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    C10orf88 chromosome 10 open reading frame 88 [ Homo sapiens (human) ]

    Gene ID: 80007, updated on 5-Mar-2024

    Summary

    Official Symbol
    C10orf88provided by HGNC
    Official Full Name
    chromosome 10 open reading frame 88provided by HGNC
    Primary source
    HGNC:HGNC:25822
    See related
    Ensembl:ENSG00000119965 MIM:620661; AllianceGenome:HGNC:25822
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    PAAT
    Summary
    Predicted to enable identical protein binding activity. Located in mitochondrion. [provided by Alliance of Genome Resources, Apr 2022]
    Expression
    Broad expression in testis (RPKM 4.0), brain (RPKM 1.9) and 24 other tissues See more
    Orthologs
    NEW
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    Genomic context

    See C10orf88 in Genome Data Viewer
    Location:
    10q26.13
    Exon count:
    6
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 10 NC_000010.11 (122930901..122954227, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 10 NC_060934.1 (123805885..123829210, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 10 NC_000010.10 (124690417..124713743, complement)

    Chromosome 10 - NC_000010.11Genomic Context describing neighboring genes Neighboring gene FAM24B-CUZD1 readthrough Neighboring gene family with sequence similarity 24 member B Neighboring gene ReSE screen-validated silencer GRCh37_chr10:124644309-124644439 Neighboring gene C10orf88B (pseudogene) Neighboring gene Sharpr-MPRA regulatory region 13232 Neighboring gene family with sequence similarity 24 member A Neighboring gene ATAC-STARR-seq lymphoblastoid silent region 2894 Neighboring gene uncharacterized LOC124902519 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 4143 Neighboring gene phosphoseryl-tRNA kinase

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    ATPase PAAT
    Names
    protein associated with ABC transporters
    uncharacterized protein C10orf88
    NP_079218.2

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_024942.4NP_079218.2  ATPase PAAT

      See identical proteins and their annotated locations for NP_079218.2

      Status: VALIDATED

      Source sequence(s)
      AC073585, BC032645, CB044034
      Consensus CDS
      CCDS7632.1
      UniProtKB/Swiss-Prot
      Q0P6C6, Q8N597, Q9H8K7
      Related
      ENSP00000419126.1, ENST00000481909.2
      Conserved Domains (1) summary
      pfam14958
      Location:59197
      DUF4506; Domain of unknown function (DUF4506)

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000010.11 Reference GRCh38.p14 Primary Assembly

      Range
      122930901..122954227 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060934.1 Alternate T2T-CHM13v2.0

      Range
      123805885..123829210 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)