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    Tdrd1 tudor domain containing 1 [ Mus musculus (house mouse) ]

    Gene ID: 83561, updated on 5-Aug-2018

    Summary

    Official Symbol
    Tdrd1provided by MGI
    Official Full Name
    tudor domain containing 1provided by MGI
    Primary source
    MGI:MGI:1933218
    See related
    Ensembl:ENSMUSG00000025081 Vega:OTTMUSG00000028359
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    MTR-1
    Expression
    Biased expression in testis adult (RPKM 23.7) and limb E14.5 (RPKM 0.9) See more
    Orthologs

    Genomic context

    See Tdrd1 in Genome Data Viewer
    Location:
    19; 19 D2
    Exon count:
    29
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 19 NC_000085.6 (56826171..56870012)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 19 NC_000085.5 (56900699..56944502)

    Chromosome 19 - NC_000085.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 32718 Neighboring gene macrophage migration inhibitory factor, pseudogene 9 Neighboring gene coiled-coil domain containing 186 Neighboring gene von Willebrand factor A domain containing 2 Neighboring gene actin filament associated protein 1-like 2 Neighboring gene predicted gene, 38597

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    DNA methylation involved in gamete generation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    cell differentiation IEA
    Inferred from Electronic Annotation
    more info
     
    gene silencing by RNA IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    germ cell development IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    meiotic cell cycle IEA
    Inferred from Electronic Annotation
    more info
     
    multicellular organism development IEA
    Inferred from Electronic Annotation
    more info
     
    piRNA metabolic process IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    spermatogenesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    P granule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    chromatoid body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    pi-body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    ribonucleoprotein complex IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    tudor domain-containing protein 1

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001002238.2NP_001002238.1  tudor domain-containing protein 1

      See identical proteins and their annotated locations for NP_001002238.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) differs in the 5' UTR compared to variant 3. All four variants encode the same protein.
      Source sequence(s)
      AC125150, AC158549
      Consensus CDS
      CCDS29922.1
      UniProtKB/Swiss-Prot
      Q99MV1
      Related
      ENSMUSP00000107233.1, OTTMUSP00000035796, ENSMUST00000111606.7, OTTMUST00000070294
      Conserved Domains (3) summary
      cd04508
      Location:760805
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:487606
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    2. NM_001002240.2NP_001002240.1  tudor domain-containing protein 1

      See identical proteins and their annotated locations for NP_001002240.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 3. All four variants encode the same protein.
      Source sequence(s)
      AC125150, AC158549
      Consensus CDS
      CCDS29922.1
      UniProtKB/Swiss-Prot
      Q99MV1
      Related
      ENSMUSP00000077785.4, OTTMUSP00000035797, ENSMUST00000078723.10, OTTMUST00000070295
      Conserved Domains (3) summary
      cd04508
      Location:760805
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:487606
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    3. NM_001002241.2NP_001002241.1  tudor domain-containing protein 1

      See identical proteins and their annotated locations for NP_001002241.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) represents the longest transcript. All four variants encode the same protein.
      Source sequence(s)
      AC125150, AC158549
      Consensus CDS
      CCDS29922.1
      UniProtKB/Swiss-Prot
      Q99MV1
      Related
      ENSMUSP00000107231.1, OTTMUSP00000035798, ENSMUST00000111604.1, OTTMUST00000070296
      Conserved Domains (3) summary
      cd04508
      Location:760805
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:487606
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    4. NM_031387.3NP_113564.2  tudor domain-containing protein 1

      See identical proteins and their annotated locations for NP_113564.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) differs in the 5' UTR compared to variant 3. All four variants encode the same protein.
      Source sequence(s)
      AC125150, AK029806
      Consensus CDS
      CCDS29922.1
      UniProtKB/Swiss-Prot
      Q99MV1
      Related
      ENSMUSP00000112786.1, OTTMUSP00000035795, ENSMUST00000121249.7, OTTMUST00000070293
      Conserved Domains (3) summary
      cd04508
      Location:760805
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:487606
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000085.6 Reference GRCm38.p4 C57BL/6J

      Range
      56826171..56870012
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006527473.1XP_006527536.1  tudor domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006527536.1

      Conserved Domains (3) summary
      cd04508
      Location:761806
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:488607
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    2. XM_006527478.1XP_006527541.1  tudor domain-containing protein 1 isoform X2

      Conserved Domains (3) summary
      cd04508
      Location:761806
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:488607
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    3. XM_006527475.3XP_006527538.1  tudor domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006527538.1

      Conserved Domains (3) summary
      cd04508
      Location:761806
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:488607
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    4. XM_006527474.1XP_006527537.1  tudor domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006527537.1

      Conserved Domains (3) summary
      cd04508
      Location:761806
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:488607
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    5. XM_006527476.2XP_006527539.1  tudor domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006527539.1

      Conserved Domains (3) summary
      cd04508
      Location:761806
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:488607
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    6. XM_006527477.3XP_006527540.1  tudor domain-containing protein 1 isoform X1

      See identical proteins and their annotated locations for XP_006527540.1

      Conserved Domains (3) summary
      cd04508
      Location:761806
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:488607
      TUDOR; Tudor domain
      pfam01753
      Location:163199
      zf-MYND; MYND finger
    7. XM_006527479.3XP_006527542.1  tudor domain-containing protein 1 isoform X3

      Conserved Domains (3) summary
      cd04508
      Location:656701
      TUDOR; Tudor domains are found in many eukaryotic organisms and have been implicated in protein-protein interactions in which methylated protein substrates bind to these domains. For example, the Tudor domain of Survival of Motor Neuron (SMN) binds to ...
      pfam00567
      Location:381502
      TUDOR; Tudor domain
      pfam01753
      Location:5894
      zf-MYND; MYND finger
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