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    OR4K1 olfactory receptor family 4 subfamily K member 1 [ Homo sapiens (human) ]

    Gene ID: 79544, updated on 17-Jun-2024

    Summary

    Official Symbol
    OR4K1provided by HGNC
    Official Full Name
    olfactory receptor family 4 subfamily K member 1provided by HGNC
    Primary source
    HGNC:HGNC:14726
    See related
    Ensembl:ENSG00000155249 AllianceGenome:HGNC:14726
    Gene type
    protein coding
    RefSeq status
    VALIDATED
    Organism
    Homo sapiens
    Lineage
    Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
    Also known as
    OR14-19
    Summary
    Olfactory receptors interact with odorant molecules in the nose, to initiate a neuronal response that triggers the perception of a smell. The olfactory receptor proteins are members of a large family of G-protein-coupled receptors (GPCR) arising from single coding-exon genes. Olfactory receptors share a 7-transmembrane domain structure with many neurotransmitter and hormone receptors and are responsible for the recognition and G protein-mediated transduction of odorant signals. The olfactory receptor gene family is the largest in the genome. The nomenclature assigned to the olfactory receptor genes and proteins for this organism is independent of other organisms. [provided by RefSeq, Jul 2008]
    Expression
    Low expression observed in reference dataset See more
    Orthologs
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    Genomic context

    See OR4K1 in Genome Data Viewer
    Location:
    14q11.2
    Exon count:
    3
    Annotation release Status Assembly Chr Location
    RS_2023_10 current GRCh38.p14 (GCF_000001405.40) 14 NC_000014.9 (19920263..19936757)
    RS_2023_10 current T2T-CHM13v2.0 (GCF_009914755.1) 14 NC_060938.1 (14119705..14136196)
    105.20220307 previous assembly GRCh37.p13 (GCF_000001405.25) 14 NC_000014.8 (20399076..20404916)

    Chromosome 14 - NC_000014.9Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC124903278 Neighboring gene ATPase Na+/K+ transporting subunit beta 3 pseudogene Neighboring gene olfactory receptor family 4 subfamily K member 4 pseudogene Neighboring gene olfactory receptor family 4 subfamily K member 5 Neighboring gene olfactory receptor family 4 subfamily K member 16 pseudogene Neighboring gene olfactory receptor family 4 subfamily K member 15

    Genomic regions, transcripts, and products

    Expression

    • Project title: HPA RNA-seq normal tissues
    • Description: RNA-seq was performed of tissue samples from 95 human individuals representing 27 different tissues in order to determine tissue-specificity of all protein-coding genes
    • BioProject: PRJEB4337
    • Publication: PMID 24309898
    • Analysis date: Wed Apr 4 07:08:55 2018

    Interactions

    Products Interactant Other Gene Complex Source Pubs Description

    General protein information

    Preferred Names
    olfactory receptor 4K1
    Names
    olfactory receptor OR14-19

    NCBI Reference Sequences (RefSeq)

    NEW Try the new Transcript table

    RefSeqs maintained independently of Annotated Genomes

    These reference sequences exist independently of genome builds. Explain

    These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

    mRNA and Protein(s)

    1. NM_001004063.3NP_001004063.2  olfactory receptor 4K1

      See identical proteins and their annotated locations for NP_001004063.2

      Status: VALIDATED

      Source sequence(s)
      AL359218, AL391156
      Consensus CDS
      CCDS32025.1
      UniProtKB/Swiss-Prot
      B9EKV9, Q8NGD4, Q8NGD6, Q96R73
      UniProtKB/TrEMBL
      A0A126GVR2
      Related
      ENSP00000493193.1, ENST00000641172.1
      Conserved Domains (2) summary
      pfam00001
      Location:41287
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31301
      7tm_4; Olfactory receptor

    RefSeqs of Annotated Genomes: GCF_000001405.40-RS_2023_10

    The following sections contain reference sequences that belong to a specific genome build. Explain

    Reference GRCh38.p14 Primary Assembly

    Genomic

    1. NC_000014.9 Reference GRCh38.p14 Primary Assembly

      Range
      19920263..19936757
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_011537153.3XP_011535455.1  olfactory receptor 4K1 isoform X1

      See identical proteins and their annotated locations for XP_011535455.1

      UniProtKB/Swiss-Prot
      B9EKV9, Q8NGD4, Q8NGD6, Q96R73
      UniProtKB/TrEMBL
      A0A126GVR2
      Related
      ENSP00000493205.1, ENST00000641429.1
      Conserved Domains (2) summary
      pfam00001
      Location:41287
      7tm_1; 7 transmembrane receptor (rhodopsin family)
      cl21561
      Location:31301
      7tm_4; Olfactory receptor

    Reference GRCh38.p14 PATCHES

    Genomic

    1. NW_025791796.1 Reference GRCh38.p14 PATCHES

      Range
      122945..139439
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054333150.1XP_054189125.1  olfactory receptor 4K1 isoform X1

      UniProtKB/Swiss-Prot
      B9EKV9, Q8NGD4, Q8NGD6, Q96R73
      UniProtKB/TrEMBL
      A0A126GVR2

    Alternate T2T-CHM13v2.0

    Genomic

    1. NC_060938.1 Alternate T2T-CHM13v2.0

      Range
      14119705..14136196
      Download
      GenBank, FASTA, Sequence Viewer (Graphics)

    mRNA and Protein(s)

    1. XM_054376711.1XP_054232686.1  olfactory receptor 4K1 isoform X1

      UniProtKB/TrEMBL
      A0A126GVR2