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    OPI3 bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase [ Saccharomyces cerevisiae S288C ]

    Gene ID: 853536, updated on 5-Aug-2018

    Summary

    Gene symbol
    OPI3
    Gene description
    bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase
    Primary source
    SGD:S000003834
    Locus tag
    YJR073C
    Gene type
    protein coding
    RNA name
    bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase
    RefSeq status
    REVIEWED
    Organism
    Saccharomyces cerevisiae S288C (strain: S288C)
    Lineage
    Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes; Saccharomycetales; Saccharomycetaceae; Saccharomyces
    Also known as
    PEM2

    Genomic context

    See OPI3 in Genome Data Viewer
    Location:
    chromosome: X
    Exon count:
    1
    Sequence:
    Chromosome: X; NC_001142.9 (572315..572935, complement)

    Chromosome X - NC_001142.9Genomic Context describing neighboring genes Neighboring gene Lia1p Neighboring gene GTPase NPA3 Neighboring gene Ran GTPase-binding protein MOG1 Neighboring gene alpha-1,6-mannosyltransferase

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Homology

    • Homologs of the OPI3 gene: The OPI3 gene is conserved in human, chimpanzee, Rhesus monkey, dog, cow, mouse, rat, chicken, zebrafish, S.cerevisiae, K.lactis, E.gossypii, S.pombe, M.oryzae, N.crassa, and frog.

    Gene Ontology Provided by GO

    Process Evidence Code Pubs
    lipid metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    methylation IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylcholine biosynthetic process IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    phosphatidylcholine biosynthetic process IDA
    Inferred from Direct Assay
    more info
    PubMed 
    phosphatidylcholine biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    phosphatidylcholine biosynthetic process IGI
    Inferred from Genetic Interaction
    more info
    PubMed 
    phosphatidylcholine biosynthetic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    phospholipid biosynthetic process IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    cell periphery HDA PubMed 
    endoplasmic reticulum HDA PubMed 
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     
    endoplasmic reticulum membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    integral component of membrane ISM
    Inferred from Sequence Model
    more info
    PubMed 
    membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrial membrane IEA
    Inferred from Electronic Annotation
    more info
     
    mitochondrion HDA PubMed 
    mitochondrion IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase
    NP_012607.1
    • Methylene-fatty-acyl-phospholipid synthase; catalyzes the last two steps in phosphatidylcholine biosynthesis; also known as phospholipid methyltransferase

    NCBI Reference Sequences (RefSeq)

    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_001142.9 Reference assembly

      Range
      572315..572935 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_001181731.1NP_012607.1  TPA: bifunctional phosphatidyl-N-methylethanolamine N-methyltransferase/phosphatidyl-N-dimethylethanolamine N-methyltransferase [Saccharomyces cerevisiae S288C]

      See identical proteins and their annotated locations for NP_012607.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      P05375
      Conserved Domains (1) summary
      pfam04191
      Location:100200
      PEMT; Phospholipid methyltransferase
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