

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    16. XM_030243872.1XP_030099732.1  partitioning defective 3 homolog isoform X17

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
    17. XM_030243871.1XP_030099731.1  partitioning defective 3 homolog isoform X16

      Conserved Domains (2) summary
      cd00992
      Location:437516
      PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
      pfam12053
      Location:283
      DUF3534; N-terminal of Par3 and HAL proteins
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