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    Pofut2 protein O-fucosyltransferase 2 [ Mus musculus (house mouse) ]

    Gene ID: 80294, updated on 23-May-2018

    Summary

    Official Symbol
    Pofut2provided by MGI
    Official Full Name
    protein O-fucosyltransferase 2provided by MGI
    Primary source
    MGI:MGI:1916863
    See related
    Ensembl:ENSMUSG00000020260
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Mus musculus
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Muridae; Murinae; Mus; Mus
    Also known as
    FUT13; AI256847; BC003494; C21orf80; 2310011G23Rik
    Expression
    Ubiquitous expression in ovary adult (RPKM 51.4), limb E14.5 (RPKM 44.3) and 28 other tissues See more
    Orthologs

    Genomic context

    See Pofut2 in Genome Data Viewer
    Location:
    10; 10 C1
    Exon count:
    9
    Annotation release Status Assembly Chr Location
    106 current GRCm38.p4 (GCF_000001635.24) 10 NC_000076.6 (77259223..77269586)
    Build 37.2 previous assembly MGSCv37 (GCF_000001635.18) 10 NC_000076.5 (76722045..76732331)

    Chromosome 10 - NC_000076.6Genomic Context describing neighboring genes Neighboring gene predicted gene, 40703 Neighboring gene predicted gene 10941 Neighboring gene adenosine deaminase, RNA-specific, B1 Neighboring gene predicted gene, 17769

    Genomic regions, transcripts, and products

    Expression

    • Project title: Mouse ENCODE transcriptome data
    • Description: RNA profiling data sets generated by the Mouse ENCODE project.
    • BioProject: PRJNA66167
    • Publication: PMID 25409824
    • Analysis date: n/a

    Variation

    Alleles

    Alleles of this type are documented at Mouse Genome Informatics  (MGI)

    Pathways from BioSystems

    General gene information

    Markers

    Homology

    Clone Names

    • MGC6943, MGC25565

    Gene Ontology Provided by MGI

    Function Evidence Code Pubs
    fucosyltransferase activity IDA
    Inferred from Direct Assay
    more info
    PubMed 
    peptide-O-fucosyltransferase activity IBA
    Inferred from Biological aspect of Ancestor
    more info
    PubMed 
    peptide-O-fucosyltransferase activity ISO
    Inferred from Sequence Orthology
    more info
     
    transferase activity IEA
    Inferred from Electronic Annotation
    more info
     
    transferase activity, transferring glycosyl groups IEA
    Inferred from Electronic Annotation
    more info
     
    Process Evidence Code Pubs
    carbohydrate metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    fucose metabolic process IEA
    Inferred from Electronic Annotation
    more info
     
    fucosylation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    mesoderm formation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    protein O-linked fucosylation ISO
    Inferred from Sequence Orthology
    more info
     
    regulation of epithelial to mesenchymal transition IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of gene expression IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    regulation of secretion ISO
    Inferred from Sequence Orthology
    more info
     
    Component Evidence Code Pubs
    Golgi apparatus ISO
    Inferred from Sequence Orthology
    more info
     
    endoplasmic reticulum IEA
    Inferred from Electronic Annotation
    more info
     

    General protein information

    Preferred Names
    GDP-fucose protein O-fucosyltransferase 2
    Names
    O-FucT-2
    peptide-O-fucosyltransferase 2
    NP_084538.2

    NCBI Reference Sequences (RefSeq)

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_030262.3NP_084538.2  GDP-fucose protein O-fucosyltransferase 2 precursor

      See identical proteins and their annotated locations for NP_084538.2

      Status: VALIDATED

      Source sequence(s)
      AF455270, AK148244, CO814561
      Consensus CDS
      CCDS23954.1
      UniProtKB/Swiss-Prot
      Q8VHI3
      UniProtKB/TrEMBL
      B2RV73
      Related
      ENSMUSP00000020493.7, ENSMUST00000020493.8
      Conserved Domains (1) summary
      cd11298
      Location:45414
      O-FucT-2; GDP-fucose protein O-fucosyltransferase 2

    RefSeqs of Annotated Genomes: Mus musculus Annotation Release 106

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCm38.p4 C57BL/6J

    Genomic

    1. NC_000076.6 Reference GRCm38.p4 C57BL/6J

      Range
      77259223..77269586
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    RNA

    1. XR_001779639.1 RNA Sequence

    2. XR_380457.3 RNA Sequence

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