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    N4bp1 NEDD4 binding protein 1 [ Mus musculus (house mouse) ]

    Gene ID: 80750, updated on 23-Jun-2021

    Summary

    Official Symbol
    N4bp1provided by MGI
    Official Full Name
    NEDD4 binding protein 1provided by MGI
    Primary source
    MGI:MGI:2136825
    See related
    Ensembl:ENSMUSG00000031652
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    C81621; AI481586
    Expression
    Ubiquitous expression in stomach adult (RPKM 8.2), duodenum adult (RPKM 8.2) and 28 other tissues See more
    Orthologs
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    Genomic context

    See N4bp1 in Genome Data Viewer
    Location:
    8; 8 C3
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 8 NC_000074.7 (87567764..87612489, complement)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 8 NC_000074.6 (86841136..86885296, complement)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 8 NC_000074.5 (89365038..89409157, complement)

    Chromosome 8 - NC_000074.7Genomic Context describing neighboring genes Neighboring gene siah E3 ubiquitin protein ligase 1A Neighboring gene predicted gene 10638 Neighboring gene predicted gene, 39215 Neighboring gene predicted gene, 33877 Neighboring gene ferritin heavy chain, pseudogene 3 Neighboring gene predicted gene, 33391

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Clone Names

    • MGC7607

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables RNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables hydrolase activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables mRNA binding ISO
    Inferred from Sequence Orthology
    more info
     
    enables nuclease activity IEA
    Inferred from Electronic Annotation
    more info
     
    enables protein binding IPI
    Inferred from Physical Interaction
    more info
    PubMed 
    enables ribonuclease activity ISO
    Inferred from Sequence Orthology
    more info
     
    enables ubiquitin binding ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    is_active_in PML body IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in PML body IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in cytoplasm IEA
    Inferred from Electronic Annotation
    more info
     
    located_in cytosol IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in nucleolus IDA
    Inferred from Direct Assay
    more info
    PubMed 
    is_active_in nucleus IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleus IDA
    Inferred from Direct Assay
    more info
    PubMed 

    NCBI Reference Sequences (RefSeq)

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    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030563.2NP_085040.2  NEDD4-binding protein 1

      See identical proteins and their annotated locations for NP_085040.2

      Status: VALIDATED

      Source sequence(s)
      AA444325, AK147522, BC089324, BM951093, CJ134294, CX122841, CX240926
      Consensus CDS
      CCDS52625.1
      UniProtKB/Swiss-Prot
      Q6A037
      UniProtKB/TrEMBL
      Q5EBQ4
      Related
      ENSMUSP00000034074.8, ENSMUST00000034074.8
      Conserved Domains (1) summary
      pfam11977
      Location:614767
      RNase_Zc3h12a; Zc3h12a-like Ribonuclease NYN domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000074.7 Reference GRCm39 C57BL/6J

      Range
      87567764..87612489 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_006531517.4XP_006531580.1  NEDD4-binding protein 1 isoform X3

    2. XM_006531516.4XP_006531579.1  NEDD4-binding protein 1 isoform X1

      Conserved Domains (1) summary
      cl20439
      Location:628691
      RNase_Zc3h12a; Zc3h12a-like Ribonuclease NYN domain
    3. XM_036154392.1XP_036010285.1  NEDD4-binding protein 1 isoform X2

      Conserved Domains (2) summary
      cd18728
      Location:532658
      PIN_N4BP1-like; PRORP-like PIN domain of NEDD4 binding protein 1 and related proteins
      cl00098
      Location:156
      KH-I; K homology (KH) RNA-binding domain, type I
    4. XM_036154391.1XP_036010284.1  NEDD4-binding protein 1 isoform X2

      Conserved Domains (2) summary
      cd18728
      Location:532658
      PIN_N4BP1-like; PRORP-like PIN domain of NEDD4 binding protein 1 and related proteins
      cl00098
      Location:156
      KH-I; K homology (KH) RNA-binding domain, type I
    5. XM_036154393.1XP_036010286.1  NEDD4-binding protein 1 isoform X4

      Conserved Domains (1) summary
      cl00098
      Location:156
      KH-I; K homology (KH) RNA-binding domain, type I

    RNA

    1. XR_004934903.1 RNA Sequence

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