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    Nlrp4c NLR family, pyrin domain containing 4C [ Mus musculus (house mouse) ]

    Gene ID: 83564, updated on 16-Oct-2021

    Summary

    Official Symbol
    Nlrp4cprovided by MGI
    Official Full Name
    NLR family, pyrin domain containing 4Cprovided by MGI
    Primary source
    MGI:MGI:1890518
    See related
    Ensembl:ENSMUSG00000034690
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Rnh2; Nalp4c; Nalp-alpha
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See Nlrp4c in Genome Data Viewer
    Location:
    7; 7 A1
    Exon count:
    10
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 7 NC_000073.7 (6048160..6108148)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 7 NC_000073.6 (6045161..6105149)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 7 NC_000073.5 (5996763..6056751)

    Chromosome 7 - NC_000073.7Genomic Context describing neighboring genes Neighboring gene protein tyrosine phosphatase 4a1 pseudogene Neighboring gene RIKEN cDNA 4933402C05 gene Neighboring gene crumbs homolog 1 pseudogene Neighboring gene predicted gene, 18758 Neighboring gene zinc finger protein 787 Neighboring gene predicted gene, 36371

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Pathways from PubChem

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables ATP binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables molecular_function ND
    No biological Data available
    more info
     
    enables nucleotide binding IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    involved_in biological_process ND
    No biological Data available
    more info
     
    acts_upstream_of_or_within inflammatory response IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    NACHT, LRR and PYD domains-containing protein 4C
    Names
    NACHT, leucine rich repeat and PYD containing 4C
    VNACHT, leucine rich repeat and PYD containing 4C
    ribonuclease/angiogenin inhibitor 2

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_031389.2NP_113566.2  NACHT, LRR and PYD domains-containing protein 4C

      See identical proteins and their annotated locations for NP_113566.2

      Status: VALIDATED

      Source sequence(s)
      AK166817, AY596194
      Consensus CDS
      CCDS51988.1
      UniProtKB/Swiss-Prot
      Q3TKR3
      Related
      ENSMUSP00000046503.6, ENSMUST00000037728.13
      Conserved Domains (5) summary
      COG4886
      Location:742960
      LRR; Leucine-rich repeat (LRR) protein [Transcription]
      cd00116
      Location:689953
      LRR_RI; Leucine-rich repeats (LRRs), ribonuclease inhibitor (RI)-like subfamily. LRRs are 20-29 residue sequence motifs present in many proteins that participate in protein-protein interactions and have different functions and cellular locations. LRRs correspond ...
      cd08320
      Location:1092
      Pyrin_NALPs; Pyrin death domain found in NALP proteins
      sd00033
      Location:749776
      LRR_RI; leucine-rich repeat [structural motif]
      pfam05729
      Location:148317
      NACHT; NACHT domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000073.7 Reference GRCm39 C57BL/6J

      Range
      6048160..6108148
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)
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