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    MAP9 microtubule associated protein 9 [ Homo sapiens (human) ]

    Gene ID: 79884, updated on 3-Apr-2024

    Summary

    Official Symbol
    MAP9provided by HGNC
    Official Full Name
    microtubule associated protein 9provided by HGNC
    Primary source
    HGNC:HGNC:26118
    See related
    Ensembl:ENSG00000164114 MIM:610070; AllianceGenome:HGNC:26118
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    ASAP
    Summary
    ASAP is a microtubule-associated protein required for spindle function, mitotic progression, and cytokinesis (Saffin et al., 2005 [PubMed 16049101]).[supplied by OMIM, Mar 2008]
    Expression
    Broad expression in brain (RPKM 7.7), thyroid (RPKM 7.3) and 23 other tissues See more
    Orthologs
    NEW
    Try the new Gene table
    Try the new Transcript table

    Genomic context

    See MAP9 in Genome Data Viewer
    Location:
    4q32.1
    Exon count:
    14
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 4 NC_000004.12 (155342658..155376965, complement)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 4 NC_060928.1 (158674560..158709763, complement)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 4 NC_000004.11 (156263810..156298117, complement)

    Chromosome 4 - NC_000004.12Genomic Context describing neighboring genes Neighboring gene neuropeptide Y receptor Y2 Neighboring gene NPY2R antisense RNA 1 Neighboring gene uncharacterized LOC105377502 Neighboring gene MAP9 antisense RNA 1 Neighboring gene ATAC-STARR-seq lymphoblastoid active region 22081 Neighboring gene TBC1 domain family member 3C pseudogene Neighboring gene tyrosine 3-monooxygenase/tryptophan 5-monooxygenase activation protein epsilon pseudogene 4

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Bibliography

    GeneRIFs: Gene References Into Functions

    What's a GeneRIF?

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General gene information

    Markers

    Clone Names

    • FLJ21159

    Gene Ontology Provided by GOA

    Function Evidence Code Pubs
    enables microtubule binding IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    enables microtubule binding IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Process Evidence Code Pubs
    involved_in mitotic cytokinesis IEA
    Inferred from Electronic Annotation
    more info
     
    involved_in mitotic spindle assembly IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in mitotic spindle assembly IDA
    Inferred from Direct Assay
    more info
    PubMed 
    involved_in regulation of mitotic centrosome separation IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of mitotic cytokinesis IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    involved_in regulation of mitotic cytokinesis IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    involved_in regulation of mitotic spindle organization IMP
    Inferred from Mutant Phenotype
    more info
    PubMed 
    Component Evidence Code Pubs
    is_active_in astral microtubule IBA
    Inferred from Biological aspect of Ancestor
    more info
     
    located_in astral microtubule IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in axon ISS
    Inferred from Sequence or Structural Similarity
    more info
     
    located_in cytoplasm IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitotic spindle IDA
    Inferred from Direct Assay
    more info
    PubMed 
    located_in mitotic spindle midzone IEA
    Inferred from Electronic Annotation
    more info
     
    located_in spindle midzone IDA
    Inferred from Direct Assay
    more info
    PubMed 

    General protein information

    Preferred Names
    microtubule-associated protein 9
    Names
    aster-associated protein

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001039580.2NP_001034669.1  microtubule-associated protein 9

      See identical proteins and their annotated locations for NP_001034669.1

      Status: VALIDATED

      Source sequence(s)
      AC097467, AY690636, BC022852, CF144347
      Consensus CDS
      CCDS35493.1
      UniProtKB/Swiss-Prot
      Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
      UniProtKB/TrEMBL
      B9EJB6
      Related
      ENSP00000310593.4, ENST00000311277.9
      Conserved Domains (1) summary
      cl01868
      Location:521597
      YukC; WXG100 protein secretion system (Wss), protein YukC

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000004.12 Reference GRCh38.p14 Primary Assembly

      Range
      155342658..155376965 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011532255.4XP_011530557.1  microtubule-associated protein 9 isoform X3

      UniProtKB/TrEMBL
      B9EJB6
      Conserved Domains (1) summary
      cl01868
      Location:449525
      YukC; WXG100 protein secretion system (Wss), protein YukC
    2. XM_011532254.2XP_011530556.1  microtubule-associated protein 9 isoform X1

      See identical proteins and their annotated locations for XP_011530556.1

      UniProtKB/Swiss-Prot
      Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
      UniProtKB/TrEMBL
      B9EJB6
      Conserved Domains (1) summary
      cl01868
      Location:521597
      YukC; WXG100 protein secretion system (Wss), protein YukC
    3. XM_017008616.2XP_016864105.1  microtubule-associated protein 9 isoform X2

      UniProtKB/TrEMBL
      B9EJB6
      Conserved Domains (2) summary
      PTZ00121
      Location:280620
      PTZ00121; MAEBL; Provisional
      PRK12704
      Location:506591
      PRK12704; phosphodiesterase; Provisional
    4. XM_011532253.2XP_011530555.1  microtubule-associated protein 9 isoform X1

      See identical proteins and their annotated locations for XP_011530555.1

      UniProtKB/Swiss-Prot
      Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
      UniProtKB/TrEMBL
      B9EJB6
      Conserved Domains (1) summary
      cl01868
      Location:521597
      YukC; WXG100 protein secretion system (Wss), protein YukC
    5. XM_017008617.2XP_016864106.1  microtubule-associated protein 9 isoform X2

      UniProtKB/TrEMBL
      B9EJB6
      Conserved Domains (2) summary
      PTZ00121
      Location:280620
      PTZ00121; MAEBL; Provisional
      PRK12704
      Location:506591
      PRK12704; phosphodiesterase; Provisional

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060928.1 Alternate T2T-CHM13v2.0

      Range
      158674560..158709763 complement
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054350850.1XP_054206825.1  microtubule-associated protein 9 isoform X3

    2. XM_054350847.1XP_054206822.1  microtubule-associated protein 9 isoform X1

      UniProtKB/Swiss-Prot
      Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    3. XM_054350848.1XP_054206823.1  microtubule-associated protein 9 isoform X2

    4. XM_054350846.1XP_054206821.1  microtubule-associated protein 9 isoform X1

      UniProtKB/Swiss-Prot
      Q49MG5, Q4W5I7, Q68DU1, Q9H781, Q9H7B6
    5. XM_054350849.1XP_054206824.1  microtubule-associated protein 9 isoform X2

    Suppressed Reference Sequence(s)

    The following Reference Sequences have been suppressed. Explain

    1. NM_024826.1: Suppressed sequence

      Description
      NM_024826.1: This RefSeq record was removed by NCBI staff. Contact info@ncbi.nlm.nih.gov for further information.