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    Mynn myoneurin [ Mus musculus (house mouse) ]

    Gene ID: 80732, updated on 23-Jun-2021

    Summary

    Official Symbol
    Mynnprovided by MGI
    Official Full Name
    myoneurinprovided by MGI
    Primary source
    MGI:MGI:1931415
    See related
    Ensembl:ENSMUSG00000037730
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    Mynr; SBBI; SBBIZ1; AA415053; AI661031; AW049392; 2810011C24Rik
    Expression
    Ubiquitous expression in limb E14.5 (RPKM 3.7), CNS E11.5 (RPKM 3.7) and 28 other tissues See more
    Orthologs
    NEW
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    Try the new Transcript table

    Genomic context

    See Mynn in Genome Data Viewer
    Location:
    3; 3 A3
    Exon count:
    8
    Annotation release Status Assembly Chr Location
    109 current GRCm39 (GCF_000001635.27) 3 NC_000069.7 (30656212..30674022)
    108.20200622 previous assembly GRCm38.p6 (GCF_000001635.26) 3 NC_000069.6 (30602087..30619873)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 3 NC_000069.5 (30501009..30517419)

    Chromosome 3 - NC_000069.7Genomic Context describing neighboring genes Neighboring gene actin related protein T3 Neighboring gene nuclear encoded tRNA valine 8 (anticodon AAC) Neighboring gene leucine rich repeat containing 34 Neighboring gene leucine-rich repeats and IQ motif containing 4 Neighboring gene leucine rich repeat containing 31 Neighboring gene predicted gene 15462

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)
    • Endonuclease-mediated (1) 

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Homology

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    enables DNA binding IEA
    Inferred from Electronic Annotation
    more info
     
    enables DNA-binding transcription repressor activity, RNA polymerase II-specific IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    enables metal ion binding IEA
    Inferred from Electronic Annotation
    more info
     
    Component Evidence Code Pubs
    is_active_in nucleoplasm IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    located_in nucleoplasm ISO
    Inferred from Sequence Orthology
    more info
     
    located_in nucleus IEA
    Inferred from Electronic Annotation
    more info
     

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001289621.1NP_001276550.1  myoneurin isoform 2

      See identical proteins and their annotated locations for NP_001276550.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (2) lacks an alternate in-frame exon compared to variant 1. The resulting isoform (2) has the same N- and C-termini but is shorter compared to isoform 1.
      Source sequence(s)
      AC120377, AK014315, BC065084, BF465039
      Consensus CDS
      CCDS79891.1
      UniProtKB/Swiss-Prot
      Q99MD8
      Related
      ENSMUSP00000041034.9, ENSMUST00000047502.9
      Conserved Domains (5) summary
      smart00225
      Location:25118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:304324
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:304324
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:14115
      BTB; BTB/POZ domain
      pfam13465
      Location:316341
      zf-H2C2_2; Zinc-finger double domain
    2. NM_001289622.1NP_001276551.1  myoneurin isoform 3

      See identical proteins and their annotated locations for NP_001276551.1

      Status: VALIDATED

      Description
      Transcript Variant: This variant (3) uses an alternate splice junction at the 3' end of an exon compared to variant 1. The resulting isoform (3) is shorter at the N-terminus compared to isoform 1.
      Source sequence(s)
      AC120377, AK163261, BC065084, BF465039
      UniProtKB/Swiss-Prot
      Q99MD8
      Conserved Domains (4) summary
      COG5189
      Location:240324
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:190210
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:190210
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:202227
      zf-H2C2_2; Zinc-finger double domain
    3. NM_001289623.1NP_001276552.1  myoneurin isoform 4

      Status: VALIDATED

      Description
      Transcript Variant: This variant (4) uses an alternate splice junction at the 3' end of an exon and lacks an alternate in-frame exon compared to variant 1. The resulting isoform (4) is shorter at the N-terminus and lacks an alternate internal segment compared to isoform 1.
      Source sequence(s)
      AC120377, AK030898, BC065084, BF465039
      UniProtKB/Swiss-Prot
      Q99MD8
      Conserved Domains (3) summary
      sd00017
      Location:190210
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:190210
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:202227
      zf-H2C2_2; Zinc-finger double domain
    4. NM_030557.3NP_085034.2  myoneurin isoform 1

      See identical proteins and their annotated locations for NP_085034.2

      Status: VALIDATED

      Description
      Transcript Variant: This variant (1) represents the longest transcript and encodes the longest isoform (1).
      Source sequence(s)
      AC120377, BC065084, BF465039
      Consensus CDS
      CCDS17284.1
      UniProtKB/Swiss-Prot
      Q99MD8
      Related
      ENSMUSP00000141951.2, ENSMUST00000192715.6
      Conserved Domains (5) summary
      smart00225
      Location:25118
      BTB; Broad-Complex, Tramtrack and Bric a brac
      sd00017
      Location:304324
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:304324
      zf-C2H2; Zinc finger, C2H2 type
      pfam00651
      Location:14115
      BTB; BTB/POZ domain
      pfam13465
      Location:316341
      zf-H2C2_2; Zinc-finger double domain

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 109 details...Open this link in a new tab

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm39 C57BL/6J

    Genomic

    1. NC_000069.7 Reference GRCm39 C57BL/6J

      Range
      30656212..30674022
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_036163419.1XP_036019312.1  myoneurin isoform X1

      Conserved Domains (4) summary
      COG5189
      Location:240324
      SFP1; Putative transcriptional repressor regulating G2/M transition [Transcription / Cell division and chromosome partitioning]
      sd00017
      Location:190210
      ZF_C2H2; C2H2 Zn finger [structural motif]
      pfam00096
      Location:190210
      zf-C2H2; Zinc finger, C2H2 type
      pfam13465
      Location:202227
      zf-H2C2_2; Zinc-finger double domain
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