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    Rrbp1 ribosome binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 81910, updated on 23-Jun-2021

    Summary

    Official Symbol
    Rrbp1provided by MGI
    Official Full Name
    ribosome binding protein 1provided by MGI
    Primary source
    MGI:MGI:1932395
    See related
    Ensembl:ENSMUSG00000027422
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    mR; mRR; p18; p180; ES/13; mRRp0; mRRp1; mRRp2; ES/130; mRRp10; mRRp41; mRRp47; mRRp1.8; mRRp15a; mRRp15b; mRRp5.4; mRRp16.8; mKIAA1398; 1700087N07Rik; 5730465C04Rik
    Expression
    Ubiquitous expression in placenta adult (RPKM 37.3), liver E18 (RPKM 30.5) and 28 other tissues See more
    Orthologs
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    Genomic context

    See Rrbp1 in Genome Data Viewer
    Location:
    2; 2 G1
    Exon count:
    27
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 2 NC_000068.8 (143789315..143853216, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 2 NC_000068.7 (143947395..144011296, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 2 NC_000068.6 (143773131..143836999, complement)

    Chromosome 2 - NC_000068.8Genomic Context describing neighboring genes Neighboring gene beaded filament structural protein 1, in lens-CP94 Neighboring gene predicted gene 11686 Neighboring gene destrin Neighboring gene predicted gene, 33804 Neighboring gene predicted gene, 54119 Neighboring gene BANF family member 2 Neighboring gene barrier to autointegration factor 2, opposite strand Neighboring gene predicted gene, 53188

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     
    is_active_in integral component of endoplasmic reticulum membrane IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in integral component of membrane IEA
    Inferred from Electronic Annotation
    more info
     
    located_in membrane IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    ribosome-binding protein 1
    Names
    RRp
    mRRp
    ribosome receptor protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024281.2NP_077243.2  ribosome-binding protein 1 isoform a

      Status: VALIDATED

      Source sequence(s)
      AK019964, AK039114, AL929550, BE943663, CK787870, W75337
      Consensus CDS
      CCDS38252.1
      UniProtKB/Swiss-Prot
      Q99PL5
      UniProtKB/TrEMBL
      A2AVJ7, Q8CAB9
      Related
      ENSMUSP00000016072.6, ENSMUST00000016072.12
      Conserved Domains (4) summary
      PRK02224
      Location:9681448
      PRK02224; chromosome segregation protein; Provisional
      pfam00261
      Location:8331081
      Tropomyosin; Tropomyosin
      pfam05104
      Location:33171
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
      cl02488
      Location:8771071
      SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    2. NM_133626.2NP_598329.1  ribosome-binding protein 1 isoform b

      See identical proteins and their annotated locations for NP_598329.1

      Status: VALIDATED

      Source sequence(s)
      AK039114, AL929550, BQ033142
      Consensus CDS
      CCDS38253.1
      UniProtKB/Swiss-Prot
      Q99PL5
      UniProtKB/TrEMBL
      Q8CAB9
      Related
      ENSMUSP00000040560.6, ENSMUST00000037875.6
      Conserved Domains (1) summary
      pfam05104
      Location:33171
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000068.8 Reference GRCm39 C57BL/6J

      Range
      143789315..143853216 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006500441.2XP_006500504.1  ribosome-binding protein 1 isoform X2

      Conserved Domains (1) summary
      TIGR02168
      Location:155857
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    2. XM_006500440.2XP_006500503.1  ribosome-binding protein 1 isoform X1

      Conserved Domains (3) summary
      TIGR00927
      Location:260513
      2A1904; K+-dependent Na+/Ca+ exchanger
      TIGR02168
      Location:7601430
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
      pfam05104
      Location:33168
      Rib_recp_KP_reg; Ribosome receptor lysine/proline rich region
    3. XM_006500443.1XP_006500506.1  ribosome-binding protein 1 isoform X4

      Conserved Domains (1) summary
      TIGR02168
      Location:111813
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    4. XM_006500444.5XP_006500507.1  ribosome-binding protein 1 isoform X5

      Conserved Domains (1) summary
      TIGR02168
      Location:63765
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
    5. XM_036162731.1XP_036018624.1  ribosome-binding protein 1 isoform X3

      Conserved Domains (1) summary
      TIGR02168
      Location:203847
      SMC_prok_B; chromosome segregation protein SMC, common bacterial type
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