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    PS2 Presenilin-2 [ Arabidopsis thaliana (thale cress) ]

    Gene ID: 817540, updated on 15-Oct-2023

    Summary

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    Gene symbol
    PS2
    Gene description
    Presenilin-2
    Primary source
    Araport:AT2G29900
    Locus tag
    AT2G29900
    Gene type
    protein coding
    RefSeq status
    REVIEWED
    Organism
    Arabidopsis thaliana (ecotype: Columbia)
    Lineage
    Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta; Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae; rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis
    Also known as
    F6K5.3; F6K5_3; Presenilin-2
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    Genomic context

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    Location:
    chromosome: 2
    Exon count:
    1
    Sequence:
    Chromosome: 2; NC_003071.7 (12749743..12751146)

    Chromosome 2 - NC_003071.7Genomic Context describing neighboring genes Neighboring gene Myb/SANT-like DNA-binding domain protein Neighboring gene villin-like 1 Neighboring gene F-box/RNI-like superfamily protein Neighboring gene uncharacterized protein Neighboring gene uncharacterized protein

    Genomic regions, transcripts, and products

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    Genomic Sequence:
    NC_003071.7

    Go to nucleotide: Graphics FASTA GenBank

    Bibliography

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    Related articles in PubMed

    1. Gamma-secretase subunits associate in intracellular membrane compartments in Arabidopsis thaliana. Smolarkiewicz M, et al. J Exp Bot, 2014 Jul. PMID 24723404, Free PMC Article
    2. Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana. Lin X, et al. Nature, 1999 Dec 16. PMID 10617197

    GeneRIFs: Gene References Into Functions

    Interactions

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    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

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    Homology

    NM_128544.4

    Gene Ontology Provided by TAIR

    Function Evidence Code Pubs
    enables aspartic endopeptidase activity, intramembrane cleaving IEA
    Inferred from Electronic Annotation
    more info
    		  
    Process Evidence Code Pubs
    involved_in protein processing IEA
    Inferred from Electronic Annotation
    more info
    		  
    Component Evidence Code Pubs
    located_in Golgi-associated vesicle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 
    located_in intracellular membrane-bounded organelle IDA
    Inferred from Direct Assay
    more info
    		 PubMed 

    General protein information

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    Preferred Names
    Presenilin-2
    NP_180551.1
    • Presenilin-2 (PS2); FUNCTIONS IN: molecular_function unknown; INVOLVED IN: intracellular signaling pathway; LOCATED IN: integral to membrane, membrane; EXPRESSED IN: 24 plant structures; EXPRESSED DURING: 13 growth stages; CONTAINS InterPro DOMAIN/s: Peptidase A22, presenilin signal peptide (InterPro:IPR006639), Peptidase A22A, presenilin (InterPro:IPR001108); BEST Arabidopsis thaliana protein match is: Presenilin-1 (TAIR:AT1G08700.1); Has 475 Blast hits to 452 proteins in 108 species: Archae - 2; Bacteria - 0; Metazoa - 334; Fungi - 0; Plants - 63; Viruses - 0; Other Eukaryotes - 76 (source: NCBI BLink).

    NCBI Reference Sequences (RefSeq)

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    Genome Annotation

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference assembly

    Genomic

    1. NC_003071.7 Reference assembly

      Range
      12749743..12751146
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. NM_128544.4 → NP_180551.1  Presenilin-2 [Arabidopsis thaliana]

      See identical proteins and their annotated locations for NP_180551.1

      Status: REVIEWED

      UniProtKB/Swiss-Prot
      Q0IGK6, Q9SIK7
      UniProtKB/TrEMBL
      A0A178VTM4, Q0WT05
      Conserved Domains (1) summary
      pfam01080
      Location:15 → 387
      Presenilin
    Nucleotide Protein
    Heading Accession and Version
    Protein Accession Links
    GenPept Link UniProtKB Link
    Q9SIK7.1

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