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    Sil1 endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae) [ Mus musculus (house mouse) ]

    Gene ID: 81500, updated on 23-Jun-2021

    Summary

    Official Symbol
    Sil1provided by MGI
    Official Full Name
    endoplasmic reticulum chaperone SIL1 homolog (S. cerevisiae)provided by MGI
    Primary source
    MGI:MGI:1932040
    See related
    Ensembl:ENSMUSG00000024357
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    wz; AI042831; 1810057E01Rik
    Expression
    Ubiquitous expression in testis adult (RPKM 27.6), adrenal adult (RPKM 12.9) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Sil1 in Genome Data Viewer
    Location:
    18; 18 B1- B2
    Exon count:
    15
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 18 NC_000084.7 (35399449..35632443, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 18 NC_000084.6 (35266396..35499390, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 18 NC_000084.5 (35426050..35658579, complement)

    Chromosome 18 - NC_000084.7Genomic Context describing neighboring genes Neighboring gene predicted gene, 46617 Neighboring gene catenin (cadherin associated protein), alpha 1 Neighboring gene leucine rich repeat transmembrane neuronal 2 Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC118568353 Neighboring gene predicted gene, 41691 Neighboring gene ubiquitin A-52 residue ribosomal protein fusion product 1 pseudogene

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables adenyl-nucleotide exchange factor activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables identical protein binding ISO
    Inferred from Sequence Orthology
    more info
     
    Process Evidence Code Pubs
    acts_upstream_of_or_within protein transport IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    located_in endoplasmic reticulum IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in endoplasmic reticulum ISO
    Inferred from Sequence Orthology
    more info
     

    General protein information

    Preferred Names
    nucleotide exchange factor SIL1

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001360814.1NP_001347743.1  nucleotide exchange factor SIL1 precursor

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longer transcript. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      AC121874, AC147989, AC153145
      Consensus CDS
      CCDS29140.1
      Conserved Domains (1) summary
      pfam08609
      Location:196226
      Fes1; Nucleotide exchange factor Fes1
    2. NM_030749.2NP_109674.2  nucleotide exchange factor SIL1 precursor

      See identical proteins and their annotated locations for NP_109674.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) differs in the 5' UTR compared to variant 1. Both variants 1 and 2 encode the same protein.
      Source sequence(s)
      BP771607, BX512650, CO428760, CX219879
      Consensus CDS
      CCDS29140.1
      UniProtKB/Swiss-Prot
      Q9EPK6
      Related
      ENSMUSP00000025215.9, ENSMUST00000025215.10
      Conserved Domains (1) summary
      pfam08609
      Location:196226
      Fes1; Nucleotide exchange factor Fes1

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000084.7 Reference GRCm39 C57BL/6J

      Range
      35399449..35632443 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_030250634.1XP_030106494.1  nucleotide exchange factor SIL1 isoform X1

    2. XM_036161310.1XP_036017203.1  nucleotide exchange factor SIL1 isoform X1

    3. XM_011247043.3XP_011245345.1  nucleotide exchange factor SIL1 isoform X1

      See identical proteins and their annotated locations for XP_011245345.1

      UniProtKB/Swiss-Prot
      Q9EPK6
      Conserved Domains (1) summary
      pfam08609
      Location:196226
      Fes1; Nucleotide exchange factor Fes1
    4. XM_006526365.4XP_006526428.1  nucleotide exchange factor SIL1 isoform X1

      See identical proteins and their annotated locations for XP_006526428.1

      UniProtKB/Swiss-Prot
      Q9EPK6
      Conserved Domains (1) summary
      pfam08609
      Location:196226
      Fes1; Nucleotide exchange factor Fes1
    5. XM_030250635.1XP_030106495.1  nucleotide exchange factor SIL1 isoform X2

    6. XM_006526367.5XP_006526430.1  nucleotide exchange factor SIL1 isoform X3

      Conserved Domains (1) summary
      pfam08609
      Location:197226
      Fes1; Nucleotide exchange factor Fes1
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