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    AP1G2 adaptor related protein complex 1 subunit gamma 2 [ Homo sapiens (human) ]

    Gene ID: 8906, updated on 17-Jun-2024

    Summary

    Official Symbol
    AP1G2provided by HGNC
    Official Full Name
    adaptor related protein complex 1 subunit gamma 2provided by HGNC
    Primary source
    HGNC:HGNC:556
    See related
    Ensembl:ENSG00000213983 MIM:603534; AllianceGenome:HGNC:556
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    G2AD
    Summary
    Adaptins are important components of clathrin-coated vesicles transporting ligand-receptor complexes from the plasma membrane or from the trans-Golgi network to lysosomes. The adaptin family of proteins is composed of four classes of molecules named alpha, beta-, beta prime- and gamma- adaptins. Adaptins, together with medium and small subunits, form a heterotetrameric complex called an adaptor, whose role is to promote the formation of clathrin-coated pits and vesicles. The protein encoded by this gene is a gamma-adaptin protein and it belongs to the adaptor complexes large subunits family. This protein along with the complex is thought to function at some trafficking step in the complex pathways between the trans-Golgi network and the cell surface. [provided by RefSeq, Aug 2017]
    Expression
    Ubiquitous expression in skin (RPKM 20.0), lymph node (RPKM 17.8) and 25 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See AP1G2 in Genome Data Viewer
    Location:
    14q11.2
    Exon count:
    21
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (23559567..23567791, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (17760126..17768361, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (24028776..24037000, complement)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene NANOG-H3K27ac hESC enhancer GRCh37_chr14:23938675-23939615 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:23951280-23952037 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:23952038-23952794 Neighboring gene neuroguidin Neighboring gene OCT4-NANOG-H3K27ac hESC enhancer GRCh37_chr14:23963206-23963906 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:23993935-23994786 Neighboring gene thiamine triphosphatase Neighboring gene uncharacterized LOC124903289 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:24001492-24001992 Neighboring gene OCT4-NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:24006625-24007504 Neighboring gene zinc finger homeobox 2 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:24014522-24015146 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:24017019-24017642 Neighboring gene NANOG-H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:24019766-24020428 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5610 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8172 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:24024860-24025794 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8174 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:24031286-24031786 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:24031787-24032287 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8175 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8176 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5611 Neighboring gene AP1G2 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 5612 Neighboring gene H3K4me1 hESC enhancer GRCh37_chr14:24046010-24046770 Neighboring gene H3K27ac-H3K4me1 hESC enhancer GRCh37_chr14:24054355-24054854 Neighboring gene junctophilin 4 Neighboring gene Sharpr-MPRA regulatory region 10629 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 8178 Neighboring gene dehydrogenase/reductase 2

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Phenotypes

    EBI GWAS Catalog

    Description
    GWAS for discovery and replication of genetic loci associated with sudden cardiac arrest in patients with coronary artery disease.
    EBI GWAS Catalog

    HIV-1 interactions

    Replication interactions

    Interaction Pubs
    Knockdown of adaptor-related protein complex 1, gamma 2 subunit (AP1G2) by siRNA inhibits the early stages of HIV-1 replication in 293T cells infected with VSV-G pseudotyped HIV-1 PubMed

    Protein interactions

    Protein Gene Interaction Pubs
    Envelope transmembrane glycoprotein gp41 env The highly conserved C-terminal dileucine motif (residues 851-856) in the cytosolic domain of HIV-1 gp41 interacts with clathrin-associated AP-1 adaptor complexes PubMed
    env The cytoplasmic domain (residues 707-856) of HIV-1 gp41 interacts with whole clathrin-associated AP-1 and AP-2 adaptor complexes PubMed
    Nef nef Adaptor-related protein complex 1 (AP-1) is necessary for cross-presentation by MHC-I HLA-A and HLA-B molecules containing a cytoplasmic tail tyrosine signal and that HIV-1 Nef inhibits the cross-presentation in antigen-presenting cells PubMed
    nef Exogenous Nef and TNF-alpha synergistically activate NF-kappaB and AP-1 resulting in enhancing viral replication in both chronically infected promonocytic cells and acutely infected primary macrophages PubMed
    nef HIV-1 Nef stabilizes AP-1 complexes on endosomal membranes after ADP-ribosylation factor-1 (ARF1) -dependent attachment PubMed
    nef The dileucine motif (residues 164-165) in HIV-1 Nef is required for binding to AP-1 complexes and stabilizing their association with membranes PubMed
    nef A leucine-based motif near the C-terminus of HIV-1 Nef interacts with AP-1 complexes; residues 164 and 165 in Nef are required for the interaction with AP-1 PubMed

    Go to the HIV-1, Human Interaction Database

    Pathways from PubChem

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables clathrin adaptor activity IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in Golgi to vacuole transport IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in intracellular protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in vesicle-mediated transport NAS
    Non-traceable Author Statement
    more info
    PubMed 
    Component Evidence Code Pubs
    part_of AP-1 adaptor complex IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    part_of AP-1 adaptor complex TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in Golgi apparatus TAS
    Traceable Author Statement
    more info
    PubMed 
    located_in Golgi membrane TAS
    Traceable Author Statement
    more info
     
    located_in Golgi-associated vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endosome membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in transport vesicle IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    AP-1 complex subunit gamma-like 2
    Names
    adaptor related protein complex 1 gamma 2 subunit
    clathrin-associated/assembly/adaptor protein, large, gamma-2
    gamma2-adaptin

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    Genomic

    1. NG_011937.1 RefSeqGene

      Range
      5280..13504
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001282474.2NP_001269403.1  AP-1 complex subunit gamma-like 2 isoform 2

      See identical proteins and their annotated locations for NP_001269403.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (3) uses an alternate 5' exon structure and thus differs in the 5' UTR and 5' coding region compared to variant 1. These differences cause translation initiation at a downstream AUG and result in an isoform (2) with a shorter N-terminus, compared to isoform 1.
      Source sequence(s)
      AI497879, BG701521, BX161425
      UniProtKB/TrEMBL
      Q86U03
      Related
      ENST00000460049.6
      Conserved Domains (2) summary
      smart00809
      Location:291399
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:1194
      Adaptin_N; Adaptin N terminal region
    2. NM_001282475.2NP_001269404.1  AP-1 complex subunit gamma-like 2 isoform 3

      See identical proteins and their annotated locations for NP_001269404.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR and has multiple differences in the coding region but maintains the reading frame, compared to variant 1. This variant encodes isoform 3, which is shorter than isoform 1.
      Source sequence(s)
      AL135999, BC051833, BI918958, H41406
      UniProtKB/TrEMBL
      Q86V28
      Related
      ENST00000535852.6
      Conserved Domains (2) summary
      smart00809
      Location:600708
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:1503
      Adaptin_N; Adaptin N terminal region
    3. NM_001354673.2NP_001341602.1  AP-1 complex subunit gamma-like 2 isoform 4

      Status: REVIEWED

      Source sequence(s)
      AK304682, AL135999
      UniProtKB/TrEMBL
      B4E3E1
      Conserved Domains (2) summary
      pfam01602
      Location:1446
      Adaptin_N; Adaptin N terminal region
      pfam02883
      Location:543651
      Alpha_adaptinC2; Adaptin C-terminal domain
    4. NM_001354674.2NP_001341603.1  AP-1 complex subunit gamma-like 2 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK304682, AL135999
      UniProtKB/TrEMBL
      Q86U03
      Conserved Domains (2) summary
      smart00809
      Location:291399
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:1194
      Adaptin_N; Adaptin N terminal region
    5. NM_001354675.2NP_001341604.1  AP-1 complex subunit gamma-like 2 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK304682, AL135999
      UniProtKB/TrEMBL
      Q86U03
      Related
      ENST00000465445.6
      Conserved Domains (2) summary
      smart00809
      Location:291399
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:1194
      Adaptin_N; Adaptin N terminal region
    6. NM_001354677.2NP_001341606.1  AP-1 complex subunit gamma-like 2 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK304682, AL135999
      UniProtKB/TrEMBL
      Q86U03
      Conserved Domains (2) summary
      smart00809
      Location:291399
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:1194
      Adaptin_N; Adaptin N terminal region
    7. NM_001354681.2NP_001341610.1  AP-1 complex subunit gamma-like 2 isoform 2

      Status: REVIEWED

      Source sequence(s)
      AK304682, AL135999
      UniProtKB/TrEMBL
      Q86U03
      Conserved Domains (2) summary
      smart00809
      Location:291399
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:1194
      Adaptin_N; Adaptin N terminal region
    8. NM_003917.5NP_003908.1  AP-1 complex subunit gamma-like 2 isoform 1

      See identical proteins and their annotated locations for NP_003908.1

      Status: REVIEWED

      Description
      Transcript Variant: This variant (1) encodes the longest isoform (1).
      Source sequence(s)
      AB015318, BG701521, BQ073124
      Consensus CDS
      CCDS9602.1
      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
      Related
      ENSP00000380309.3, ENST00000397120.8
      Conserved Domains (2) summary
      smart00809
      Location:672780
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24575
      Adaptin_N; Adaptin N terminal region

    RNA

    1. NR_148937.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (9) is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK304682, AL135999
    2. NR_148938.2 RNA Sequence

      Status: REVIEWED

      Description
      Transcript Variant: This variant (11) is represented as non-coding because the use of the 5'-most expected translational start codon renders the transcript a candidate for nonsense-mediated mRNA decay (NMD).
      Source sequence(s)
      AK304682, AL135999

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      23559567..23567791 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_047431859.1XP_047287815.1  AP-1 complex subunit gamma-like 2 isoform X8

    2. XM_005268173.4XP_005268230.1  AP-1 complex subunit gamma-like 2 isoform X6

      See identical proteins and their annotated locations for XP_005268230.1

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
      Conserved Domains (2) summary
      smart00809
      Location:672780
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24575
      Adaptin_N; Adaptin N terminal region
    3. XM_005268170.4XP_005268227.1  AP-1 complex subunit gamma-like 2 isoform X2

      See identical proteins and their annotated locations for XP_005268227.1

      Conserved Domains (2) summary
      smart00809
      Location:729837
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24632
      Adaptin_N; Adaptin N terminal region
    4. XM_047431857.1XP_047287813.1  AP-1 complex subunit gamma-like 2 isoform X8

    5. XM_047431851.1XP_047287807.1  AP-1 complex subunit gamma-like 2 isoform X5

    6. XM_005268167.4XP_005268224.1  AP-1 complex subunit gamma-like 2 isoform X2

      See identical proteins and their annotated locations for XP_005268224.1

      Conserved Domains (2) summary
      smart00809
      Location:729837
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24632
      Adaptin_N; Adaptin N terminal region
    7. XM_006720301.4XP_006720364.1  AP-1 complex subunit gamma-like 2 isoform X2

      See identical proteins and their annotated locations for XP_006720364.1

      Conserved Domains (2) summary
      smart00809
      Location:729837
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24632
      Adaptin_N; Adaptin N terminal region
    8. XM_047431858.1XP_047287814.1  AP-1 complex subunit gamma-like 2 isoform X8

    9. XM_047431855.1XP_047287811.1  AP-1 complex subunit gamma-like 2 isoform X6

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
    10. XM_047431852.1XP_047287808.1  AP-1 complex subunit gamma-like 2 isoform X5

    11. XM_005268168.6XP_005268225.1  AP-1 complex subunit gamma-like 2 isoform X2

      See identical proteins and their annotated locations for XP_005268225.1

      Conserved Domains (2) summary
      smart00809
      Location:729837
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24632
      Adaptin_N; Adaptin N terminal region
    12. XM_047431856.1XP_047287812.1  AP-1 complex subunit gamma-like 2 isoform X7

    13. XM_047431850.1XP_047287806.1  AP-1 complex subunit gamma-like 2 isoform X4

    14. XM_011537283.4XP_011535585.2  AP-1 complex subunit gamma-like 2 isoform X3

    15. XM_047431849.1XP_047287805.1  AP-1 complex subunit gamma-like 2 isoform X1

    16. XM_005268172.4XP_005268229.1  AP-1 complex subunit gamma-like 2 isoform X6

      See identical proteins and their annotated locations for XP_005268229.1

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
      Conserved Domains (2) summary
      smart00809
      Location:672780
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24575
      Adaptin_N; Adaptin N terminal region
    17. XM_047431853.1XP_047287809.1  AP-1 complex subunit gamma-like 2 isoform X5

    18. XM_005268169.4XP_005268226.1  AP-1 complex subunit gamma-like 2 isoform X2

      See identical proteins and their annotated locations for XP_005268226.1

      Conserved Domains (2) summary
      smart00809
      Location:729837
      Alpha_adaptinC2; Adaptin C-terminal domain
      pfam01602
      Location:24632
      Adaptin_N; Adaptin N terminal region
    19. XM_047431854.1XP_047287810.1  AP-1 complex subunit gamma-like 2 isoform X6

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
      Related
      ENSP00000312442.5, ENST00000308724.9
    20. XM_047431863.1XP_047287819.1  AP-1 complex subunit gamma-like 2 isoform X12

      UniProtKB/TrEMBL
      B4E3E1
    21. XM_047431866.1XP_047287822.1  AP-1 complex subunit gamma-like 2 isoform X15

    22. XM_047431860.1XP_047287816.1  AP-1 complex subunit gamma-like 2 isoform X9

    23. XM_047431861.1XP_047287817.1  AP-1 complex subunit gamma-like 2 isoform X10

    24. XM_047431868.1XP_047287824.1  AP-1 complex subunit gamma-like 2 isoform X16

    25. XM_047431867.1XP_047287823.1  AP-1 complex subunit gamma-like 2 isoform X16

    26. XM_047431864.1XP_047287820.1  AP-1 complex subunit gamma-like 2 isoform X13

    27. XM_047431865.1XP_047287821.1  AP-1 complex subunit gamma-like 2 isoform X14

    28. XM_047431862.1XP_047287818.1  AP-1 complex subunit gamma-like 2 isoform X11

    29. XM_047431869.1XP_047287825.1  AP-1 complex subunit gamma-like 2 isoform X16

    30. XM_047431870.1XP_047287826.1  AP-1 complex subunit gamma-like 2 isoform X17

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      17760126..17768361 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054376895.1XP_054232870.1  AP-1 complex subunit gamma-like 2 isoform X8

    2. XM_054376889.1XP_054232864.1  AP-1 complex subunit gamma-like 2 isoform X6

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
    3. XM_054376881.1XP_054232856.1  AP-1 complex subunit gamma-like 2 isoform X2

    4. XM_054376893.1XP_054232868.1  AP-1 complex subunit gamma-like 2 isoform X8

    5. XM_054376886.1XP_054232861.1  AP-1 complex subunit gamma-like 2 isoform X5

    6. XM_054376879.1XP_054232854.1  AP-1 complex subunit gamma-like 2 isoform X2

    7. XM_054376883.1XP_054232858.1  AP-1 complex subunit gamma-like 2 isoform X2

    8. XM_054376894.1XP_054232869.1  AP-1 complex subunit gamma-like 2 isoform X8

    9. XM_054376890.1XP_054232865.1  AP-1 complex subunit gamma-like 2 isoform X6

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
    10. XM_054376887.1XP_054232862.1  AP-1 complex subunit gamma-like 2 isoform X5

    11. XM_054376880.1XP_054232855.1  AP-1 complex subunit gamma-like 2 isoform X2

    12. XM_054376892.1XP_054232867.1  AP-1 complex subunit gamma-like 2 isoform X7

    13. XM_054376885.1XP_054232860.1  AP-1 complex subunit gamma-like 2 isoform X4

    14. XM_054376884.1XP_054232859.1  AP-1 complex subunit gamma-like 2 isoform X3

    15. XM_054376878.1XP_054232853.1  AP-1 complex subunit gamma-like 2 isoform X1

    16. XM_054376891.1XP_054232866.1  AP-1 complex subunit gamma-like 2 isoform X6

      UniProtKB/Swiss-Prot
      D3DS51, O75504, O75843
    17. XM_054376888.1XP_054232863.1  AP-1 complex subunit gamma-like 2 isoform X5

    18. XM_054376882.1XP_054232857.1  AP-1 complex subunit gamma-like 2 isoform X2

    19. XM_054376896.1XP_054232871.1  AP-1 complex subunit gamma-like 2 isoform X18

    20. XM_054376898.1XP_054232873.1  AP-1 complex subunit gamma-like 2 isoform X19

      UniProtKB/TrEMBL
      B4E3E1, Q86V28
    21. XM_054376901.1XP_054232876.1  AP-1 complex subunit gamma-like 2 isoform X12

      UniProtKB/TrEMBL
      B4E3E1
    22. XM_054376904.1XP_054232879.1  AP-1 complex subunit gamma-like 2 isoform X15

    23. XM_054376897.1XP_054232872.1  AP-1 complex subunit gamma-like 2 isoform X9

    24. XM_054376899.1XP_054232874.1  AP-1 complex subunit gamma-like 2 isoform X10

    25. XM_054376906.1XP_054232881.1  AP-1 complex subunit gamma-like 2 isoform X16

    26. XM_054376905.1XP_054232880.1  AP-1 complex subunit gamma-like 2 isoform X16

    27. XM_054376902.1XP_054232877.1  AP-1 complex subunit gamma-like 2 isoform X13

    28. XM_054376903.1XP_054232878.1  AP-1 complex subunit gamma-like 2 isoform X14

    29. XM_054376900.1XP_054232875.1  AP-1 complex subunit gamma-like 2 isoform X11

    30. XM_054376907.1XP_054232882.1  AP-1 complex subunit gamma-like 2 isoform X16

    31. XM_054376908.1XP_054232883.1  AP-1 complex subunit gamma-like 2 isoform X17

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_080545.1: Suppressed sequence

      Description
      NM_080545.1: This RefSeq was temporarily suppressed because insufficient data to support this transcript currently exist.